Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Wen-He Huang"'
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
ObjectiveTo develop a deep learning (DL) model for predicting axillary lymph node (ALN) metastasis using dynamic ultrasound (US) videos in breast cancer patients.MethodsA total of 271 US videos from 271 early breast cancer patients collected from Xia
Externí odkaz:
https://doaj.org/article/ab4d249b9ec140809a182b76c0ba85c6
Autor:
Yong‐Qu Zhang, Wan‐Ling Liu, Xiang‐Jie Luo, Jun‐Peng Shi, Yun‐Zhu Zeng, Wei‐Ling Chen, Wen‐He Huang, Yuan‐Yuan Zhu, Wen‐Liang Gao, Rong‐Hui Li, Zi‐He Ming, Li‐Xin Zhang, Rui‐Qin Yang, Jia‐Zheng Wang, Guo‐Jun Zhang
Publikováno v:
Advanced Science, Vol 10, Iss 10, Pp n/a-n/a (2023)
Abstract Breast‐conserving surgery (BCS) is the predominant treatment approach for initial breast cancer. However, due to a lack of effective methods evaluating BCS margins, local recurrence caused by positive margins remains an issue. Accordingly,
Externí odkaz:
https://doaj.org/article/2a21ea7b36724f4582732c1f37c4f154
Autor:
Yi‐Yang Gao, Rui‐Qin Yang, Kang‐Liang Lou, Yong‐Ying Dang, Yuan‐Yuan Dong, Yue‐Yang He, Wen‐He Huang, Min Chen, Guo‐Jun Zhang
Publikováno v:
MedComm, Vol 3, Iss 3, Pp n/a-n/a (2022)
Abstract The CDK4/6‐Rb axis is a crucial target of cancer therapy and several selective inhibitors of it have been approved for clinical application. However, current therapeutic efficacy evaluation mostly relies on anatomical imaging, which cannot
Externí odkaz:
https://doaj.org/article/f0bc609e9005448ea8d9786ef2ea1125
Autor:
Yong-Qu Zhang, Yuan-Ke Liang, Yang Wu, Min Chen, Wei-Ling Chen, Rong-Hui Li, Yun-Zhu Zeng, Wen-He Huang, Jun-Dong Wu, De Zeng, Wen-Liang Gao, Chun-Fa Chen, Hao-Yu Lin, Rui-Qin Yang, Jiang-Wen Zhu, Wan-Ling Liu, Jing-Wen Bai, Min Wei, Xiao-Long Wei, Guo-Jun Zhang
Publikováno v:
Cell Death and Disease, Vol 12, Iss 6, Pp 1-16 (2021)
Abstract Notch receptors (Notch1–4) play critical roles in tumorigenesis and metastasis of malignant tumors, including breast cancer. Although abnormal Notch activation is related to various tumors, the importance of single receptors and their mech
Externí odkaz:
https://doaj.org/article/16de3419a8a24638b1ca92d9bab9d292
Autor:
Rui‐Qin Yang, Pei‐Yuan Wang, Kang‐Liang Lou, Yong‐Ying Dang, Hai‐Na Tian, Yang Li, Yi‐Yang Gao, Wen‐He Huang, Yong‐Qu Zhang, Xiao‐Long Liu, Guo‐Jun Zhang
Publikováno v:
Advanced Science, Vol 9, Iss 12, Pp n/a-n/a (2022)
Abstract Positive resection margin frequently exists in breast‐conserving treatment (BCT) of early‐stage breast cancer, and insufficient therapeutic efficacy is common during radiotherapy (RT) in advanced breast cancer patients. Moreover, a multi
Externí odkaz:
https://doaj.org/article/9768a2516cd245de922428249d0a6f1c
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Background: In the latest rankings, breast cancer ranks first in incidence and fifth in mortality among female malignancies worldwide. Early diagnosis and treatment can improve the prognosis and prolong the survival of breast cancer (BC) patients. Th
Externí odkaz:
https://doaj.org/article/be43ea659922482cbd1f8182465cd56d
Autor:
Jun‐Dong Wu, Zun Wang, Huan‐Cheng Zeng, Li‐Fang He, Yong‐Qu Zhang, Guang‐Sheng Huang, Fan Zhang, Xiao‐Long Wei, Wen‐He Huang, Guo‐Jun Zhang
Publikováno v:
MedComm, Vol 1, Iss 2, Pp 211-218 (2020)
Abstract Axillary reverse mapping (ARM) is a technique to identify arm lymphatic drainage during axillary lymph node dissection (ALND). This study compared the feasibility of ARM using indocyanine green (ICG) or methylene blue (MB), and accessed the
Externí odkaz:
https://doaj.org/article/8ceb58bdc5a8409a9534475774e293b1
Autor:
Yong-Qu Zhang, Fan Zhang, Yun-Zhu Zeng, Min Chen, Wen-He Huang, Jun-Dong Wu, Wei-Ling Chen, Wen-Liang Gao, Jing-Wen Bai, Rui-Qin Yang, Huan-Cheng Zeng, Xiao-Long Wei, Guo-Jun Zhang
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
PurposeThe basic helix-loop-helix transcription factor (bHLH) transcription factor Twist1 plays a key role in embryonic development and tumorigenesis. p53 is a frequently mutated tumor suppressor in cancer. Both proteins play a key and significant ro
Externí odkaz:
https://doaj.org/article/97a73eaef83a410692141dadcc8b5a22
Autor:
Zun Wang, Min Chen, Jing-Jing Liu, Rong-He Chen, Qian Yu, Gui-Mei Wang, Li-Ming Nie, Wen-He Huang, Guo-Jun Zhang
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
ObjectiveAchieving negative resection margin is critical but challenging in breast-conserving surgery. Fluorescence-guided surgery allows the surgeon to visualize the tumor bed in real-time and to facilitate complete resection. We envisioned that int
Externí odkaz:
https://doaj.org/article/a2a44ab766964748a67e5c82bed8ce7e
Autor:
Yong-Qu Zhang, Xiao-Long Wei, Yuan-Ke Liang, Wei-Ling Chen, Fan Zhang, Jing-Wen Bai, Si-Qi Qiu, Cai-Wen Du, Wen-He Huang, Guo-Jun Zhang
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135851 (2015)
Overexpression of Twist, a highly conserved basic helix-loop-helix transcription factor, is associated with epithelial-mesenchymal transition (EMT) and predicts poor prognosis in various kinds of cancers, including breast cancer. In order to further
Externí odkaz:
https://doaj.org/article/d30acbc63ea142f7a84eed7ed938c3a7