Zobrazeno 1 - 10
of 11 293
pro vyhledávání: '"Wen HUANG"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Diabetic nephropathy (DN) is a prototypical chronic energy metabolism imbalance disease. The AMPK/Sirt1/PGC-1α signaling pathway plays a pivotal role in regulating energy metabolism throughout the body. Gut microbiota ferment indigestible c
Externí odkaz:
https://doaj.org/article/bfec2f54490e4a209d953caaf01f8a52
Autor:
Guangxu Li, Yuanjiang Huang, Wenbo Han, Liyi Wei, Hongjing Huang, Yingbao Zhu, Qiao Xiao, Zujia Wang, Wen Huang, Ranhui Duan
Publikováno v:
Cell Death and Disease, Vol 15, Iss 7, Pp 1-13 (2024)
Abstract UFMylation is a highly conserved ubiquitin-like post-translational modification that catalyzes the covalent linkage of UFM1 to its target proteins. This modification plays a critical role in the maintenance of endoplasmic reticulum proteosta
Externí odkaz:
https://doaj.org/article/b21f9406ffeb47c3a48196e31193bb66
Autor:
Hang Xiang, Rongkui Luo, Yunzhi Wang, Bing Yang, Sha Xu, Wen Huang, Shaoshuai Tang, Rundong Fang, Lingli Chen, Na Zhu, Zixiang Yu, Sujie Akesu, Chuanyuan Wei, Chen Xu, Yuhong Zhou, Jianying Gu, Jianyuan Zhao, Yingyong Hou, Chen Ding
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-35 (2024)
Abstract Melanoma is one of the most prevalent skin cancers, with high metastatic rates and poor prognosis. Understanding its molecular pathogenesis is crucial for improving its diagnosis and treatment. Integrated analysis of multi-omics data from 20
Externí odkaz:
https://doaj.org/article/4f4a78f6fcdc4f14b125f8102d0245f6
Autor:
Guang-Yu Ding, Wei-Min Tan, You-Pei Lin, Yu Ling, Wen Huang, Shu Zhang, Jie-Yi Shi, Rong-Kui Luo, Yuan Ji, Xiao-Ying Wang, Jian Zhou, Jia Fan, Mu-Yan Cai, Bo Yan, Qiang Gao
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background The advances in deep learning-based pathological image analysis have invoked tremendous insights into cancer prognostication. Still, lack of interpretability remains a significant barrier to clinical application. Methods We establ
Externí odkaz:
https://doaj.org/article/87c9a85be43548f8b4e6ba684603012f
Autor:
Jianping Quan, Ming Yang, Xingwang Wang, Gengyuan Cai, Rongrong Ding, Zhanwei Zhuang, Shenping Zhou, Suxu Tan, Donglin Ruan, Jiajin Wu, Enqin Zheng, Zebin Zhang, Langqing Liu, Fanming Meng, Jie Wu, Cineng Xu, Yibin Qiu, Shiyuan Wang, Meng Lin, Shaoyun Li, Yong Ye, Fuchen Zhou, Danyang Lin, Xuehua Li, Shaoxiong Deng, Yuling Zhang, Zekai Yao, Xin Gao, Yingshan Yang, Yiyi Liu, Yuexin Zhan, Zhihong Liu, Jiaming Zhang, Fucai Ma, Jifei Yang, Qiaoer Chen, Jisheng Yang, Jian Ye, Linsong Dong, Ting Gu, Sixiu Huang, Zheng Xu, Zicong Li, Jie Yang, Wen Huang, Zhenfang Wu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Hybrid mapping is a powerful approach to efficiently identify and characterize genes regulated through mechanisms in cis. In this study, using reciprocal crosses of the phenotypically divergent Duroc and Lulai pig breeds, we perform a compre
Externí odkaz:
https://doaj.org/article/90f889317bfe466e807967daa4a618ad
Autor:
Junxiong Guo, Shuyi Gu, Lin Lin, Yu Liu, Ji Cai, Hongyi Cai, Yu Tian, Yuelin Zhang, Qinghua Zhang, Ze Liu, Yafei Zhang, Xiaosheng Zhang, Yuan Lin, Wen Huang, Lin Gu, Jinxing Zhang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract Multichannel meta-imaging, inspired by the parallel-processing capability of neuromorphic computing, offers considerable advancements in resolution enhancement and edge discrimination in imaging systems, extending even into the mid- to far-i
Externí odkaz:
https://doaj.org/article/910a92d0d9024dcd903036e9c61461aa
Autor:
Ben Pei, Yongsen Zhou, Yu Yang, Jiaxiang Ma, Rangli Cao, Wen Huang, Liliang Ouyang, Shengli Mi, Zhuo Xiong
Publikováno v:
Small Science, Vol 4, Iss 11, Pp n/a-n/a (2024)
DNA has emerged as a promising storage medium to meet the soaring need for archival data storage because of its exceptional storage density and stability. However, current DNA‐based data storage systems are incompetent of achieving high‐quality r
Externí odkaz:
https://doaj.org/article/9da311b255e443d58fe83da0089ef4e7
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 283, Iss , Pp 116929- (2024)
During pregnancy, the maternal body undergoes a series of adaptative physiological changes, leading to a slight increase in serum bile acid (BA) levels. Although the fetal liver can synthesize BAs since the first trimester through the alternative pat
Externí odkaz:
https://doaj.org/article/d268a612003e494c9026718331f93716
Autor:
Xiaoying Chen, Peijia Li, Dongqiang Hou, Min Li, Bing Chen, Kai Peng, Wen Huang, Junming Cao, Hongxia Zhao
Publikováno v:
Aquaculture Reports, Vol 36, Iss , Pp 102090- (2024)
The intestinal tract plays an important role in digestion and absorption, nutrient metabolism, and immune anti-stress. At the same time, the intestine is also the major site for pathogens and various harmful substances to invade. Probiotics, as livin
Externí odkaz:
https://doaj.org/article/c61870764be24df5b95172393bc1d68c
Autor:
Yang Zhu, Xuegang Niu, Chengyu Ding, Yuanxiang Lin, Wenhua Fang, Lingjun Yan, Junjie Cheng, Jianhua Zou, Yu Tian, Wei Huang, Wen Huang, Yuanbo Pan, Tiantian Wu, Xiaoyuan Chen, Dezhi Kang
Publikováno v:
Advanced Science, Vol 11, Iss 23, Pp n/a-n/a (2024)
Abstract Cuproptosis is a newly discovered form of programmed cell death significantly depending on the transport efficacy of copper (Cu) ionophores. However, existing Cu ionophores, primarily small molecules with a short blood half‐life, face chal
Externí odkaz:
https://doaj.org/article/6c4e3b9a5c0b4a3da8b3e9844e301301