Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Wen NI Chang"'
Autor:
Gang-Hui Lee, Shian-Ying Sung, Wen-Ni Chang, Tseng-Ting Kao, Hung-Chi Tu, Tsun-Hsien Hsiao, Martin K. Safo, Tzu-Fun Fu
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 10 (2023)
Externí odkaz:
https://doaj.org/article/76c698234acf4d17b79e4de551088bf5
Autor:
Wen NI Chang, 張文妮
100
The purpose of this study was to explore family support services and needs for families having developmental delay children. A total of 400 questionnaires were sent out all over Taiwan with convenient sampling and 320 returned, with the reco
The purpose of this study was to explore family support services and needs for families having developmental delay children. A total of 400 questionnaires were sent out all over Taiwan with convenient sampling and 320 returned, with the reco
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/66220126439080163729
Autor:
Gang-Hui Lee, Shian-Ying Sung, Wen-Ni Chang, Tseng-Ting Kao, Hung-Chi Du, Tsun-Hsien Hsiao, Martin K. Safo, Tzu-Fun Fu
Publikováno v:
Disease Models & Mechanisms, Vol 5, Iss 6, Pp 785-795 (2012)
SUMMARY The etiology of epilepsy is a very complicated, multifactorial process that is not completely understood. Therefore, the availability of epilepsy animal models induced by different mechanisms is crucial in advancing our knowledge and developi
Externí odkaz:
https://doaj.org/article/dc594439f5a64b5ca525c2bba5f722a2
Autor:
Tzu Fun Fu, Bing-Hung Chen, Chien-Chih Chiu, Jen Ning Tsai, Tseng Ting Kao, Wan Yu Chi, Wen Ni Chang, Wangta Liu, Shih Shin Liang
Publikováno v:
Zebrafish. 14:223-235
Dihydrofolate reductase (DHFR) reduces folic acid and recycles dihydrofolate generated during dTMP biosynthesis to tetrahydrofolate. DHFR is upregulated in rapidly proliferating cells and hence a favored target of antifolate drug against cancers, aut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce97045065cab0d43081c2a61a6f7031
https://doi.org/10.1089/zeb.2016.1381
https://doi.org/10.1089/zeb.2016.1381
Autor:
Chun-Jung Chen, Hong Hsiang Guan, Wen Ni Chang, Atsushi Nakagawa, Hoong-Kun Fun, Tseng Ting Kao, Phimonphan Chuankhayan, Chien-Chih Lin, Tzu Fun Fu
Publikováno v:
Acta Crystallographica Section D: Biological Crystallography
Structures of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase from zebrafish and its complexes are reported.
10-Formyltetrahydrofolate dehydrogenase (FDH), which is composed of a small N-terminal domain (Nt-FDH) and a large C-ter
10-Formyltetrahydrofolate dehydrogenase (FDH), which is composed of a small N-terminal domain (Nt-FDH) and a large C-ter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5d48834e82b60affaec42ee5ecca602
https://doi.org/10.1107/s1399004715002928
https://doi.org/10.1107/s1399004715002928
Autor:
Gang Hui Lee, Bing Hung Chen, Hsin Ru Wu, Wen Ni Chang, Cha Ying Lin, Tseng Ting Kao, Huai-Jen Tsai, Jen Ning Tsai, Tsun Hsien Hsiao, Yau-Hung Chen, Tzu Fun Fu
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1840:2340-2350
Background Folate is an essential nutrient for cell survival and embryogenesis. 10-Formyltetrahydrofolate dehydrogenase (FDH) is the most abundant folate enzyme in folate-mediated one-carbon metabolism. 10-Formyltetrahydrofolate dehydrogenase convert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d73d7ff57be4bad582b61ca49d8f921
https://doi.org/10.1016/j.bbagen.2014.04.009
https://doi.org/10.1016/j.bbagen.2014.04.009
Publikováno v:
Protein Expression and Purification. 72:217-222
10-Formyltetrahydrofolate dehydrogenase from zebrafish has been cloned and expressed in both Escherichia coli and yeast. In addition, the N-terminal and C-terminal domains have also been cloned and expressed. Each expressed protein was purified to ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11a747ad9494ddb1022317dbfb334549
https://doi.org/10.1016/j.pep.2010.04.003
https://doi.org/10.1016/j.pep.2010.04.003
Publikováno v:
Drug Metabolism and Disposition. 37:302-309
A cDNA encoding for zebrafish gamma-glutamyl hydrolase (gammaGH) was cloned and inserted into a pET43.1a vector via SmaI and EcoRI sites and expressed in Rosetta (DE3) cells as a Nus-His-tag fusion enzyme (NH-zgammaGH). After induction with isopropyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::923688719c459e2bb03c9cebba5c5a4a
https://doi.org/10.1124/dmd.108.024042
https://doi.org/10.1124/dmd.108.024042
Autor:
Bing Hung Chen, Wen Ni Chang, Yi Shao Chung, Tseng Ting Kao, Gang Hui Lee, Chia Jen Lin, Tzu Fun Fu, Jan Jong Hung, Tsun Hsien Hsiao
Alcoholism induces folate deficiency and increases the risk for embryonic anomalies. However, the interplay between ethanol exposure and embryonic folate status remains unclear. To investigate how ethanol exposure affects embryonic folate status and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e5a79bd678e176c5594698f0ccd0b68
https://europepmc.org/articles/PMC3911513/
https://europepmc.org/articles/PMC3911513/
Autor:
Hung Chi Du, Tseng Ting Kao, Wen Ni Chang, Gang Hui Lee, Tsun Hsien Hsiao, Shian Ying Sung, Martin K. Safo, Tzu Fun Fu
Publikováno v:
Disease Models & Mechanisms.
SummaryThe etiology of epilepsy is a very complicated, multifactorial process that is not completely understood. Therefore, the availability of epilepsy animal models induced by different mechanisms is crucial in advancing our knowledge and developin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be441a266e2f136373e9f7e33c5b4f27
https://doi.org/10.1242/dmm.009449
https://doi.org/10.1242/dmm.009449