Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Wen-Bing Chen"'
Autor:
Jie Huang, Yan-Yan Zhang, Yu-Yang Qiu, Shan Yao, Wan-Ting Qiu, Jin-Lin Peng, Yuan-Quan Li, Qiang-Long You, Cui-Hong Wu, Er-Jian Wu, Jin Wang, Yan-Ling Zhou, Yu-Ping Ning, Hong-Sheng Wang, Wen-Bing Chen, Bing-Jie Hu, Youtan Liu, Xiang-Dong Sun
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113905- (2024)
Summary: Motivation-driven mating is a basic affair for the maintenance of species. However, the underlying molecular mechanisms that control mating motivation are not fully understood. Here, we report that NRG1-ErbB4 signaling in the medial amygdala
Externí odkaz:
https://doaj.org/article/61d914530c4a4f569396c49faeeb745c
Autor:
Dongyan Ren, Bin Luo, Peng Chen, Lulu Yu, Mingtao Xiong, Zhiqiang Fu, Tian Zhou, Wen-Bing Chen, Erkang Fei
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Background Dendritic spines are the sites of excitatory synapses on pyramidal neurons, and their development is crucial for neural circuits and brain functions. The spine shape, size, or number alterations are associated with neurological di
Externí odkaz:
https://doaj.org/article/15a02c119e6b4ba6845b2c86bd578156
Autor:
Shan Yao, Min-Dong Xu, Ying Wang, Shen-Ting Zhao, Jin Wang, Gui-Fu Chen, Wen-Bing Chen, Jian Liu, Guo-Bin Huang, Wen-Juan Sun, Yan-Yan Zhang, Huan-Li Hou, Lei Li, Xiang-Dong Sun
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
The role of glycolysis in depression is unclear. Here the authors report a glycolytic deficit under social stress and demonstrate that astrocytic LDHA affects neuronal excitability and depressive-like behaviours via lactate homeostasis in mice.
Externí odkaz:
https://doaj.org/article/d2df2840bdd647cd8bb7bb8ce72c67aa
Publikováno v:
Cell & Bioscience, Vol 10, Iss 1, Pp 1-8 (2020)
Abstract Background Fear is an adaptive response across species in the face of threatening cues. It can be either innate or learned through postnatal experience. We have previously shown that genetic deletion of both Rap1a and Rap1b, two isoforms of
Externí odkaz:
https://doaj.org/article/65243b20fb8c46768c1ba5264b9bb9be
Autor:
Tian-Kun Hui, Xin-Sheng Lai, Xia Dong, Hongyang Jing, Ziyang Liu, Erkang Fei, Wen-Bing Chen, Shunqi Wang, Dongyan Ren, Suqi Zou, Hai-Tao Wu, Bing-Xing Pan
Publikováno v:
Biology, Vol 10, Iss 6, p 452 (2021)
Low-density lipoprotein receptor-related protein 4 (Lrp4) is a critical protein involved in the Agrin-Lrp4-MuSK signaling pathway that drives the clustering of acetylcholine receptors (AChRs) at the neuromuscular junction (NMJ). Many studies have sho
Externí odkaz:
https://doaj.org/article/e216fe0d372a43c8bd97492727ffa0d8
Publikováno v:
Biology, Vol 9, Iss 11, p 359 (2020)
Metformin, a first-line drug for type 2 diabetes mellitus (T2DM), has been found to reduce depressive symptoms in patients with comorbid depression and other diseases. However, it is largely unclear how metformin ameliorates depressive-like behaviors
Externí odkaz:
https://doaj.org/article/ab59fb1efedc4a7a8fc7a9d909b040d8
Publikováno v:
Brain Sciences, Vol 10, Iss 10, p 706 (2020)
Metformin (Met) is a first-line drug for type 2 diabetes mellitus (T2DM). Numerous studies have shown that Met exerts beneficial effects on a variety of neurological disorders, including Alzheimer’s disease (AD), Parkinson’s disease (PD) and Hunt
Externí odkaz:
https://doaj.org/article/aaf905622e8a4fbc85a772ea7afe10dc
Autor:
Wen-bing Chen, 陳文斌
95
C9orf75 and H3P were identified as a PP1-binding protein by yeast two-hybridization system. Both proteins contain one PP1-binding motif. C9orf75 consists of 136 amino acids, while H3P contains 186 amino acids. Although C9orf75 and H3P have be
C9orf75 and H3P were identified as a PP1-binding protein by yeast two-hybridization system. Both proteins contain one PP1-binding motif. C9orf75 consists of 136 amino acids, while H3P contains 186 amino acids. Although C9orf75 and H3P have be
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/61515034366842774095
Autor:
Dong Lin, Luhui Li, Wen-Bing Chen, Jiang Chen, Dongyan Ren, Zhi-Heng Zheng, Changqin Zhao, Yanzi Zhong, Bin Luo, Hongyang Jing, Peng Chen, Suqi Zou, Xinsheng Lai, Tian Zhou, Ning Ding, Lei Li, Bing-Xing Pan, Erkang Fei
Publikováno v:
Molecular Psychiatry. 28:908-918
Histidine phosphorylation (pHis), occurring on the histidine of substrate proteins, is a hidden phosphoproteome that is poorly characterized in mammals. LHPP (phospholysine phosphohistidine inorganic pyrophosphate phosphatase) is one of the histidine
Autor:
Han-Qing Pan, Xiao-Xuan Liu, Ye He, Jin Zhou, Cai-Zhi Liao, Wen-Jie You, Si-Ying Jiang, Xia Qin, Wen-Bing Chen, Er-Kang Fei, Wen-Hua Zhang, Bing-Xing Pan
Publikováno v:
The Journal of Neuroscience. 42:5755-5770