Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Wen-Gong Yu"'
Autor:
Jing Yang, Yan-Peng Wang, Wen-Gong Yu, Yu-Yao Guan, Prince Emmanuel Opoku Amponsah, Xian-Shuai Tang, Ying-Zi Sun, Lei Zheng
Publikováno v:
World Journal of Traditional Chinese Medicine, Vol 10, Iss 2, Pp 220-229 (2024)
Objective: The objective of this study was to explore the safety, efficacy, economy, and other aspects of frequently-used antitumor Chinese patent medicine injections through a comprehensive evaluation of evidence-based medical research to provide sc
Externí odkaz:
https://doaj.org/article/cbdbec1237844e1780c42f673913f9c8
Publikováno v:
Molecules, Vol 25, Iss 6, p 1314 (2020)
The deposition of aggregated human islet amyloid polypeptide (hIAPP) in the pancreas, that has been associated with β-cell dysfunction, is one of the common pathological features of patients with type 2 diabetes (T2D). Therefore, hIAPP aggregation i
Externí odkaz:
https://doaj.org/article/8fc0884c567b439d96649a814115e83b
Publikováno v:
Journal of the Marine Biological Association of the United Kingdom. 94:681-686
Renibacteriumsp. QD1, a bacteria strain capable of hydrolysing chitosan, was isolated from the homogenate of small crabs. An extracellular chitosanase, Csn-A, was purified from the QD1 fermentation broth. The enzyme was purified to homogeneity, with
Publikováno v:
Fish & Shellfish Immunology. 34:514-520
Vibrio anguillarum is the etiological agent of vibriosis, an aquaculture disease that affects a wide range of farmed fish. The genome of V. anguillarum contains five flagellin genes, i.e. flaA, flaB, flaC, flaD, and flaE. In this study, we analyzed t
Publikováno v:
International Journal of Radiation Biology. 86:1061-1069
Purpose: Purple sweet potato (PSP) pigments have been widely accepted as antioxidants but their radioprotective effect still remains unclear. In this study we investigated the effect of PSP pigment...
Publikováno v:
Journal of Neurochemistry. 111:441-451
Oxidative stress has long been linked to cell death in many neurodegenerative conditions. Treatment with antioxidants is a promising approach for slowing disease progression. In this study, we used the neuroblastoma SH-SY5Y cells as an in vitro model
Autor:
Michio Tomura, Wen-Gong Yu, Hyun-Jong Ahn, Motozo Yamashita, Yi-Fu Yang, Shiro Ono, Toshiyuki Hamaoka, Tetsu Kawano, Masaru Taniguchi, Yasuhiko Koezuka, Hiromi Fujiwara
Publikováno v:
The Journal of Immunology. 163:93-101
The balance between Th1 and Th2 development is determined by IL-4 and IL-12. While the role for CD4+ NK1.1+ T (NKT) cells in influencing this balance has been recognized based on their capacity to produce IL-4, it is unknown how IL-12 is produced in
Autor:
Hyun-Jong Ahn, Michio Tomura, Wen-Gong Yu, Masayuki Iwasaki, Woong-Ryeon Park, Toshiyuki Hamaoka, Hiromi Fujiwara
Publikováno v:
The Journal of Immunology. 161:5893-5900
While IL-12 is known to activate JAK2 and TYK2 and induce the phosphorylation of STAT4 and STAT3, little is known regarding how the activation of these signaling molecules is related to the biologic effects of IL-12. Using an IL-12-responsive T cell
Autor:
Makoto Ogawa, Hiromi Fujiwara, Takahiro Tsujimura, Jie Mu, Kazunari Umehara, Wen-Gong Yu, Toshiyuki Hamaoka
Publikováno v:
Journal of Leukocyte Biology. 62:450-457
Administration of recombinant interleukin-12 (rIL-12) into CSA1M fibrosarcoma-bearing mice results in complete regression of growing tumors. This tumor regression is associated with massive lymphoid cell infiltration to tumor sites and is completely
Autor:
Hiromi Fujiwara, Hiroshi Takenaka, Wen-Gong Yu, Tateki Tsutsui, Ryotaro Yoshida, Rishani Wijesuriya, Noriniko Yamamoto, Jie Mu, Toshiyuki Hamaoka, Steven H. Herrmann, Xu-Guang Tai, Makoto Ogowa, Jian-Ping Zou
Publikováno v:
International Immunology. 8:855-865
The present study investigates the molecular mechanisms by which IFN-gamma produced as a result of in vivo IL-12 administration exerts its anti-tumor effects. rIL-12 was administered three or five times into mice bearing CSA1M fibrosarcoma, OV-HM ova