Proenkephalin deletion in hematopoietic cells induces intestinal barrier failure resulting in clinical feature similarities with irritable bowel syndrome in mice.

Autor: Mas-Orea X; IRSD, Université de Toulouse, INSERM, INRAE, ENVT, Univ Toulouse III - Paul Sabatier (UPS), Toulouse, France., Rey L; IRSD, Université de Toulouse, INSERM, INRAE, ENVT, Univ Toulouse III - Paul Sabatier (UPS), Toulouse, France., Battut L; IRSD, Université de Toulouse, INSERM, INRAE, ENVT, Univ Toulouse III - Paul Sabatier (UPS), Toulouse, France., Bories C; INFINITy, Université de Toulouse, INSERM U1291, CNRS U5051, Univ Toulouse III - Paul Sabatier (UPS), Toulouse, France., Petitfils C; IRSD, Université de Toulouse, INSERM, INRAE, ENVT, Univ Toulouse III - Paul Sabatier (UPS), Toulouse, France., Abot A; IRSD, Université de Toulouse, INSERM, INRAE, ENVT, Univ Toulouse III - Paul Sabatier (UPS), Toulouse, France.; Enterosys SAS, Labège, France., Gheziel N; IRSD, Université de Toulouse, INSERM, INRAE, ENVT, Univ Toulouse III - Paul Sabatier (UPS), Toulouse, France.; INFINITy, Université de Toulouse, INSERM U1291, CNRS U5051, Univ Toulouse III - Paul Sabatier (UPS), Toulouse, France., Wemelle E; IRSD, Université de Toulouse, INSERM, INRAE, ENVT, Univ Toulouse III - Paul Sabatier (UPS), Toulouse, France., Blanpied C; IRSD, Université de Toulouse, INSERM, INRAE, ENVT, Univ Toulouse III - Paul Sabatier (UPS), Toulouse, France., Motta JP; IRSD, Université de Toulouse, INSERM, INRAE, ENVT, Univ Toulouse III - Paul Sabatier (UPS), Toulouse, France., Knauf C; IRSD, Université de Toulouse, INSERM, INRAE, ENVT, Univ Toulouse III - Paul Sabatier (UPS), Toulouse, France., Barreau F; IRSD, Université de Toulouse, INSERM, INRAE, ENVT, Univ Toulouse III - Paul Sabatier (UPS), Toulouse, France., Espinosa E; IRSD, Université de Toulouse, INSERM, INRAE, ENVT, Univ Toulouse III - Paul Sabatier (UPS), Toulouse, France., Aloulou M; INFINITy, Université de Toulouse, INSERM U1291, CNRS U5051, Univ Toulouse III - Paul Sabatier (UPS), Toulouse, France., Cenac N; IRSD, Université de Toulouse, INSERM, INRAE, ENVT, Univ Toulouse III - Paul Sabatier (UPS), Toulouse, France., Serino M; IRSD, Université de Toulouse, INSERM, INRAE, ENVT, Univ Toulouse III - Paul Sabatier (UPS), Toulouse, France., Mouledous L; Research Center on Animal Cognition (CRCA), Center of Integrative Biology (CBI), Université de Toulouse, CNRS UMR-5169, Univ Toulouse III - Paul Sabatier (UPS), Toulouse, France., Fazilleau N; INFINITy, Université de Toulouse, INSERM U1291, CNRS U5051, Univ Toulouse III - Paul Sabatier (UPS), Toulouse, France., Dietrich G; IRSD, Université de Toulouse, INSERM, INRAE, ENVT, Univ Toulouse III - Paul Sabatier (UPS), Toulouse, France. gilles.dietrich@inserm.fr.

Publikováno v: Communications biology [Commun Biol] 2023 Nov 16; Vol. 6 (1), pp. 1168. Date of Electronic Publication: 2023 Nov 16.

In Vivo Assessment of Antioxidant Potential of Human Milk Treated by Holder Pasteurization or High Hydrostatic Pressure Processing: A Preliminary Study on Intestinal and Hepatic Markers in Adult Mice.

