Zobrazeno 1 - 10
of 430
pro vyhledávání: '"Wen W. Ma"'
Autor:
Neil J. Clendeninn, Prabhu Rajagopalan, Michael Jeffers, Ronald L. Dubowy, Li-Tain Yeh, Zancong Shen, Jeffrey N. Miner, Cory Iverson, Beth Sheedy, Wen W. Ma, Grace K. Dy, Ramesh K. Ramanathan, Glen J. Weiss, Karl D. Lewis, Lia Gore, S. Gail Eckhardt, Diane P. Leffingwell, Alex A. Adjei, Daniel D. Von Hoff, Colin D. Weekes
Purpose: To evaluate the safety, pharmacokinetics, and pharmacodynamics of BAY 86-9766, a selective, potent, orally available, small-molecule allosteric inhibitor of mitogen-activated protein kinase 1/2 in patients with advanced solid tumors.Experime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15dee10b1d3e60f3bddbcf748ba9c9fa
https://doi.org/10.1158/1078-0432.c.6521624
https://doi.org/10.1158/1078-0432.c.6521624
Autor:
Neil J. Clendeninn, Prabhu Rajagopalan, Michael Jeffers, Ronald L. Dubowy, Li-Tain Yeh, Zancong Shen, Jeffrey N. Miner, Cory Iverson, Beth Sheedy, Wen W. Ma, Grace K. Dy, Ramesh K. Ramanathan, Glen J. Weiss, Karl D. Lewis, Lia Gore, S. Gail Eckhardt, Diane P. Leffingwell, Alex A. Adjei, Daniel D. Von Hoff, Colin D. Weekes
Table S1: Dose-limiting toxicities; Table S2:Multiple-dose pharmacokinetic parameters (geometric mean (%CV) of BAY 86-9766 and metabolite M17 on Course 1, Day 22 (representing exposure after 15 days of continuous dosing) for once-daily dosing cohorts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::645195f61f0c767c06b724819cf4f1ab
https://doi.org/10.1158/1078-0432.22449329.v1
https://doi.org/10.1158/1078-0432.22449329.v1
Autor:
Neil J. Clendeninn, Prabhu Rajagopalan, Michael Jeffers, Ronald L. Dubowy, Li-Tain Yeh, Zancong Shen, Jeffrey N. Miner, Cory Iverson, Beth Sheedy, Wen W. Ma, Grace K. Dy, Ramesh K. Ramanathan, Glen J. Weiss, Karl D. Lewis, Lia Gore, S. Gail Eckhardt, Diane P. Leffingwell, Alex A. Adjei, Daniel D. Von Hoff, Colin D. Weekes
Legend for supplementary figure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4075ee0a6ba696a2cc8a2e2623ba5399
https://doi.org/10.1158/1078-0432.22449335.v1
https://doi.org/10.1158/1078-0432.22449335.v1
Autor:
Neil J. Clendeninn, Prabhu Rajagopalan, Michael Jeffers, Ronald L. Dubowy, Li-Tain Yeh, Zancong Shen, Jeffrey N. Miner, Cory Iverson, Beth Sheedy, Wen W. Ma, Grace K. Dy, Ramesh K. Ramanathan, Glen J. Weiss, Karl D. Lewis, Lia Gore, S. Gail Eckhardt, Diane P. Leffingwell, Alex A. Adjei, Daniel D. Von Hoff, Colin D. Weekes
Treatment schema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a906ec27133370e1ec606fb43c97986
https://doi.org/10.1158/1078-0432.22449332
https://doi.org/10.1158/1078-0432.22449332
Autor:
Adam, Kotowski, Wen W, Ma
Publikováno v:
Journal of gastrointestinal oncology. 2(2)
Pancreas cancer has a grave prognosis and treatment options remain limited despite advancement in anti-cancer chemotherapeutics. This review provides an overview of the emerging therapies for pancreas cancer, focusing on novel signal transduction inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e24a83ca773de47f3f7ad3f659f12547
https://pubmed.ncbi.nlm.nih.gov/22811835
https://pubmed.ncbi.nlm.nih.gov/22811835
Autor:
