Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Wen-Jin Chen"'
Autor:
Si-chen Di, Wen-jin Chen, Wei Yang, Xiang-min Zhang, Ke-qin Dong, Yi-jun Tian, Ye Sun, Cheng Qian, Jia-xin Chen, Zi-chang Liu, Zi-xuan Gong, Jian Chu, Wang Zhou, Xiu-wu Pan, Xin-gang Cui
Publikováno v:
Cell Death and Disease, Vol 15, Iss 7, Pp 1-13 (2024)
Abstract Renal cell carcinoma (RCC) is considered a “metabolic disease” characterized by elevated glycolysis in patients with advanced RCC. Tyrosine kinase inhibitor (TKI) therapy is currently an important treatment option for advanced RCC, but d
Externí odkaz:
https://doaj.org/article/78619da7dff9410ab9cd5808a6be5d1a
Autor:
Xin Zhao, Wen-Kai Zheng, Xiu-Huan Wang, Jiao Fang, Wen-Jin Chen, Na Li, Hai-Tao Wen, Xiu-Juan Feng, Mei-Fang Wang, Chun-Ni Heng, Wei-Na Cao
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
BackgroundA positive professional identity is key for nursing students in determining career direction and predicting future engagement in the profession. Despite its complexity and susceptibility to various influences, the factors shaping nursing st
Externí odkaz:
https://doaj.org/article/97f419d810454202b63ae00021a5237c
Autor:
Da Xu, LI Zuo, Wang Zhou, Yu-Qi Wang, Wen-Jin Chen, Ke-Qin Dong, Jia-Xin Chen, Wei-Jie Chen, Wen-Yan Li, Zi-Chang Liu, Zheng-Yu Jiang, Yi-Fan Tang, Yu-Xuan Qin, Lin-Hui Wang, Xiu-Wu Pan, Xin-Gang Cui
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 6 (2024)
Background Tertiary lymphoid structures (TLSs) serve as organized lymphoid aggregates that influence immune responses within the tumor microenvironment. This study aims to investigate the characteristics and clinical significance of TLSs and tumor-in
Externí odkaz:
https://doaj.org/article/a822db8f99ba4850b4ab5171fa2903aa
Publikováno v:
Chinese Medicine, Vol 18, Iss 1, Pp 1-15 (2023)
Abstract Background Knee osteoarthritis (KOA) has a complex pathological mechanism and is difficult to cure. The traditional medicine Du Huo Ji Sheng Tang (DHJST) has been used for the treatment of KOA for more than one thousand years, but its mechan
Externí odkaz:
https://doaj.org/article/c675f6f611684f6596e3a520d74fad99
Autor:
Xiu-wu Pan, Wen-jin Chen, Da Xu, Wen-bin Guan, Lin Li, Jia-xin Chen, Wei-jie Chen, Ke-qin Dong, Jian-qing Ye, Si-shun Gan, Wang Zhou, Xin-gang Cui
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108370- (2023)
Summary: Previous bulk RNA sequencing or whole genome sequencing on clear cell renal cell carcinoma (ccRCC) subtyping mainly focused on ccRCC cell origin or the complex tumor microenvironment (TME). Based on the single-cell RNA sequencing (scRNA-seq)
Externí odkaz:
https://doaj.org/article/778c05f700f34d5cbdde9e7a39873011
Autor:
Wen-jin Chen, Ke-qin Dong, Xiu-wu Pan, Si-shun Gan, Da Xu, Jia-xin Chen, Wei-jie Chen, Wen-yan Li, Yu-qi Wang, Wang Zhou, Brian Rini, Xin-gang Cui
Publikováno v:
Cell Death and Disease, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Tumor growth, metastasis and therapeutic response are believed to be regulated by the tumor and its microenvironment (TME) in advanced renal cell carcinoma (RCC). However, the mechanisms underlying genomic, transcriptomic and epigenetic alte
Externí odkaz:
https://doaj.org/article/d2a358035a5a4a40aeec5e85972cefbd
Autor:
Wen-jin Chen, Hao Cao, Jian-wei Cao, Li Zuo, Fa-jun Qu, Da Xu, Hao Zhang, Hai-yi Gong, Jia-xin Chen, Jian-qing Ye, Si-shun Gan, Wang Zhou, Da-wei Zhu, Xiu-Wu Pan, Xin-gang Cui
Publikováno v:
Cell Death and Disease, Vol 13, Iss 1, Pp 1-14 (2022)
Abstract Non-clear renal cell carcinomas (nccRCCs) are less frequent in kidney cancer with histopathological heterogeneity. A better understanding of the tumor biology of nccRCC can provide more effective treatment paradigms for different subtypes. T
Externí odkaz:
https://doaj.org/article/cb6fa662dd4e457ab9e5f8192511f2ec
Autor:
Xiu-wu Pan, Da Xu, Wen-jin Chen, Jia-xin Chen, Wei-jie Chen, Jian-qing Ye, Si-shun Gan, Wang Zhou, Xu Song, Lei Shi, Xin-gang Cui
Publikováno v:
Cancer Cell International, Vol 21, Iss 1, Pp 1-16 (2021)
Abstract Background The benefit of targeted therapy for renal cell carcinoma (RCC) is largely crippled by drug resistance. Rapid disease progression and poor prognosis occur in patients with drug resistance. New treatments demand prompt exploration f
Externí odkaz:
https://doaj.org/article/cf0d4c2cd27f4242bee882c5c88df71f
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Ample evidence indicates that the development and progression of renal cell carcinoma (RCC) are complex pathological processes involving interactions between tumor cells, immune cells and stromal components. Tumor infiltrated immune cells determine w
Externí odkaz:
https://doaj.org/article/eaa325681c3f46f488ad53a96a3a4e64
Publikováno v:
Balkan Medical Journal, Vol 38, Iss 4, Pp 212-221 (2021)
Externí odkaz:
https://doaj.org/article/4a62a2a304e24fa4b2099806346f2c8b