Orchestration of Tryptophan-Kynurenine Pathway, Acute Decompensation, and Acute-on-Chronic Liver Failure in Cirrhosis

Autor: Claria, J., Moreau, R., Fenaille, F., Amoros, A., Junot, C., Gronbaek, H., Coenraad, M.J., Pruvost, A., Ghettas, A., Chu-Van, E., Lopez-Vicario, C., Oettl, K., Caraceni, P., Alessandria, C., Trebicka, J., Pavesi, M., Deulofeu, C., Albillos, A., Gustot, T., Welzel, T.M., Fernandez, J., Stauber, R.E., Saliba, F., Butin, N., Colsch, B., Moreno, C., Durand, F., Nevens, F., Banares, R., Benten, D., Gines, P., Gerbes, A., Jalan, R., Angeli, P., Bernardi, M., Arroyo, V., EASL Clif Consortium, Grifols Chair European Fdn Study C

Publikováno v: Clària, J, Moreau, R, Fenaille, F, Amorós, A, Junot, C, Gronbaek, H, Coenraad, M J, Pruvost, A, Ghettas, A, Chu-Van, E, López-Vicario, C, Oettl, K, Caraceni, P, Alessandria, C, Trebicka, J, Pavesi, M, Deulofeu, C, Albillos, A, Gustot, T, Welzel, T M, Fernández, J, Stauber, R E, Saliba, F, Butin, N, Colsch, B, Moreno, C, Durand, F, Nevens, F, Bañares, R, Benten, D, Ginès, P, Gerbes, A, Jalan, R, Angeli, P, Bernardi, M, Arroyo, V & CANONIC Study Investigators of the EASL Clif Consortium Grifols Chair and the European Foundation for the Study of Chronic Liver Failure (EF Clif) 2019, ' Orchestration of Tryptophan-Kynurenine pathway, acute decompensation and acute-on-chronic liver failure in cirrhosis ', Hepatology, vol. 69, no. 4, pp. 1686-1701 . https://doi.org/10.1002/hep.30363
Hepatology, 69(4), 1686-1701
Hepatology
Hepatology, Wiley-Blackwell, 2019, 69 (4), pp.1686-1701. ⟨10.1002/hep.30363⟩
Hepatology, 69 (4
Hepatology, 2019, 69 (4), pp.1686-1701. ⟨10.1002/hep.30363⟩

Systemic inflammation (SI) is involved in the pathogenesis of acute decompensation (AD) and acute-on-chronic liver failure (ACLF) in cirrhosis. In other diseases, SI activates tryptophan (Trp) degradation through the kynurenine pathway (KP), giving r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc898f115816418b6c4fd3aa291c70a8
https://doi.org/10.1002/hep.30363

Ongoing liver inflammation in patients with chronic hepatitis C and sustained virological response

Autor: Welsch, C., Efinger, M., Wagner, M. von, Herrmann, E., Zeuzem, S., Welzel, T.M., Lange, C.M.

Background: Novel direct-acting antiviral DAA combination therapies tremendously improved sustained virologic response (SVR) rates in patients with chronic HCV infection. SVR is typically accompanied by normalization of liver enzymes, however, hepati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______610::10ac6f332918bef2c26a10512b225a6f
https://publica.fraunhofer.de/handle/publica/254349

FRI-450 - Liver Transplantation for Chronic HCV Infection in the United States 2002-2014: An Analysis of the UNOS/OPTN Database

Autor: Dultz, G., Graubard, B., Martin, P., Welker, M.W., Borg, B., Zeuzem, S., McGlynn, K.A., Welzel, T.M.

Publikováno v: In Journal of Hepatology 2016 64(2) Supplement:S537-S537

P0896 : Long-term follow-up analysis of RAVs in HCV NS3, NS5A, and NS5B in daa therapy failure patients

Autor: Susser, S., Würzburg, J., Kofler, S., Welzel, T.M., Perner, D., Zeuzem, S., Sarrazin, C.

Publikováno v: In Journal of Hepatology April 2015 62 Supplement 2:S679-S680

P0661 : Prediction of HBeAg seroconversion in HBeAg-positive chronic hepatitis B patients treated with entecavir using ALT and platelet count: Results from a large european multi-center study

Autor: Chi, H., van Bömmel, F., Buti, M., Brown, A., Carey, I., Fasano, M., Mutimer, D., Deterding, K., Oo, Y., Arends, P., de Knegt, R.J., Santantonio, T., Welzel, T.M., Pradat, P., Petersen, J., Wedemeyer, H., Berg, T., Zoulim, F., Hansen, B.E., Janssen, H.L

Publikováno v: In Journal of Hepatology April 2015 62 Supplement 2:S568-S568