Zobrazeno 1 - 10
of 319
pro vyhledávání: '"Wen Jen Hwu"'
Autor:
Akash Mitra, Miles C. Andrews, Whijae Roh, Marianna Petaccia De Macedo, Courtney W. Hudgens, Fernando Carapeto, Shailbala Singh, Alexandre Reuben, Feng Wang, Xizeng Mao, Xingzhi Song, Khalida Wani, Samantha Tippen, Kwok-Shing Ng, Aislyn Schalck, Donald A. Sakellariou-Thompson, Eveline Chen, Sangeetha M. Reddy, Christine N. Spencer, Diana Wiesnoski, Latasha D. Little, Curtis Gumbs, Zachary A. Cooper, Elizabeth M. Burton, Patrick Hwu, Michael A. Davies, Jianhua Zhang, Chantale Bernatchez, Nicholas Navin, Padmanee Sharma, James P. Allison, Jennifer A. Wargo, Cassian Yee, Michael T. Tetzlaff, Wen-Jen Hwu, Alexander J. Lazar, P. Andrew Futreal
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Immunotherapies now dominate the treatment landscape for melanoma, but why they only work in a subset of patients remains unclear. Here, the authors perform an immunogenomic analysis on 67 intratumor sub-regions of a PD-1 inhibitor resistant melanoma
Externí odkaz:
https://doaj.org/article/97e9b4c4c8f048e9a752f694b5bd17ef
Autor:
Jennifer L. McQuade, Jade Homsi, Carlos A. Torres-Cabala, Roland Bassett, Rashmi Murthy Popuri, Marihella L. James, Luis M. Vence, Wen-Jen Hwu
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-9 (2018)
Abstract Background HDIL-2 is approved for advanced melanoma based on its durable antitumor activity. MAGE-A3 cancer immunotherapeutic (MAGE-A3 CI) is a recombinant MAGE-A3 protein combined with an immunostimulant adjuvant system and has shown antitu
Externí odkaz:
https://doaj.org/article/a2e99d3cbedd4f4e820bcd11f4488ad1
Autor:
Daniel H Johnson, Chrystia M Zobniw, Van A Trinh, Junsheng Ma, Roland L Bassett, Noha Abdel-Wahab, Jaime Anderson, Jennifer E Davis, Jocelyn Joseph, Marc Uemura, Ali Noman, Hamzah Abu-Sbeih, Cassian Yee, Rodabe Amaria, Sapna Patel, Hussein Tawbi, Isabella C Glitza, Michael A Davies, Michael K Wong, Scott Woodman, Wen-Jen Hwu, Patrick Hwu, Yinghong Wang, Adi Diab
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-8 (2018)
Abstract Background Immune-related enterocolitis (irEC) is the most common serious complication from checkpoint inhibitors (CPIs). The current front-line treatment for irEC, high-dose corticosteroids (CS), have significant side effects and prolonged
Externí odkaz:
https://doaj.org/article/1943075ceb3442f28ca3f0d6fae4550c
Autor:
Jennifer A. Wargo, Lynda Chin, James P. Allison, Padmanee Sharma, Jorge Blando, P. Andrew Futreal, Jianhua Hu, Arlene H. Sharpe, Willem W. Overwijk, Wencai Ma, R. Eric Davis, Victor Prieto, Lawrence N. Kwong, Rodabe N. Amaria, Ignacio I. Wistuba, Luis M. Vence, Scott E. Woodman, Isabella C. Glitza, Adi Diab, Wen-Jen Hwu, Patrick Hwu, Sapna P. Patel, Alexander J. Lazar, Lauren Haydu, Jeffrey E. Gershenwald, Michael A. Davies, Russell J. Broaddus, Michael T. Tetzlaff, Wei-Shen Chen, Sangeetha M. Reddy, Qing Chang, Hong Jiang, Jacob L. Austin-Breneman, Mariana Petaccia De Macedo, Khalida Wani, Vancheswaran Gopalakrishnan, Roland L. Bassett, John P. Miller, Peter A. Prieto, Christine N. Spencer, Zachary A. Cooper, Alexandre Reuben, Whijae Roh, Pei-Ling Chen
Supplementary Figure 1. Immune profiling of pre-treatment, on-treatment and progression CTLA-4 blockade samples by immunohistochemistry. Supplementary Figure 2. Myeloid cell profiling of pre-treatment, on-treatment and progression CTLA-4 blockade sam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a94b76b26635b304089e2c2105c2324
https://doi.org/10.1158/2159-8290.22531185.v1
https://doi.org/10.1158/2159-8290.22531185.v1
Autor:
Jennifer A. Wargo, Lynda Chin, James P. Allison, Padmanee Sharma, Jorge Blando, P. Andrew Futreal, Jianhua Hu, Arlene H. Sharpe, Willem W. Overwijk, Wencai Ma, R. Eric Davis, Victor Prieto, Lawrence N. Kwong, Rodabe N. Amaria, Ignacio I. Wistuba, Luis M. Vence, Scott E. Woodman, Isabella C. Glitza, Adi Diab, Wen-Jen Hwu, Patrick Hwu, Sapna P. Patel, Alexander J. Lazar, Lauren Haydu, Jeffrey E. Gershenwald, Michael A. Davies, Russell J. Broaddus, Michael T. Tetzlaff, Wei-Shen Chen, Sangeetha M. Reddy, Qing Chang, Hong Jiang, Jacob L. Austin-Breneman, Mariana Petaccia De Macedo, Khalida Wani, Vancheswaran Gopalakrishnan, Roland L. Bassett, John P. Miller, Peter A. Prieto, Christine N. Spencer, Zachary A. Cooper, Alexandre Reuben, Whijae Roh, Pei-Ling Chen
