Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Wen Jye Lin"'
Autor:
Hsiao-Han Lin, Cheng-Wei Chang, Yu-Ting Liao, Shauh-Der Yeh, Hsiu-Ping Lin, Hui-Min Ho, Chantal Hoi-Yin Cheung, Hsueh-Fen Juan, Yi-Rong Chen, Yu-Wen Su, Li-Mei Chen, Tse-Hua Tan, Wen-Jye Lin
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract DUSP22, an atypical dual-specificity phosphatase enzyme, plays a significant role in regulating multiple kinase signaling pathways by dephosphorylation. Our study demonstrated that decreased DUSP22 expression is associated with shorter disea
Externí odkaz:
https://doaj.org/article/9070ec439dfa49ff8d34cbdafe135424
Autor:
Pei-Ju Tsai, Ming-Yu Chen, Wei-Chan Hsu, Su-Fang Lin, Po-Chiang Chan, Hsin-Hsin Chen, Cheng-Yuan Kao, Wen-Jye Lin, Tsung-Hsien Chuang, Guann-Yi Yu, Yu-Wen Su
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110388- (2024)
Summary: Phosphatase and tensin homolog (PTEN) is vital for B cell development, acting as a key negative regulator in the PI3K signaling pathway. We used CD23-cre to generate PTEN-conditional knockout mice (CD23-cKO) to examine the impact of PTEN mut
Externí odkaz:
https://doaj.org/article/d812a20ceb854dd786b6517a2a8e0ad6
Autor:
Cherng-Shyang Chang, Wen-Hsuan Yu, Chang-Chao Su, Jhen-Wei Ruan, Chiao-Mei Lin, Chih-Ting Huang, Yi-Ting Tsai, I-Jung Lin, Chao-Yang Lai, Tsung-Hsien Chuang, Wen-Jye Lin, Tse-Hua Tan, Hsuan-Cheng Huang, Hsueh-Fen Juan, Cheng-Yuan Kao
Publikováno v:
iScience, Vol 25, Iss 2, Pp 103738- (2022)
Summary: Single-cell RNA sequencing (scRNA-seq) approach can broadly and specifically evaluate the individual cells with minimum detection bias. To explore the individual compositional and transcriptional alteration of intestinal leukocytes in the Du
Externí odkaz:
https://doaj.org/article/4f65673e087a4d40bdb5e3d0a441551a
Autor:
Hiroshi Kano, Kouji Izumi, Kaoru Hiratsuka, Ren Toriumi, Ryunosuke Nakagawa, Shuhei Aoyama, Taiki Kamijima, Takafumi Shimada, Renato Naito, Suguru Kadomoto, Hiroaki Iwamoto, Hiroshi Yaegashi, Shohei Kawaguchi, Takahiro Nohara, Kazuyoshi Shigehara, Yoshifumi Kadono, Yohei Saito, Kyoko Nakagawa‐Goto, Kazuaki Yoshioka, Hiroki Nakata, Wen‐Jye Lin, Atsushi Mizokami
Publikováno v:
Cancer Science. 114:1479-1490
The suppression of androgen receptor (AR) expression exacerbates the migration potential of prostate cancer. This study identified a previously unrecognized regulation of the AR-controlled pathway that promotes migration potential in prostate cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d8cae83249b5cb1d4688a12d418ed84
https://doi.org/10.1111/cas.15683
https://doi.org/10.1111/cas.15683
Autor:
Wen-Ling Kuo, Lin-Lu Tseng, Che-Chang Chang, Chih-Jung Chen, Mei-Ling Cheng, Hsin-Hung Cheng, Meng-Jen Wu, Yu-Lun Chen, Ruei-Ting Chang, Hsiang-Yu Tang, Yong-Chen Hsu, Wen-Jye Lin, Cheng-Yuan Kao, Wen-Ping Hsieh, Hsing-Jien Kung, Wen-Ching Wang
Publikováno v:
Diagnostics, Vol 11, Iss 8, p 1460 (2021)
Predictive metabolic biomarkers for the recurrent luminal breast cancer (BC) with hormone receptor (HR)-positive and human epidermal growth factor receptor type 2 (HER2)-negative are lacking. High levels of O-GlcNAcylation (O-GlcNAc) and pyruvate kin
Externí odkaz:
https://doaj.org/article/6fd67ce731a940518ea085135d1a71b6
Autor:
Chawnshang Chang, Wen-Jye Lin, Hiroshi Miyamoto, Lei Li, Liang Liang, Kuo-Pao Lai, Kouji Izumi, Lei-Ya Fang
PDF file, 1659K, S1. Effects of THP-1 on cell migration, acinar morphogenesis, and downstream signaling in BPH-1 cells. S2. H&E staining of the anterior prostate from athymic nude mice 60 days after orthoptoic injection of either THP-1 or RWPE-1 cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d79bf758bd0c0c0b0ec008439233398e
https://doi.org/10.1158/0008-5472.22398218.v1
https://doi.org/10.1158/0008-5472.22398218.v1
Autor:
Chawnshang Chang, Wen-Jye Lin, Hiroshi Miyamoto, Lei Li, Liang Liang, Kuo-Pao Lai, Kouji Izumi, Lei-Ya Fang
PDF file, 65K, Table S1. CCL4 expression in prostate tissue microarrays. Table S2. CCL4 expression in prostatic adenocarcinoma and pathologic profile.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95dbf7cba3e327bfd6b855d3508eee55
https://doi.org/10.1158/0008-5472.22398212
https://doi.org/10.1158/0008-5472.22398212
Autor:
Pei-Ju Tsai, Wei-Chan Hsu, Ming-Yu Chen, Po-Chiang Chan, Cheng-Yuan Kao, Wen-Jye Lin, Tsung-Hsien Chuang, Su-Fang Lin, Guann-Yi Yu, Yu-Wen Su
Phosphatase and tensin homolog (PTEN) is a negative regulator for PI3K signaling essential for B cell development. To explore the physiological effects of PTEN mutation on peripheral B cells, we generated CD23/cre-PTENFlox/Flox (CD23-cKO) mice in thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d009b72baad1cca61d4c28b06a94752
https://doi.org/10.21203/rs.3.rs-2616509/v1
https://doi.org/10.21203/rs.3.rs-2616509/v1
Autor:
Te-Haw Wu, Shu-Yi Lin, Lu-Chen Yeh, Wen-Jye Lin, Chun-Nien Yao, Shu-Ping Chen, Fang-Hsuean Liao
Publikováno v:
ACS Applied Bio Materials. 4:6527-6538
A major challenge in the use of chemotherapy and immunotherapy is hypoxia-induced progression of tumor cells. We aim to curb hypoxia using metal-based O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f6e82a17f593329e3c70386811180d9
https://doi.org/10.1021/acsabm.1c00667
https://doi.org/10.1021/acsabm.1c00667