Sylwia Ammoun, Epie Boven, Ana R. Quesada, Ajay Rana, Natasha Kyprianou, H. Evans, Laura Vroling, Teresa Calimeri, Theodora Kerenidi, Maria Teresa Di Martino, Malay Chatterjee, Wen W. Ma, C. Oliver Hanemann, Ellen Kossoff, Pierfrancesco Tassone, Paola Neri, Oliver Stoeltzing, Anupam Bishayee, Stewart G. Martin, Basabi Rana, Christian Moser, Gustavo Jacob Lourenço, Astrid A.M. van der Veldt, Miguel Ángel Medina, Renata Longo, Martijn R. Meijerink, Gabriele L. Gasparini, José Augusto Rinck, Joanne Collazo, Kostas Syrigos, Marco Rossi, Mai Har Sham, Carmen Silvia Passos Lima, Kexia Cai
Publikováno v:
Angiogenesis & Therapeutic Targets In Cancer
Angiogenesis plays rate limiting roles in tumor growth and invasion. Angiogenesis inhibition has been proposed as a general strategy to fight against cancers. This book covers different therapeutic targets for angiogenesis interventions with emphasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d0029877ed6b374c1d8924349c29d6d
https://doi.org/10.2174/97816080500791100101
https://doi.org/10.2174/97816080500791100101
Autor:
null Ellen Kossoff, null Wen W. Ma
Publikováno v:
Angiogenesis & Therapeutic Targets In Cancer ISBN: 9781608050079
Angiogenesis is now a proven therapeutic cancer target. Approaches targeting the vascular endothelial growth factor and receptor (VEGF/VEGFR) axis have yielded success in gastrointestinal cancers. Bevacizumab is a humanized recombinant monoclonal ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2a0066dc26477419bd2868f8b7ac1a6
https://doi.org/10.2174/978160805007911001010018
https://doi.org/10.2174/978160805007911001010018
Publikováno v:
Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine. 1(3)
OBJECTIVE: To study the anti-tumor and immunological effect of extracts from Thymus quinquecostatus Celak on mice transplanted S180 tumor cells. METHODS: Different doses of volatile oil and alcohol extracted substances from Thymus quinquecostatus Cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98a6c9e1433320cf66af0dd6b092adcf
https://pubmed.ncbi.nlm.nih.gov/15339564
https://pubmed.ncbi.nlm.nih.gov/15339564
Autor:
Shen H; Shenzhen Hospital, Southern Medical University, Xinhu Road 1333, Baoan District, Shenzhen 518110, Guangdong, China., Zhang Q; Shenzhen Hospital, Southern Medical University, Xinhu Road 1333, Baoan District, Shenzhen 518110, Guangdong, China., Li S; Shenzhen Hospital, Southern Medical University, Xinhu Road 1333, Baoan District, Shenzhen 518110, Guangdong, China., Huang T; Shenzhen Hospital, Southern Medical University, Xinhu Road 1333, Baoan District, Shenzhen 518110, Guangdong, China., Ma W; Shenzhen Hospital, Southern Medical University, Xinhu Road 1333, Baoan District, Shenzhen 518110, Guangdong, China., Wang D; Shenzhen Hospital, Southern Medical University, Xinhu Road 1333, Baoan District, Shenzhen 518110, Guangdong, China. Electronic address: 1825616903@qq.com., Li P; School of Food and Drug, Shenzhen Polytechnic University, No. 7098 Liuxian Avenue, Nanshan District, Shenzhen 518055, Guangdong, China. Electronic address: lipengwd@szpt.edu.cn.
Publikováno v:
Journal of global antimicrobial resistance [J Glob Antimicrob Resist] 2024 Nov 20. Date of Electronic Publication: 2024 Nov 20.
Autor:
Ma W; School of Foreign Languages and Literature, Shandong University, Jinan, China., Dai X; School of Foreign Languages and Literature, Shandong University, Jinan, China. 202111619@mail.sdu.edu.cn., Zhang H; School of Foreign Languages and Literature, Shandong University, Jinan, China. hao.zhang0099@sdu.edu.cn.
Publikováno v:
Journal of autism and developmental disorders [J Autism Dev Disord] 2024 Nov 18. Date of Electronic Publication: 2024 Nov 18.