Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Wen-He Zhang"'
Autor:
Jia-Xiang Lv, Ya-Qi Ding, Chen-Ming Huang, Ling-Ling Guo, Jia-Li Fang, Xian Jia, Wen-He Zhang, Song You, Bin Qin
Publikováno v:
Pharmaceutical Fronts, Vol 04, Iss 03, Pp e121-e135 (2022)
Abstract Multiple stereoisomers can be found when a substance contains chiral carbons in its chemical structure. To obtain the desired stereoisomers, asymmetric synthesis was proposed in the 1970s and developed rapidly at the beginning of this centu
Externí odkaz:
https://doaj.org/article/93f92291150c40d7bf2c768d91bfee88
Autor:
Biao Yu, Wen-He Zhang, Gong-Li Tang, Juan Zhao, Wen-Jia Kang, Fei Wang, Shengyang Wang, Hai-Xue Pan
Publikováno v:
Journal of the American Chemical Society. 142:5996-6000
Miharamycins are peptidyl nucleoside antibiotics with a unique branched C9 pyranosyl amino acid core and a rare 2-aminopurine moiety. Inactivation of 19 genes in the biosynthetic gene cluster and identification of several unexpected intermediates sug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8028f93a44c92e5f693cf3fe5aab0806
https://doi.org/10.1021/jacs.0c01778
https://doi.org/10.1021/jacs.0c01778
Publikováno v:
Organic letters. 23(22)
The biochemical elucidation of the early biosynthetic pathways of miharamycins and amipurimycin revealed the roles of several enzymes, which include GMP hydrolase, represented by MihD/ApmD, and hypothetical proteins, MihI/ApmI, unexpectedly exhibitin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b14096f8d1a2374848ee01cda96c502f
https://pubmed.ncbi.nlm.nih.gov/34747180
https://pubmed.ncbi.nlm.nih.gov/34747180
Publikováno v:
Organic Letters; 11/19/2021, Vol. 23 Issue 22, p8761-8765, 5p
Sequential conformation changes of chinese hamster ovary dihydrofolate reductase at its active sites
Publikováno v:
Protein and peptide letters. 12(5)
The local fluorescence probes, 2-(p-toluidino)-6-naphthalenesulfonic acid (TNS) and NADPH were employed to detect urea-induced conformation changes at each active site of dihydrofolate reductase (DHFR), respectively. The results indicate that local c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c665df3108a2fd2fc5cdfab0dd482b1
https://pubmed.ncbi.nlm.nih.gov/16029162
https://pubmed.ncbi.nlm.nih.gov/16029162
Publikováno v:
Chinese Journal of Agricultural Biotechnology; Apr2003, Vol. 1 Issue 1, p55-59, 5p