Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Wen, Chih ‐ Cheng"'
Autor:
Muthukumar Gunasekaran, Rachana Mishra, Progyaparamita Saha, David Morales, Wen-Chih Cheng, Arun R. Jayaraman, Jessica R. Hoffman, Lauran Davidson, Ling Chen, Aakash M. Shah, Gregory Bittle, Xuebin Fu, Antariksh Tulshyan, Mohamed Abdullah, Tami Kingsbury, Curt Civin, Peixin Yang, Michael E. Davis, Roberto Bolli, Joshua M. Hare, Sudhish Sharma, Sunjay Kaushal
Publikováno v:
iScience, Vol 25, Iss 8, Pp 104656- (2022)
Summary: Successful cell therapy requires cells to resist the hostile ischemic myocardium, be retained to continue secreting cardioprotective growth factors/exosomes, and resist immunological host responses. Clinically relevant stem/progenitor cells
Externí odkaz:
https://doaj.org/article/cfa3170dcc4846bba20f01a55e64e98d
Autor:
Wen-Chih Cheng, Troy Horn, Maya Zayats, Georges Rizk, Samuel Major, Hongying Zhu, Joseph Russell, Zhiguang Xu, Richard E. Rothman, Alfredo Celedon
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Culture-based diagnostic methods for microorganism detection are time-consuming but still the gold standard for conditions such as sepsis. Here the authors present an amplification and purification-free method to detect microorganisms in bodily fluid
Externí odkaz:
https://doaj.org/article/44f130550ba44ae8a92f53c241c2313e
Autor:
Sheng-Yao Su, I-Hsuan Lu, Wen-Chih Cheng, Wei-Chun Chung, Pao-Yang Chen, Jan-Ming Ho, Shu-Hwa Chen, Chung-Yen Lin
Publikováno v:
BMC Genomics, Vol 21, Iss S3, Pp 1-8 (2020)
Abstract Background DNA methylation is a crucial epigenomic mechanism in various biological processes. Using whole-genome bisulfite sequencing (WGBS) technology, methylated cytosine sites can be revealed at the single nucleotide level. However, the W
Externí odkaz:
https://doaj.org/article/d017dfdcbaa84730a186f588ce3dc0bf
Autor:
Tzu-Tang Lin, Li-Yen Yang, I-Hsuan Lu, Wen-Chih Cheng, Zhe-Ren Hsu, Shu-Hwa Chen, Chung-Yen Lin
Publikováno v:
mSystems, Vol 6, Iss 6 (2021)
ABSTRACT Antimicrobial peptides (AMPs) are innate immune components that have recently stimulated considerable interest among drug developers due to their potential as antibiotic substitutes. AMPs are notable for their fundamental properties of micro
Externí odkaz:
https://doaj.org/article/016a829d7c734f2aaa945dc254f7824d
Publikováno v:
Pharmaceuticals, Vol 15, Iss 4, p 422 (2022)
Anticancer peptides (ACPs) are selective and toxic to cancer cells as new anticancer drugs. Identifying new ACPs is time-consuming and expensive to evaluate all candidates’ anticancer abilities. To reduce the cost of ACP drug development, we collec
Externí odkaz:
https://doaj.org/article/68648c10ca034501a63d44297d403b7a
Autor:
Xianghui Chen, Guiqin Wang, Yu Zhang, Margaret Dayhoff-Brannigan, Nicola L Diny, Mingjun Zhao, Ge He, Cierra N Sing, Kyle A Metz, Zachary D Stolp, Abdel Aouacheria, Wen-Chih Cheng, J Marie Hardwick, Xinchen Teng
Publikováno v:
PLoS Genetics, Vol 14, Iss 8, p e1007592 (2018)
Yeast WHI2 was originally identified in a genetic screen for regulators of cell cycle arrest and later suggested to function in general stress responses. However, the function of Whi2 is unknown. Whi2 has predicted structure and sequence similarity t
Externí odkaz:
https://doaj.org/article/6da71e8946194a80a1079b79bc8b4a3e
Autor:
Martin S. Taylor, Connie Wu, Peter C. Fridy, Stephanie J. Zhang, Yasmeen Senussi, Justina C. Wolters, Wen-Chih Cheng, John Heaps, Bryant D. Miller, Kei Mori, Limor Cohen, Hua Jiang, Kelly R. Molloy, Brian T. Chait, Michael Goggins, Irun Bhan, Joseph W. Franses, Xiaoyu Yang, Mary-Ellen Taplin, Xinan Wang, David C. Christiani, Bruce E. Johnson, Matthew Meyerson, Ravindra Uppaluri, Ann Marie Egloff, Elyssa N. Denault, Laura M. Spring, Tian-Li Wang, Ie-Ming Shih, Euihye Jung, Kshitij S. Arora, Lawrence R. Zukerberg, Osman H. Yilmaz, Gary Chi, Bryanna L. Norden, Yuhui Song, Linda Nieman, Aparna R. Parikh, Matthew Strickland, Ryan B. Corcoran, Tomas Mustelin, George Eng, Ömer H. Yilmaz, Ursula A. Matulonis, Steven J. Skates, Bo R. Rueda, Ronny Drapkin, Samuel J. Klempner, Vikram Deshpande, David T. Ting, Michael P. Rout, John LaCava, David R. Walt, Kathleen H. Burns
Publikováno v:
bioRxiv
Improved biomarkers are needed for early cancer detection, risk stratification, treatment selection, and monitoring treatment response. While proteins can be useful blood-based biomarkers, many have limited sensitivity or specificity for these applic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cdcf66174cd5676ee31b3db57f28b9f
https://hdl.handle.net/11370/41ca3c33-d273-45a6-bf29-9274abc151ef
https://hdl.handle.net/11370/41ca3c33-d273-45a6-bf29-9274abc151ef
Publikováno v:
Marine Biotechnology. 23:430-444
Androgens stimulate ovarian development in eels. Our previous report indicated a correlation between the initial (debut) ovarian status (determined by kernel density estimation (KDE), presented as a probability density of oocyte size) and the consequ
Publikováno v:
BioTechniques, Vol 54, Iss 2, Pp 77-86 (2013)
MicroRNAs (miRs) regulate cellular processes by modulating gene expression. Although transcriptomic studies have identified numerous miRs differentially expressed in diseased versus normal cells, expression analysis alone cannot distinguish miRs driv
Externí odkaz:
https://doaj.org/article/3ffe6b7aa8b442dba6e746cd6842dc1d
Autor:
Wei-Chun Chung, Sheng-Yao Su, Wen-Chih Cheng, Shu-Hwa Chen, Chung Yen Lin, I-Hsuan Lu, Jan-Ming Ho, Pao-Yang Chen
Publikováno v:
BMC Genomics, Vol 21, Iss S3, Pp 1-8 (2020)
BMC Genomics
BMC Genomics
Background DNA methylation is a crucial epigenomic mechanism in various biological processes. Using whole-genome bisulfite sequencing (WGBS) technology, methylated cytosine sites can be revealed at the single nucleotide level. However, the WGBS data