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d3386a59c8445bd1739152486738ced
https://doi.org/10.1158/2159-8290.22531188
https://doi.org/10.1158/2159-8290.22531188
Autor:
Jennifer A. Wargo, Lynda Chin, James P. Allison, Padmanee Sharma, Jorge Blando, P. Andrew Futreal, Jianhua Hu, Arlene H. Sharpe, Willem W. Overwijk, Wencai Ma, R. Eric Davis, Victor Prieto, Lawrence N. Kwong, Rodabe N. Amaria, Ignacio I. Wistuba, Luis M. Vence, Scott E. Woodman, Isabella C. Glitza, Adi Diab, Wen-Jen Hwu, Patrick Hwu, Sapna P. Patel, Alexander J. Lazar, Lauren Haydu, Jeffrey E. Gershenwald, Michael A. Davies, Russell J. Broaddus, Michael T. Tetzlaff, Wei-Shen Chen, Sangeetha M. Reddy, Qing Chang, Hong Jiang, Jacob L. Austin-Breneman, Mariana Petaccia De Macedo, Khalida Wani, Vancheswaran Gopalakrishnan, Roland L. Bassett, John P. Miller, Peter A. Prieto, Christine N. Spencer, Zachary A. Cooper, Alexandre Reuben, Whijae Roh, Pei-Ling Chen
Supplementary Table S1a. Patient Cohort Clinical Summary. Supplementary Table S1b. Patient clinical characteristics. Supplementary Table S1c. Immune profiling by IHC sample log. Supplementary Table S1d. Nanostring 54 sample log. Supplementary Table S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a24f9934ab5d9d54efae31d3ca23659f
https://doi.org/10.1158/2159-8290.22531182
https://doi.org/10.1158/2159-8290.22531182
Autor:
Patrick Hwu, Audrey Gonzalez, Seth Wardell, Renjith Ramachandran, Christopher Toth, Orenthial J. Fulbright, Rahmatu Mansaray, Michael A. Davies, Janice N. Cormier, Richard Royal, Anthony Lucci, Jeffrey E. Gershenwald, Jeffrey E. Lee, Merrick I. Ross, Sapna Patel, Wen-Jen Hwu, Agop Bedikian, Jade Homsi, Kevin Kim, Nicholas Papadopoulos, Victor Prieto, Elizabeth Shpall, John D. McMannis, Valen E. Johnson, Michelle Glass, Gladys Alvarado, Sandy Mahoney, Gregory Lizee, Richard Wu, Jessica Chacon, Priscilla Miller, Patricia S. Fox, Minying Zhang, Chantale Bernatchez, Laszlo G. Radvanyi
PDF file - 115K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23947fc80f4534d59ef0e49b90e97e01
https://doi.org/10.1158/1078-0432.22452185
https://doi.org/10.1158/1078-0432.22452185
Autor:
Antoni Ribas, Toni K. Choueiri, Rodolfo F. Perini, Blanca Homet Moreno, Xinxin Shu, Seth Robey, Lokesh Jain, Marihella James, Shailender Bhatia, Deborah J. Wong, Nancy A. Dawson, Donald P. Lawrence, Wen-Jen Hwu, David F. McDermott, John A. Thompson, F. Stephen Hodi, Michael B. Atkins
Purpose: Pembrolizumab monotherapy, ipilimumab monotherapy, and pegylated interferon alfa-2b (PEG-IFN) monotherapy are active against melanoma and renal cell carcinoma (RCC). We explored the safety and preliminary antitumor activity of pembrolizumab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a51e52add57777cc2d463d414a0e017
https://doi.org/10.1158/1078-0432.c.6527397.v1
https://doi.org/10.1158/1078-0432.c.6527397.v1
Autor:
Kevin B. Kim, Patrick Hwu, Roland L. Bassett, John J. Wright, Janet E. Dancey, Wenbin Liu, Sanjay Gupta, Chaan S. Ng, Wanleng Deng, Sha Huang, Quanyun Xu, Timothy L. Madden, Kirk S. Culotta, Victor G. Prieto, Alexander J. Lazar, Wen-Jen Hwu, Agop Y. Bedikian, Nicholas E. Papadopoulos, Patricia S. Fox, Michael A. Davies
PDF file - 70K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cf17aa3a0b0bf0a44c2b84511a50bd7
https://doi.org/10.1158/1078-0432.22444277.v1
https://doi.org/10.1158/1078-0432.22444277.v1
Autor:
Tara C. Gangadhar, Keaven M. Anderson, Scot Ebbinghaus, S. Peter Kang, Jin Zhang, Andrea Perrone, Dinesh P. de Alwis, Amita Patnaik, Jeffrey S. Weber, Peter Hersey, Roxana Dronca, Adil Daud, Caroline Robert, Omid Hamid, F. Stephen Hodi, Antoni Ribas, Anthony M. Joshua, Jedd D. Wolchok, Wen-Jen Hwu, Richard Kefford, Jeroen Elassaiss-Schaap, Richard W. Joseph
Supplemental Table
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26176e6e3787608edb4bcad0a45a1799
https://doi.org/10.1158/1078-0432.22468532.v1
https://doi.org/10.1158/1078-0432.22468532.v1