Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Wen Liang, Pan"'
Autor:
Wing Ping Fong, Yau Sang Chan, Xiu Juan Ye, Wen Liang Pan, Jack Ho Wong, Tzi Bun Ng, Chris Zhi Yi Zhang, Evandro Fei Fang
Supplementary Figures 1-3 from Momordica Charantia Lectin, a Type II Ribosome Inactivating Protein, Exhibits Antitumor Activity toward Human Nasopharyngeal Carcinoma Cells In Vitro and In Vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21798775d184c033a21596b8d56c8514
https://doi.org/10.1158/1940-6207.22525227
https://doi.org/10.1158/1940-6207.22525227
Autor:
George C. Tsokos, Kamalpreet Nagpal, Abel Suárez-Fueyo, Nobuya Yoshida, Wen Liang Pan, Andrew P. Ferretti, Maria Tsokos
Publikováno v:
J Immunol
Protein phosphatase 2A (PP2A) composed of a scaffold subunit, a catalytic subunit, and multiple regulatory subunits is a ubiquitously expressed serine/threonine phosphatase. We have previously shown that the PP2A catalytic subunit is increased in T c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa4195b45d7046a6fcf83452963bf13e
https://europepmc.org/articles/PMC8026731/
https://europepmc.org/articles/PMC8026731/
Publikováno v:
Acta Crystallographica Section E, Vol 69, Iss 11, Pp o1642-o1642 (2013)
In the title compound, C8H9ClN2O, the dihedral angle between the benzene ring and the methylamide substituent is 68.39 (11)°. In the crystal, molecules are linked by N—H...O hydrogen bonds, forming layers parallel to the ab plane.
Externí odkaz:
https://doaj.org/article/f8197d9ea71d4f67a44d183711139541
Autor:
Amir Sharabi, Wen Liang Pan, Nobuya Yoshida, Catalina Burbano, Andrew P. Ferretti, Yinfeng Zhang, George C. Tsokos, Maria Tsokos
Publikováno v:
JCI Insight
JCI Insight, Vol 5, Iss 19 (2020)
JCI Insight, Vol 5, Iss 19 (2020)
Protein phosphatase 2A is a ubiquitously expressed serine/threonine phosphatase that comprises a scaffold, a catalytic, and multiple regulatory subunits and has been shown to be important in the expression of autoimmunity. We considered that a distin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f942cdb338df7db8dd28f30755fb0e05
http://europepmc.org/articles/PMC7566706
http://europepmc.org/articles/PMC7566706
Autor:
Hao Li, George C. Tsokos, Pui Lee, Amir Sharabi, Michihito Kono, Maria Tsokos, Esra Meidan, John P. Manis, Vasileios C. Kyttaris, José C. Crispín, Christina Ioannidis, Sokratis A. Apostolidis, Shuilian Yu, Wen Liang Pan, Noe Rodriguez Rodriguez
Publikováno v:
JCI Insight. 5
Protein phosphatase 2A (PP2A), a serine/threonine phosphatase, has been shown to control T cell function. We found that in vitro–activated B cells and B cells from various lupus-prone mice and patients with systemic lupus erythematosus display incr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0105c7949420cafcd9d6c6c3b012cca0
https://doi.org/10.1172/jci.insight.130655
https://doi.org/10.1172/jci.insight.130655
Autor:
Evandro Fei Fang, Chris Zhi Yi Zhang, Lin Zhang, Jack Ho Wong, Yau Sang Chan, Wen Liang Pan, Xiu Li Dan, Cui Ming Yin, Chi Hin Cho, Tzi Bun Ng
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e41592 (2012)
Breast cancer ranks as a common and severe neoplasia in women with increasing incidence as well as high risk of metastasis and relapse. Translational and laboratory-based clinical investigations of new/novel drugs are in progress. Medicinal plants ar
Externí odkaz:
https://doaj.org/article/53b6d43965fd479eb43d178be3eecb99
Autor:
Yan Wang, Yuan Hao, David Chi Cheong Wan, Wing Cheong Chan, Wen Liang Pan, John Wong, Tzi Bun Ng
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1864:3837-3846
Chemokine receptor CXCR4 was involved in the progression of breast cancer to a metastatic phenotype, leading to the major cause of death in patients. A more in-depth understanding of signaling mechanism underlying CXCR4 is critical to develop effecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b937dbe9bd21a8c794853baaa5bba1a5
https://doi.org/10.1016/j.bbadis.2018.09.008
https://doi.org/10.1016/j.bbadis.2018.09.008
Autor:
Nobuya Yoshida, George C. Tsokos, Nicole E Skinner, Vasileios C. Kyttaris, Wen Liang Pan, Michihito Kono, Kayaho Maeda, Maria Tsokos
Publikováno v:
Proceedings of the National Academy of Sciences. 115:9288-9293
Th17 cells favor glycolytic metabolism, and pyruvate dehydrogenase (PDH) is the key bifurcation enzyme, which in its active dephosphorylated form advances the oxidative phosphorylation from glycolytic pathway. The transcriptional factor, inducible cA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21cd5434bca493ad64aea9dad03eaec3
https://doi.org/10.1073/pnas.1805717115
https://doi.org/10.1073/pnas.1805717115
Autor:
Milena Vukelic, Wen Liang Pan, Michihito Kono, Catalina Burbano, Nobuya Yoshida, Seo Yeon K. Orite, Masataka Umeda, Maria Tsokos, George C. Tsokos, Eri Katsuyama, Irina Stocton-Gavanescu, Kayaho Maeda
Th1 and Th17 are important in the pathogenesis of autoimmune diseases and they depend on glycolysis as a source of energy. T cell antigen receptor signaling phosphorylates a serine/threonine kinase, calcium/calmodulin-dependent protein kinase IV (CaM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7857f3098065e9ab3e2d4d3ebaab00d7
https://europepmc.org/articles/PMC6629104/
https://europepmc.org/articles/PMC6629104/
Autor:
Amir Sharabi, Hao Li, Vaishali R. Moulton, Maria Tsokos, Wen Liang Pan, Isaac R. Kasper, Esra Meidan, George C. Tsokos
Publikováno v:
JCI Insight. 4
Tregs require IL-2 signaling for signal transducer and activator of transcription 5–mediated (STAT5-mediated) induction of Foxp3. Although phosphatase 2A (PP2A) is a negative regulator of IL-2 production in effector T cells and Tregs do not produce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45f92eaa4167bf7459cabede95c5b3fd
https://doi.org/10.1172/jci.insight.126294
https://doi.org/10.1172/jci.insight.126294