Zobrazeno 1 - 10
of 163
pro vyhledávání: '"Wen-I Liao"'
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-15 (2023)
Abstract Background The dysregulation of local circadian clock has been implicated in the pathogenesis of a broad spectrum of diseases. However, the pathophysiological role of intrinsic circadian clocks Rev-Erbα in ischemia-reperfusion (IR)-induced
Externí odkaz:
https://doaj.org/article/f44da4751f594f72b5e635fb11c22d30
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-17 (2020)
Abstract Background It is well known that ventilation with high volume or pressure may damage healthy lungs or worsen injured lungs. Melatonin has been reported to be effective in animal models of acute lung injury. Melatonin exerts its beneficial ef
Externí odkaz:
https://doaj.org/article/2bf21bc4bcef47dda3c61928d43594a0
Publikováno v:
Nutrients, Vol 14, Iss 24, p 5231 (2022)
A high fiber diet (HFD) and dietary supplementation with acetate have been reported to have beneficial effects in a variety of diseases. We investigated the effects of a HFD and acetate supplementation on the gut microbiota and hyperoxia-induced acut
Externí odkaz:
https://doaj.org/article/4912d1a653df4a2fb936665748b4701b
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Protease-activated receptor (PAR)-1 is a thrombin-activated receptor that plays an essential role in ischemia/reperfusion (IR)-induced acute inflammation. PAR-1 antagonists have been shown to alleviate injuries in various IR models. However, the effe
Externí odkaz:
https://doaj.org/article/1e3098cce12e4faab9909e462ba425d5
Autor:
Shih-En Tang, Wen-I Liao, Hsin-Ping Pao, Chin-Wang Hsu, Shu-Yu Wu, Kun-Lun Huang, Shi-Jye Chu
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: Poloxamer 188 (P188) possesses anti-inflammatory properties and can help to maintain plasma membrane function. P188 has been reported to exert beneficial effects in the treatment of various disorders. However, the effects of P188 in ische
Externí odkaz:
https://doaj.org/article/6b22c87cf2714b51a5f853e3f7ec580e
Autor:
Chih-Jen Yang, Chi-Hsiang Chung, Sy-Jou Chen, Wen-I Liao, Yi-Da Tsai, Jen-Chun Wang, Wu-Chien Chien
Publikováno v:
Journal of Medical Sciences, Vol 39, Iss 2, Pp 74-80 (2019)
Background: Ulcerative colitis (UC) is an immune-mediated inflammatory disease that is associated with an increased incidence of cardiovascular events. Several inflammatory mechanisms associated with the pathogenesis of UC are involved in the initiat
Externí odkaz:
https://doaj.org/article/8d029d9d894b45e1be9ade81886a4bcb
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Background: 2-Methoxyestradiol (2ME), a natural 17-β estradiol metabolite, is a potent anti-inflammatory agent, but its effect on ischemia/reperfusion (IR)-induced acute lung inflammation remains unknown. Annexin A1 (AnxA1), a glucocorticoid-regulat
Externí odkaz:
https://doaj.org/article/d0713ab3775b465b8cb8fc13c9705d29
Publikováno v:
Frontiers in Physiology, Vol 10 (2020)
BackgroundPrevious investigations reveal that BTP2, a store-operated calcium channel blocker, has protective and anti-inflammatory properties in multiple inflammatory diseases. This study investigates whether BTP2 can protect against decompression si
Externí odkaz:
https://doaj.org/article/424c5c4d21fd4577a7ff02cf6619a997
Autor:
Geng-Chin Wu, Wen-I Liao, Shu-Yu Wu, Hsin-Ping Pao, Shih-En Tang, Min-Hui Li, Kun-Lun Huang, Shi-Jye Chu
Publikováno v:
Respiratory Research, Vol 18, Iss 1, Pp 1-12 (2017)
Abstract Background Emerging evidence reveals that nicotinamide phosphoribosyltransferase (NAMPT) has a significant role in the pathophysiology of the inflammatory process. NAMPT inhibition has a beneficial effect in the treatment of a variety of inf
Externí odkaz:
https://doaj.org/article/9f9c1462443d46ceba775dc3549ce3cb
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Background: Increasing evidence suggests that Fbxo3 signaling has an important impact on the pathophysiology of the inflammatory process. Fbxo3 protein inhibition has reduced cytokine-driven inflammation and improved disease severity in animal model
Externí odkaz:
https://doaj.org/article/2559dabb552549648608d2c20dbb0361