Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Wen-Jia Lei"'
Autor:
Wen-Jia Lei, Fan Zhang, Meng-Die Li, Fan Pan, Li-Jun Ling, Jiang-Wen Lu, Leslie Myatt, Kang Sun, Wang-Sheng Wang
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract Background Parturition is an inflammation process. Exaggerated inflammatory reactions in infection lead to preterm birth. Although nuclear factor kappa B (NF-κB) has been recognized as a classical transcription factor mediating inflammatory
Externí odkaz:
https://doaj.org/article/0d0b45c7fd6e4b54b5c68f472d3c4d31
Autor:
Li-Jun Ling, Qiong Zhou, Fan Zhang, Wen-Jia Lei, Meng-Die Li, Jiang-Wen Lu, Wang-Sheng Wang, Kang Sun, Hao Ying
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionFetal membrane inflammation is an integral event of parturition. However, excessive pro-inflammatory cytokines can impose threats to the fetus. Coincidentally, the fetal membranes express abundant 11β-hydroxysteroid dehydrogenase 1 (11β
Externí odkaz:
https://doaj.org/article/f39ad715e64c4e598f688194a31d1cf0
Autor:
Meng-Die Li, Jiang-Wen Lu, Fan Zhang, Wen-Jia Lei, Fan Pan, Yi-Kai Lin, Li-Jun Ling, Leslie Myatt, Wang-Sheng Wang, Kang Sun
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Hyalectan cleavage may play an important role in extracellular matrix remodeling. However, the proteolytic enzyme responsible for hyalectan degradation for fetal membrane rupture at parturition remains unknown. Here, we reveal that versican
Externí odkaz:
https://doaj.org/article/9c6cd79e20e2466fae53894cbfa13b45
Publikováno v:
Molecular Medicine, Vol 29, Iss 1, Pp 1-16 (2023)
Abstract Background Inflammation of the fetal membranes is an indispensable event of labor onset at both term and preterm birth. Interleukin-33 (IL-33) is known to participate in inflammation via ST2 (suppression of tumorigenicity 2) receptor as an i
Externí odkaz:
https://doaj.org/article/a2a210539d16458da5b43784f30e6859
Autor:
Wang-Sheng Wang, Yi-Kai Lin, Fan Zhang, Wen-Jia Lei, Fang Pan, Ya-Nan Zhu, Jiang-Wen Lu, Chu-Yue Zhang, Qiong Zhou, Hao Ying, Kang Sun
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-18 (2022)
Abstract Background The human amnion is an intrauterine tissue which is involved in the initiation of parturition. In-depth understanding of gene expression signatures of individual cell types in the amnion with respect to membrane rupture at parturi
Externí odkaz:
https://doaj.org/article/ba4a299102c348f3ab48c711d2a9cbc0
Autor:
Xiao-tian Ni, Wang-sheng Wang, Yun Liu, Yi-kai Lin, Fan Zhang, Wen-jia Lei, Li-jun Ling, Fan Pan, Ya-nan Zhu, Meng-die Li, Tao Duan, Ming Liu, Kang Sun
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
BackgroundBradykinin (BK) and its biologically active metabolite des-Arg9 bradykinin (DABK) play a pivotal role in inflammation. Since chorioamnionitis is the leading cause of preterm birth and prostaglandin E2 (PGE2) derived from the amnion is key t
Externí odkaz:
https://doaj.org/article/af78f131cd474784bf7f6859cd743417
Autor:
Sun, Fan Zhang, Jiang-Wen Lu, Wen-Jia Lei, Meng-Die Li, Fan Pan, Yi-Kai Lin, Wang-Sheng Wang, Kang
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 13; Pages: 10881
Inflammation of the fetal membranes is an indispensable event of parturition, with increasing prostaglandin E2 (PGE2) synthesis as one of the ultimate products that prime labor onset. In addition to PGE2, the fetal membranes also boast a large capaci
Autor:
Jiang-Wen Lu, Wen-Jia Lei, Li-Jun Ling, Lu-Yao Wang, Yi-Kai Lin, Fan Zhang, Meng-Die Li, Fan Pan, Wang-Sheng Wang, Kang Sun
Publikováno v:
Endocrinology. 163
Fetal membrane activation is seen as being one of the crucial triggering components of human parturition. Increased prostaglandin E2 (PGE2) production, a common mediator of labor onset in virtually all species, is recognized as one of the landmark ev
Autor:
Wen-Jia Lei1, Miao Fan2, Mei-Lian Wang3,4, Yu Wang1, Wei Sun1, Xue Sun1, Ying Zhang1 baogoubei@hotmail.com, Lei, Wenjia5 (AUTHOR), Fan, Miao2 (AUTHOR), Wang, Meilian6 (AUTHOR), Wang, Yu5 (AUTHOR), Sun, Wei5 (AUTHOR), Sun, Xue5 (AUTHOR), Zhang, Ying5 (AUTHOR)
Publikováno v:
Medical Ultrasonography. Jun2018, Vol. 20 Issue 2, p213-220. 8p.