Zobrazeno 1 - 10
of 551
pro vyhledávání: '"Wen-Chang Chang"'
Autor:
Chang-Han Chen, Hung-Wei Lin, Meng-Fang Huang, Chi-Wu Chiang, Kuen-Haur Lee, Nguyen Thanh Phuong, Zong-Yan Cai, Wen-Chang Chang, Ding-Yen Lin
Publikováno v:
BMC Molecular and Cell Biology, Vol 25, Iss 1, Pp 1-16 (2024)
Abstract Background Fas-associated factor 1 (FAF1) is a multidomain protein that interacts with diverse partners to affect numerous cellular processes. Previously, we discovered two Small Ubiquitin-like Modifier (SUMO)-interacting motifs (SIMs) withi
Externí odkaz:
https://doaj.org/article/425a48c56ec8479ab4f6de66536bde33
Autor:
Yung-Ching Chen, Ming-Jer Young, Hui-Ping Chang, Chia-Yu Liu, Chia-Chi Lee, Yau-Lin Tseng, Yi-Ching Wang, Wen-Chang Chang, Jan-Jong Hung
Publikováno v:
Oncogenesis, Vol 11, Iss 1, Pp 1-13 (2022)
Abstract Previous studies indicate that estrogen positively regulates lung cancer progression. Understanding the reasons will be beneficial for treating women with lung cancer in the future. In this study, we found that tumor formation was more signi
Externí odkaz:
https://doaj.org/article/a0ab8ee31dec4faa8f3e2a5926d35058
Autor:
Yu-Ting Tsai, Wei-Lun Lo, Pin-Yuan Chen, Chiung-Yuan Ko, Jian-Ying Chuang, Tzu-Jen Kao, Wen-Bing Yang, Kwang-Yu Chang, Chia-Yang Hung, Ushio Kikkawa, Wen-Chang Chang, Tsung-I. Hsu
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-17 (2022)
Abstract Background Sp1 is involved in the recurrence of glioblastoma (GBM) due to the acquirement of resistance to temozolomide (TMZ). Particularly, the role of Sp1 in metabolic reprogramming for drug resistance remains unknown. Methods RNA-Seq and
Externí odkaz:
https://doaj.org/article/41e5eb2931d64c3ea1398dfe091319be
Autor:
An-Chih Wu, Wen-Bin Yang, Kwang-Yu Chang, Jung-Shun Lee, Jing-Ping Liou, Ruei-Yuan Su, Siao Muk Cheng, Daw-Yang Hwang, Ushio Kikkawa, Tsung-I Hsu, Chih-Yang Wang, Wen-Chang Chang, Pin-Yuan Chen, Jian-Ying Chuang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-19 (2022)
Abstract Background Glioblastoma (GBM) is the most aggressive and lethal brain tumor. Although the histone deacetylase (HDAC)/transcription factor axis promotes growth in GBM, whether HDACs including HDAC6 are involved in modulating long non-coding R
Externí odkaz:
https://doaj.org/article/d9672530025d48d3b6d942240400f4bd
Autor:
Ming-Jer Young, Yung-Ching Chen, Shao-An Wang, Hui-Ping Chang, Wen-Bin Yang, Chia-Chi Lee, Chia-Yu Liu, Yau-Lin Tseng, Yi-Ching Wang, H. Sunny Sun, Wen-Chang Chang, Jan-Jong Hung
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-22 (2022)
Abstract Background Sp1, an important transcription factor, is involved in the progression of various cancers. Our previous studies have indicated that Sp1 levels are increased in the early stage of lung cancer progression but decrease during the lat
Externí odkaz:
https://doaj.org/article/d228509c4c3d440e80245ee03d7ed8bd
Autor:
Wen-Bin Yang, An-Chih Wu, Tsung-I Hsu, Jing-Ping Liou, Wei-Lun Lo, Kwang-Yu Chang, Pin-Yuan Chen, Ushio Kikkawa, Shung-Tai Yang, Tzu-Jen Kao, Ruei-Ming Chen, Wen-Chang Chang, Chiung-Yuan Ko, Jian-Ying Chuang
Publikováno v:
Cell Death and Disease, Vol 12, Iss 10, Pp 1-13 (2021)
Abstract DNA repair promotes the progression and recurrence of glioblastoma (GBM). However, there remain no effective therapies for targeting the DNA damage response and repair (DDR) pathway in the clinical setting. Thus, we aimed to conduct a compre
Externí odkaz:
https://doaj.org/article/0550dd11627c4cb1b510f29cabb3b452
Publikováno v:
Fermentation, Vol 9, Iss 4, p 366 (2023)
Methylglyoxal (MG) is a highly reactive dicarbonyl aldehyde and a major precursor of advanced glycation end products that result in oxidative stress. Graptopetalum paraguayense E. Walther (WGP) is a herbal medicine of Taiwan with the hepatoprotective
Externí odkaz:
https://doaj.org/article/85f3ccc0cd5f4757930ad21332299580
Publikováno v:
Foods, Vol 12, Iss 8, p 1584 (2023)
Black garlic has many beneficial effects, and it has a less spicy flavor. However, its aging conditions and related products still need to be further investigated. The present study aims to analyze the beneficial effects under different processing co
Externí odkaz:
https://doaj.org/article/90dac44d5d264eeeb900f562e50ba0a3
Autor:
Chih‐Yuan Ko, Yangming Martin Lo, Jian‐Hua Xu, Wen‐Chang Chang, Da‐Wei Huang, James Swi‐Bea Wu, Cho‐Hua Yang, Wen‐Chung Huang, Szu‐Chuan Shen
Publikováno v:
Food Science & Nutrition, Vol 9, Iss 5, Pp 2733-2742 (2021)
Abstract The occurrence of nonalcoholic fatty liver disease (NAFLD) is associated with type 2 diabetes mellitus (T2DM). The activation of nucleotide‐binding domain and leucine‐rich‐containing family, pyrin domain‐containing 3 (NLRP3) inflamma
Externí odkaz:
https://doaj.org/article/f335ca36275c42648bc719c2be191d56
Publikováno v:
Oncogenesis, Vol 10, Iss 1, Pp 1-15 (2021)
Abstract The metabolic changes in melanoma cells that are required for tumor metastasis have not been fully elucidated. In this study, we show that the increase in glucose uptake and mitochondrial oxidative phosphorylation confers metastatic ability
Externí odkaz:
https://doaj.org/article/eb98592bfb2349a98568eb8e2f961056