Autor: Wemelle E; INSERM U1220, Institut de Recherche en Santé Digestive (IRSD), Université Paul Sabatier, Toulouse III, CHU Purpan, Place du Docteur Baylac, CS 60039, CEDEX 3, 31024 Toulouse, France.; European Associated Laboratory (EAL) «NeuroMicrobiota», International Research Projects (IRP) INSERM, 31024 Toulouse, France., Marousez L; Inserm, CHU Lille, U1286-INFINITE-Institute for Translational Research in Inflammation, University of Lille, 59000 Lille, France., Lesage J; Inserm, CHU Lille, U1286-INFINITE-Institute for Translational Research in Inflammation, University of Lille, 59000 Lille, France., De Lamballerie M; UMR CNRS 6144 GEPEA (Génie des Procédés Environnement-Agroalimentaire), ONIRIS, CS 82225, 44322 Nantes, France., Knauf C; INSERM U1220, Institut de Recherche en Santé Digestive (IRSD), Université Paul Sabatier, Toulouse III, CHU Purpan, Place du Docteur Baylac, CS 60039, CEDEX 3, 31024 Toulouse, France.; European Associated Laboratory (EAL) «NeuroMicrobiota», International Research Projects (IRP) INSERM, 31024 Toulouse, France., Carneiro L; INSERM U1220, Institut de Recherche en Santé Digestive (IRSD), Université Paul Sabatier, Toulouse III, CHU Purpan, Place du Docteur Baylac, CS 60039, CEDEX 3, 31024 Toulouse, France.; European Associated Laboratory (EAL) «NeuroMicrobiota», International Research Projects (IRP) INSERM, 31024 Toulouse, France.

Publikováno v: Antioxidants (Basel, Switzerland) [Antioxidants (Basel)] 2022 May 31; Vol. 11 (6). Date of Electronic Publication: 2022 May 31.

Camu-Camu Reduces Obesity and Improves Diabetic Profiles of Obese and Diabetic Mice: A Dose-Ranging Study.

Autor: Abot A; Enterosys SAS, 31670 Labège, France., Brochot A; A-Mansia Biotech SA, The Akkermansia Company, 1435 Mont-Saint-Guibert, Belgium., Pomié N; Enterosys SAS, 31670 Labège, France., Wemelle E; Institut National de la Santé et de la Recherche Médicale (INSERM), U1220, Institut de Recherche en Santé Digestive et Nutrition (IRSD), Université Paul Sabatier (UPS), 31000 Toulouse, France.; NeuroMicrobiota Lab, International Research Program (IRP) INSERM, 31000 Toulouse, France., Druart C; A-Mansia Biotech SA, The Akkermansia Company, 1435 Mont-Saint-Guibert, Belgium., Régnier M; WELBIO-Walloon Excellence in Life Sciences and BIOtechnology, Metabolism and Nutrition Research Group, Louvain Drug Research Institute, Université Catholique de Louvain (UCLouvain), 1200 Brussels, Belgium., Delzenne NM; WELBIO-Walloon Excellence in Life Sciences and BIOtechnology, Metabolism and Nutrition Research Group, Louvain Drug Research Institute, Université Catholique de Louvain (UCLouvain), 1200 Brussels, Belgium., de Vos WM; Laboratory of Microbiology, Wageningen University, 6708 WE Wageningen, The Netherlands.; Human Microbiome Research Program, Faculty of Medicine, University of Helsinki, 00014 Helsinki, Finland., Knauf C; Institut National de la Santé et de la Recherche Médicale (INSERM), U1220, Institut de Recherche en Santé Digestive et Nutrition (IRSD), Université Paul Sabatier (UPS), 31000 Toulouse, France.; NeuroMicrobiota Lab, International Research Program (IRP) INSERM, 31000 Toulouse, France., Cani PD; NeuroMicrobiota Lab, International Research Program (IRP) INSERM, 31000 Toulouse, France.; WELBIO-Walloon Excellence in Life Sciences and BIOtechnology, Metabolism and Nutrition Research Group, Louvain Drug Research Institute, Université Catholique de Louvain (UCLouvain), 1200 Brussels, Belgium.

Publikováno v: Metabolites [Metabolites] 2022 Mar 29; Vol. 12 (4). Date of Electronic Publication: 2022 Mar 29.

Interactions between the microbiota and enteric nervous system during gut-brain disorders.

