Zobrazeno 1 - 10
of 19 495
pro vyhledávání: '"Wen CHENG"'
Publikováno v:
ACS Omega, Vol 9, Iss 42, Pp 43175-43183 (2024)
Externí odkaz:
https://doaj.org/article/4c21e94d8e20454db9fab5c350c1a397
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Glycolytic metabolic reprogramming in cancer is regulated by both cancer intrinsic variations like isocitrate dehydrogenase 1 (IDH1) status and non-cancerous microenvironment components like tumor associated macrophages (TAMs). However, the
Externí odkaz:
https://doaj.org/article/d03ed0005c334ddf9e8a2fc65d4f9a4a
Autor:
Hongkai Yao, Weifang Tong, Yunping Song, Ruoyu Li, Xuerui Xiang, Wen Cheng, Yunjiao Zhou, Yijing He, Yi Yang, Yunxi Liu, Siguang Li, Lingjing Jin
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-19 (2024)
Abstract The primary pathological change in Parkinson’s disease (PD) is the progressive degeneration of dopaminergic neurons in the substantia nigra. Additionally, excessive microglial activation and synaptic loss are also typical features observed
Externí odkaz:
https://doaj.org/article/3d44f0e51fd843db87f90dda4d717ec5
Autor:
HUANG Ye-qun, ZHOU Han-lin, TONG Xiu-ping, JI Wei-ming, SUN Yi-lan, RAO Jian-qing, WEN Cheng-rong, PANG Jie
Publikováno v:
Liang you shipin ke-ji, Vol 32, Iss 5, Pp 142-150 (2024)
As a subfield of artificial intelligence, machine learning has gained widespread application due to its exceptional ability to learn models and summarize experiences from large datasets. To address the issues of time consumption, labor intensity, poo
Externí odkaz:
https://doaj.org/article/4f7546296b394dbda04c6dfdd1628479
Autor:
Muhammad Ameen Jamal, Yixiao Cheng, Deling Jiao, Wen Cheng, Di Zou, Xia Wang, Taiyun Wei, Jianxiong Guo, Kaixiang Xu, Heng Zhao, Shaoxia Pu, Chang Yang, Yubo Qing, Baoyu Jia, Honghui Li, Rusong Zhao, Hong-Ye Zhao, Hong-Jiang Wei
Publikováno v:
Biological Research, Vol 57, Iss 1, Pp 1-18 (2024)
Abstract Background Infertility is a growing global health concern affecting millions of couples worldwide. Among several factors, an extreme body weight adversely affects reproductive functions. Leptin is a well-known adipokine that serves as an end
Externí odkaz:
https://doaj.org/article/568d092957b34cca8761e6cc29427490
Publikováno v:
Nanoenergy Advances, Vol 4, Iss 3, Pp 235-257 (2024)
The rise of the Internet of things has catalyzed extensive research in the realm of flexible wearable sensors. In comparison with conventional sensor power supply methods that are reliant on external sources, self-powered sensors offer notable advant
Externí odkaz:
https://doaj.org/article/b68b1188442e4436adf613e74383f236
Autor:
Xinxing Li, Tao Liu, Antonella Bacchiocchi, Mengxing Li, Wen Cheng, Tobias Wittkop, Fernando L Mendez, Yingyu Wang, Paul Tang, Qianqian Yao, Marcus W Bosenberg, Mario Sznol, Qin Yan, Malek Faham, Li Weng, Ruth Halaban, Hai Jin, Zhiqian Hu
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 9, Pp 2188-2209 (2024)
Abstract While whole genome sequencing (WGS) of cell-free DNA (cfDNA) holds enormous promise for detection of molecular residual disease (MRD), its performance is limited by WGS error rate. Here we introduce AccuScan, an efficient cfDNA WGS technolog
Externí odkaz:
https://doaj.org/article/61e8893361234a0aaada760b5863e691
Autor:
Yichi Chen, Xudong Li, Haitao Shang, Yucao Sun, Chunyue Wang, Xiaodong Wang, Huimin Tian, Huajing Yang, Lei Zhang, Liwen Deng, Kuikun Yang, Bolin Wu, Wen Cheng
Publikováno v:
Nano Convergence, Vol 11, Iss 1, Pp 1-15 (2024)
Abstract The immunosuppressive tumor microenvironment (TME) has become a major challenge in cancer immunotherapy, with abundant tumor-associated macrophages (TAMs) playing a key role in promoting tumor immune escape by displaying an immunosuppressive
Externí odkaz:
https://doaj.org/article/9f9cf23bd77043a3a68beb753ba30f27
Autor:
Min Wu, Tingting Wang, Nan Ji, Ting Lu, Ran Yuan, Lingxiang Wu, Junxia Zhang, Mengyuan Li, Penghui Cao, Jiarui Zhao, Guanzhang Li, Jianyu Li, Yu Li, Yujie Tang, Zhengliang Gao, Xiuxing Wang, Wen Cheng, Ming Ge, Gang Cui, Rui Li, Anhua Wu, Yongping You, Wei Zhang, Qianghu Wang, Jian Chen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Glioblastoma (GBM) is the most common brain tumor and remains incurable. Primary GBM cultures are widely used tools for drug screening, but there is a lack of genomic and pharmacological characterization for these primary GBM cultures. Here,
Externí odkaz:
https://doaj.org/article/7bb838305ea74eeda6edfce6d4224acf
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-18 (2024)
Abstract Background Prolonged interferon-γ signaling activation induces cancer resistance to therapeutics, especially immunotherapy. However, the detailed mechanisms are not well characterized. In present study, we explored cancer intrinsic resistan
Externí odkaz:
https://doaj.org/article/c1834f8a7532467794c7893b22cbe432