Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Wen Yih Aw"'
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Over the past decade, advances in microfabrication and biomaterials have facilitated the development of microfluidic tissue and organ models to address challenges with conventional animal and cell culture systems. These systems have largely been deve
Externí odkaz:
https://doaj.org/article/d15fa325584b4d82b6ad0211365a19a5
Autor:
Ulrike Beckert, Wen Yih Aw, Heike Burhenne, Lisa Försterling, Volkhard Kaever, Lisa Timmons, Roland Seifert
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72569 (2013)
Adenosine 3', 5'-cyclic monophosphate (cAMP) and guanosine 3', 5'-cyclic monophosphate (cGMP) are well-studied second messengers that transmit extracellular signals into mammalian cells, with conserved functions in various other species such as Caeno
Externí odkaz:
https://doaj.org/article/2a6431a1ee184bcc860fffceadfa6b00
Autor:
Ulrike Beckert, Wen Yih Aw, Heike Burhenne, Lisa Försterling, Volkhard Kaever, Lisa Timmons, Roland Seifert
Publikováno v:
PLoS ONE, Vol 8, Iss 11 (2013)
Externí odkaz:
https://doaj.org/article/9515400ee20a4ae9b1303fcd4bb5b144
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50191 (2012)
Organisms used as model genomics systems are maintained as isogenic strains, yet evidence of sequence differences between independently maintained wild-type stocks has been substantiated by whole-genome resequencing data and strain-specific phenotype
Externí odkaz:
https://doaj.org/article/cd41aed556fb4d4dafb974892ddaa28b
Autor:
Elizabeth L. Doherty, Wen Yih Aw, Emily C. Warren, Max Hockenberry, Chloe P. Whitworth, Grace Krohn, Stefanie Howell, Brian O. Diekman, Wesley R. Legant, Hadi Tavakoli Nia, Anthony J. Hickey, William J. Polacheck
Publikováno v:
Acta Biomaterialia.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cca37e28c6c6044fe50959591f4e9355
https://doi.org/10.1016/j.actbio.2023.05.015
https://doi.org/10.1016/j.actbio.2023.05.015
Autor:
Wen Yih Aw, Crescentia Cho, Hao Wang, Anne Hope Cooper, Elizabeth L. Doherty, David Rocco, Stephanie A. Huang, Sarah Kubik, Chloe P. Whitworth, Ryan Armstrong, Anthony J. Hickey, Boyce Griffith, Matthew L. Kutys, Julie Blatt, William J. Polacheck
Publikováno v:
Science advances, vol 9, iss 7
Somatic activating mutations of PIK3CA are associated with development of vascular malformations (VMs). Here, we describe a microfluidic model of PIK3CA -driven VMs consisting of human umbilical vein endothelial cells expressing PIK3CA activating mut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23413f8820fcb336982c85d7df8923a6
https://escholarship.org/uc/item/3863j9kv
https://escholarship.org/uc/item/3863j9kv
Autor:
Elizabeth L. Doherty, Wen Yih Aw, Emily C. Warren, Max Hockenberry, Grace Krohn, Stefanie Howell, Brian O. Diekman, Wesley R. Legant, Hadi Tavakoli Nia, Anthony J. Hickey, William J. Polacheck
Vascular Ehlers-Danlos Syndrome (vEDS) is a rare autosomal dominant disease caused by mutations in theCOL3A1gene, which renders patients susceptible to aneurysm and arterial dissection and rupture. To determine the role ofCOL3A1variants in the bioche
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::615490bf5fe86dafa1d1037bcc77edc5
https://doi.org/10.1101/2022.10.16.512399
https://doi.org/10.1101/2022.10.16.512399
Autor:
Wen Yih Aw, Crescentia Cho, Hao Wang, Anne Hope Cooper, Elizabeth L. Doherty, David Rocco, Stephanie A. Huang, Sarah Kubik, Chloe P. Whitworth, Ryan Armstrong, Anthony J. Hickey, Boyce Griffith, Matthew L. Kutys, Julie Blatt, William J. Polacheck
Somatic activating mutations of PIK3CA are associated with the development of vascular malformations (VMs). Here, we describe a microfluidic model of PIK3CA-driven VMs consisting of human umbilical vein endothelial cells (HUVECs) expressing PIK3CA ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::583f01e59450e8d9a0fdbb9e9afebc3b
https://doi.org/10.1101/2022.09.03.506415
https://doi.org/10.1101/2022.09.03.506415
Autor:
Lisa E.L. Romano, Wen Yih Aw, Kathryn M. Hixson, Tatiana V. Novoselova, Tammy M. Havener, Stefanie Howell, Bonnie Taylor-Blake, Charlotte L. Hall, Lei Xing, Josh Beri, Suran Nethisinghe, Laura Perna, Abubakar Hatimy, Ginevra Chioccioli Altadonna, Lee M. Graves, Laura E. Herring, Anthony J. Hickey, Konstantinos Thalassinos, J. Paul Chapple, Justin M. Wolter
Publikováno v:
Cell Reports. 41:111580
Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a childhood-onset cerebellar ataxia caused by mutations in SACS, which encodes the protein sacsin. Cellular ARSACS phenotypes include mitochondrial dysfunction, intermediate filame
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1efacf47940593ba8d8b563e29d0f497
https://doi.org/10.1016/j.celrep.2022.111580
https://doi.org/10.1016/j.celrep.2022.111580
Autor:
Anthony J. Hickey, Suran Nethisinghe, Abubakar Hatimy, Lei Xing, Charlotte L. Hall, Laura Perna, Wen Yih Aw, Stefanie D. Howell, Laura E. Herring, Tammy M. Havener, Josh Beri, Lee M. Graves, Ginevra Chioccioli Altadonna, Konstantinos Thalassinos, Justin M. Wolter, Kathryn M. Hixson, J. Paul Chapple, Lisa E.L. Romano, Tatiana V. Novoselova
Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is caused by mutations in SACS, which manifest as a childhood-onset cerebellar ataxia. Cellular ARSACS phenotypes include mitochondrial dysfunction, intermediate filament (IF) disorga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ddf55dbd3a1a1167cccb374e46fa9a4
https://doi.org/10.1101/2021.08.20.456807
https://doi.org/10.1101/2021.08.20.456807