Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Wen-Cai Zhang"'
Autor:
Bin-Bin Zhang, Yi-Lin Zhao, Yan-Yu Lu, Ji-Hong Shen, Hui-Yong Li, Han-Xue Zhang, Xiao-Yue Yu, Wen-Cai Zhang, Gang Li, Zhan-Ying Han, Sen Guo, Xu-Tao Zhang
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Pathological cardiac hypertrophy is the primary cause of heart failure, yet its underlying mechanisms remain incompletely understood. Transmembrane protein 100 (TMEM100) plays a role in various disorders, such as nervous system disease, pain
Externí odkaz:
https://doaj.org/article/a166752f3b794a1392a154e1182a495a
Autor:
Guo-Song Jia1, Wen-Cai Zhang1, Yue Liang1, Xi-Han Liu1, Rhind, Nicholas2, Pidoux, Alison3, Brysch-Herzberg, Michael4 michael.bryschherzberg@hs-heilbronn.de, Li-Lin Du1,5 dulilin@nibs.ac.cn
Publikováno v:
G3: Genes | Genomes | Genetics. Apr2023, Vol. 13 Issue 4, p1-31. 31p.
Autor:
Bin-Bin Zhang, Lu Gao, Qin Yang, Yuan Liu, Xiao-Yue Yu, Ji-Hong Shen, Wen-Cai Zhang, Zhan-Ying Han, Shao-Ze Chen, Sen Guo
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-11 (2021)
Abstract Pathological myocardial hypertrophy is regulated by multiple pathways. However, its underlying pathogenesis has not been fully explored. The goal of this work was to elucidate the function of polypeptide N-acetylgalactosaminyltransferase 4 (
Externí odkaz:
https://doaj.org/article/8d9ec1d9022c41daab29f6a0aafa127b
Autor:
Ping Xu, Feng Zhang, Min-min Chang, Cheng Zhong, Cheng-Hong Sun, Hao-Ran Zhu, Jing-Chun Yao, Zhi-Zhong Li, Si-Tao Li, Wen-Cai Zhang, Guo-Dong Sun
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-16 (2021)
Abstract Background Immune cell infiltration and neuroinflammation are heavily associated with spinal cord injury (SCI). C-C motif chemokine ligand 2/C-C chemokine receptor type 2 (CCL2/CCR2) axis has been identified as a critical role player during
Externí odkaz:
https://doaj.org/article/88cc0d6c5bd24d5ebea7ee7eb446927c
Autor:
Fareesa Aftab, Alice Rodriguez-Fuguet, Luis Silva, Ikei S. Kobayashi, Jiao Sun, Katerina Politi, Elena Levantini, Wei Zhang, Susumu S. Kobayashi, Wen Cai Zhang
Publikováno v:
British Journal of Cancer. 128:1647-1664
Background Lung cancer cells overexpress mucin 1 (MUC1) and active subunit MUC1-CT. Although a peptide blocks MUC1 signalling, metabolites targeting MUC1 are not well studied. AICAR is a purine biosynthesis intermediate. Methods Cell viability and ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68bc85b63db63df520bb970e5f3412e4
https://doi.org/10.1038/s41416-023-02196-z
https://doi.org/10.1038/s41416-023-02196-z
Publikováno v:
iScience, Vol 23, Iss 2, Pp - (2020)
Summary: MicroRNA-34 (miR-34) is one of the major families of tumor suppressor miRNAs often lost in cancers. Delivery of miR-34a mimics to affected tumors as a therapeutic strategy has been tried in pre-clinical studies and in a phase I clinical tria
Externí odkaz:
https://doaj.org/article/e0b007c7d58d4a87b557ec68fa0886a1
Autor:
Wen Cai Zhang, Nicholas Skiados, Fareesa Aftab, Cerena Moreno, Luis Silva, Paul Joshua Anthony Corbilla, John M. Asara, Aaron N. Hata, Frank J. Slack
Publikováno v:
Cancer Gene Therapy. 29:1878-1894
In EGFR-mutant lung cancer, drug-tolerant persister cells (DTPCs) show prolonged survival when receiving EGFR tyrosine kinase inhibitor (TKI) treatments. They are a likely source of drug resistance, but little is known about how these cells tolerate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::461f519732b84aa11a629d52de1ac79d
https://doi.org/10.1038/s41417-022-00504-y
https://doi.org/10.1038/s41417-022-00504-y
Publikováno v:
Cancer Research Communications.
Recent preclinical studies have linked antidepressants (ADs) to their potential anticancer effects in multiple cancers, but the impact on lung cancer remains unclear. This meta-analysis examined the associations between ADs and lung cancer incidence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81ca7c918ffdb1ae547d60e5cf7e2b5d
https://doi.org/10.1158/2767-9764.crc-23-0003
https://doi.org/10.1158/2767-9764.crc-23-0003
Autor:
Wen Cai Zhang, Tan Min Chin, Henry Yang, Min En Nga, Declan Patrick Lunny, Edwin Kok Hao Lim, Li Li Sun, Yin Huei Pang, Yi Ning Leow, Shanneen Rossellini Y Malusay, Priscilla Xin Hui Lim, Jeravan Zili Lee, Benedict Jian Wei Tan, Ng Shyh-Chang, Elaine Hsuen Lim, Wan Teck Lim, Daniel Shao Weng Tan, Eng Huat Tan, Bee Choo Tai, Ross Andrew Soo, Wai Leong Tam, Bing Lim
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
miRNAs can function either as proto-oncogenes or tumour suppressors in several cancers; however their function in tumour initiating cells is unclear. Here, Zhang et al. show that tumour initiating cell-specific miR-1246 and miR-1290 promote lung canc
Externí odkaz:
https://doaj.org/article/a77285cd13d847d6a9987229f6e39d6d
Autor:
Wen-Cai Zhang, Yan-Ge Wang, Wen-Hui Wei, Xin Xiong, Kan-Ling Liu, Ding-Hang Wang, Xiao-Fan Hu, Yu-Dong Peng, Jing-Jing Wu, Long-Xian Cheng
Publikováno v:
Cellular Physiology and Biochemistry, Vol 38, Iss 6, Pp 2438-2451 (2016)
Background/Aims: Myeloid-derived suppressor cells (MDSCs) are increased in inflammatory and autoimmune disorders. This study aims to evaluate the significance of MDSCs in dilated cardiomyopathy (DCM) patients. Methods: In total, 42 newly hospitalized
Externí odkaz:
https://doaj.org/article/f281667b122f4a45b473da9b4b9cef90