Autor: Fried S; Université Paul Sabatier, Toulouse III, INSERM U1220, Institut de Recherche en Santé Digestive (IRSD), CHU Purpan, Place Du Docteur Baylac, CS 60039, 31024, Toulouse, Cedex 3, France; International Research Project (IRP), European Lab 'NeuroMicrobiota', Brussels/Toulouse, France., Wemelle E; Université Paul Sabatier, Toulouse III, INSERM U1220, Institut de Recherche en Santé Digestive (IRSD), CHU Purpan, Place Du Docteur Baylac, CS 60039, 31024, Toulouse, Cedex 3, France; International Research Project (IRP), European Lab 'NeuroMicrobiota', Brussels/Toulouse, France., Cani PD; International Research Project (IRP), European Lab 'NeuroMicrobiota', Brussels/Toulouse, France; UCLouvain, Université Catholique de Louvain, WELBIO Walloon Excellence in Life Sciences and BIOtechnology, Louvain Drug Research Institute, Metabolism and Nutrition Research Group, Brussels, Belgium., Knauf C; Université Paul Sabatier, Toulouse III, INSERM U1220, Institut de Recherche en Santé Digestive (IRSD), CHU Purpan, Place Du Docteur Baylac, CS 60039, 31024, Toulouse, Cedex 3, France; International Research Project (IRP), European Lab 'NeuroMicrobiota', Brussels/Toulouse, France. Electronic address: claude.knauf@inserm.fr.

Publikováno v: Neuropharmacology [Neuropharmacology] 2021 Oct 01; Vol. 197, pp. 108721. Date of Electronic Publication: 2021 Jul 15.

Identification of new enterosynes using prebiotics: roles of bioactive lipids and mu-opioid receptor signalling in humans and mice.

Autor: Abot A; IRSD, INSERM, Toulouse, Occitanie, France.; Enterosys, CRO, Toulouse, Occitanie, France.; European Associated Laboratory (EAL) NeuroMicrobiota, Toulouse, Brussels, France, Belgium., Wemelle E; IRSD, INSERM, Toulouse, Occitanie, France.; European Associated Laboratory (EAL) NeuroMicrobiota, Toulouse, Brussels, France, Belgium., Laurens C; CNRS, University of Strasbourg, Strasbourg, France.; CNES, Paris, France., Paquot A; Bioanalysis and Pharmacology of Bioactive Lipids Research Group, Louvain Drug Research Institute, UCLouvain, Université catholique de Louvain, Brussels, Belgium., Pomie N; Enterosys, CRO, Toulouse, Occitanie, France., Carper D; I2MC, INSERM, Toulouse, Occitanie, France., Bessac A; IRSD, INSERM, Toulouse, Occitanie, France.; IPBS, Toulouse, Midi-Pyrénées, France., Mas Orea X; IRSD, INSERM, Toulouse, Occitanie, France., Fremez C; Enterosys, CRO, Toulouse, Occitanie, France., Fontanie M; Enterosys, CRO, Toulouse, Occitanie, France., Lucas A; I2MC, INSERM, Toulouse, Occitanie, France., Lesage J; Lille 2 University of Health and Law, Lille, Hauts-de-France, France., Everard A; Metabolism and Nutrition Research Group, Louvain Drug Research Institute, Walloon Excellence in Life Sciences and BIOtechnology (WELBIO), UCLouvain, Université catholique de Louvain, Brussels, Belgium., Meunier E; IPBS, Toulouse, Midi-Pyrénées, France., Dietrich G; IRSD, INSERM, Toulouse, Occitanie, France., Muccioli GG; Bioanalysis and Pharmacology of Bioactive Lipids Research Group, Louvain Drug Research Institute, UCLouvain, Université catholique de Louvain, Brussels, Belgium., Moro C; I2MC, INSERM, Toulouse, Occitanie, France., Cani PD; European Associated Laboratory (EAL) NeuroMicrobiota, Toulouse, Brussels, France, Belgium claude.knauf@inserm.fr patrice.cani@uclouvain.be.; Metabolism and Nutrition Research Group, Louvain Drug Research Institute, Walloon Excellence in Life Sciences and BIOtechnology (WELBIO), UCLouvain, Université catholique de Louvain, Brussels, Belgium., Knauf C; IRSD, INSERM, Toulouse, Occitanie, France claude.knauf@inserm.fr patrice.cani@uclouvain.be.; European Associated Laboratory (EAL) NeuroMicrobiota, Toulouse, Brussels, France, Belgium.

Publikováno v: Gut [Gut] 2021 Jun; Vol. 70 (6), pp. 1078-1087. Date of Electronic Publication: 2020 Oct 05.