Serum snoRNAs as biomarkers for joint ageing and post traumatic osteoarthritis

Autor: Steinbusch, MMF, Fang, Y, Milner, PI, Clegg, PD, Young, DA, Welting, TJM, Peffers, MJ

Publikováno v: Scientific Reports, 7:43558. Nature Publishing Group
Scientific reports

The development of effective treatments for the age-related disease osteoarthritis and the ability to predict disease progression has been hampered by the lack of biomarkers able to demonstrate the course of the disease. Profiling the expression patt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b3170af537b0cf0573d19c52a9dcdfb1
https://cris.maastrichtuniversity.nl/en/publications/c84712e6-0aec-4d58-85cd-4fcf47a4a3a9

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Cell-integrated serum-induced signalling patterns can differentiate between hand and knee osteoarthritis patients.

Autor: Neefjes M; Department of Rheumatology, Radboud University Medical Center, Nijmegen, The Netherlands., Housmans BAC; Laboratory for Experimental Orthopedics, Department of Orthopedic Surgery, Maastricht University, Maastricht, The Netherlands., Kaffa C; Center for Molecular and Biomolecular Informatics, Radboud University Medical Center, Nijmegen, The Netherlands., Thielen NGM; Department of Rheumatology, Radboud University Medical Center, Nijmegen, The Netherlands., Joosten LAB; Department of Internal Medicine, Radboud Institute of Molecular Life Sciences (RIMLS), Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Medical Genetics, Iuliu Hatieganu Unversity of Medicine and Pharmacy, Cluj-Napoca, Romania., van den Ende CHM; Department of Rheumatology, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Rheumatology, Sint Maartenskliniek, Nijmegen, The Netherlands., Vitters EL; Department of Rheumatology, Radboud University Medical Center, Nijmegen, The Netherlands., van den Akker GGH; Laboratory for Experimental Orthopedics, Department of Orthopedic Surgery, Maastricht University, Maastricht, The Netherlands., Welting TJM; Laboratory for Experimental Orthopedics, Department of Orthopedic Surgery, Maastricht University, Maastricht, The Netherlands.; Laboratory for Experimental Orthopedics, Department of Orthopedic Surgery, Maastricht University Medical Center, Maastricht, The Netherlands., van Caam APM; Department of Rheumatology, Radboud University Medical Center, Nijmegen, The Netherlands., van der Kraan PM; Department of Rheumatology, Radboud University Medical Center, Nijmegen, The Netherlands.

Publikováno v: Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2024 Nov 18. Date of Electronic Publication: 2024 Nov 18.

Discovery of calcite as a new pro-inflammatory calcium-containing crystal in human osteoarthritic synovial fluid.

Autor: Niessink T; Department of Rheumatology, VieCuri Medical Centre, Tegelseweg 210, 5912 BL Venlo, the Netherlands; Personalized Therapeutics and Diagnostics, Department of Bioengineering Technology, University of Twente, Drienerlolaan 5, 7522 NB Enschede, the Netherlands. Electronic address: t.niessink@utwente.nl., Stassen RHMJ; Department of Experimental Orthopaedics, Maastricht University Medical Centre, P. Debyelaan 25, 6229 HX Maastricht, the Netherlands., Kischkel B; Department of Internal Medicine, Radboud University Medical Centre, Geert Grooteplein Zuid 8, 6525 GA Nijmegen, the Netherlands., Vuscan P; Department of Internal Medicine, Radboud University Medical Centre, Geert Grooteplein Zuid 8, 6525 GA Nijmegen, the Netherlands., Emans PJ; Department of Experimental Orthopaedics, Maastricht University Medical Centre, P. Debyelaan 25, 6229 HX Maastricht, the Netherlands., van den Akker GGH; Department of Experimental Orthopaedics, Maastricht University Medical Centre, P. Debyelaan 25, 6229 HX Maastricht, the Netherlands., Janssen M; Department of Rheumatology, VieCuri Medical Centre, Tegelseweg 210, 5912 BL Venlo, the Netherlands., Joosten LAB; Department of Internal Medicine, Radboud University Medical Centre, Geert Grooteplein Zuid 8, 6525 GA Nijmegen, the Netherlands; Department of Medical Genetics, Iuliu Hatieganu University of Medicine and Pharmacy, Str. Pasteur, Nr. 6, 400012 Cluj-Napoca, Romania., Otto C; Personalized Therapeutics and Diagnostics, Department of Bioengineering Technology, University of Twente, Drienerlolaan 5, 7522 NB Enschede, the Netherlands., Welting TJM; Department of Experimental Orthopaedics, Maastricht University Medical Centre, P. Debyelaan 25, 6229 HX Maastricht, the Netherlands., Jansen TL; Department of Rheumatology, VieCuri Medical Centre, Tegelseweg 210, 5912 BL Venlo, the Netherlands.

Publikováno v: Osteoarthritis and cartilage [Osteoarthritis Cartilage] 2024 Oct; Vol. 32 (10), pp. 1261-1272. Date of Electronic Publication: 2024 May 26.