Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Wen Hui Tsien"'
Autor:
M. Griffin, Jarema Peter Kochan, M. Nettleton, Wen-Hui Tsien, Michael Mallamaci, Richard Anthony Chizzonite, John Hakimi
Publikováno v:
Journal of Biological Chemistry. 268:22076-22083
The high affinity IgE Fc receptor (Fc epsilon RI), found on mast cells and basophils, is a tetrameric receptor complex. The extracellular portion of the Fc epsilon RI alpha subunit consists of two immunoglobulin-like domains and binds IgE in the abse
Autor:
Herbert Sheppard, Wen Hui Tsien
Publikováno v:
Life Sciences. 16:139-148
The effect of pH on the extent of binding of cyclic AMP was evaluated by membrane filtration, charcoal exclusion and Sephadex G-25 chromatography. The amount of binding activity found in hemolysates of rat erythrocytes and 105,000 × g supernatants o
Autor:
Diane A. Skaleris, Phyllis Liu Osheroff, Cary M. Seals, Maurice K. Gately, John Hakimi, Wen-Hui Tsien, Darien E. Wilson
Publikováno v:
Hybridoma. 7:417-427
We describe the generation of a monoclonal anti-idiotypic (anti-id) antibody directed against affinity purified rabbit antibodies (id) to recombinant human IL-2. This monoclonal antibody, 6A12, has the ability to inhibit the neutralization of IL-2 ac
Publikováno v:
Immunopharmacology. 2:221-231
During a period of prelabeling of mouse thymus cells with any nucleoside at 4 degrees C, nucleoside phosphates accumulated, but no nucleic acid synthesis occurred. Elevating the temperature to 37 degrees C then led to incorporation into the respectiv
Autor:
Herbert Sheppard, Wen Hui Tsien
Publikováno v:
Experimental Biology and Medicine. 90:437-440
Summary1. Liver slices of rat, mouse, dog, guinea pig, rabbit and pigeon were incubated with reserpine-C14. 2. Demethylation of the 4-methoxy position of trimethoxyben-zoic acid moiety of reserpine was observed to occur, with rat liver slices most ac
Publikováno v:
Biochemical and Biophysical Research Communications. 15:546-550
Publikováno v:
Biochemical Pharmacology. 14:41-46
The administration of methandrostenolone to both castrated and control immature male rats for seven days resulted in dose-dependent increases in the RNA, DNA, and protein of the levator ani, ventral prostate, and seminal vesicles. The effect of this
Publikováno v:
Immunopharmacology. 3(3)
The ability of certain lipopolysaccharide (LPS) preparations to elevate cyclic adenosine monophosphate (cAMP) in mouse thymus cells in the presence of Ro 20–1724, 4-(3-butoxyl 4-methoxybenzyl)-2-imidazolididnone, was not related to the source of su
Publikováno v:
Immunopharmacology. 2(2)
The 15-min incorporation of 3H-thymidine (Tdr) and 3H-uridine (Ur) into nucleic acids of freshly isolated mouse thymocytes decreased steadily with time of preincubation at 37 degrees C. Sodium ascorbate at 5 mM prevented the decline of 3H-Tdr incorpo
Autor:
Wen Hui Tsien, Herbert Sheppard
Publikováno v:
Biochimica et biophysica acta. 341(2)
Slow, in contrast to rapid, freezing of a rat erythrocyte hemolysate irreversibly activated the cyclic AMP phosphodiesterase (3′:5′-cyclic-AMP 5′-nucleotidohydrolase, EC 3.1.4.17) and reduced its sensitivity to the inhibitor, BMI ( d,l -4-(3-bu