Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Wells W. Magargal"'
Autor:
William C. Olson, Wells W. Magargal, Vincent A. DiPippo, Sameer M. Moorji, Jose D. Murga, Amy Han
Publikováno v:
The Prostate. 75:242-254
BACKGROUND Antibody–drug conjugates (ADCs) are an emerging class of cancer therapies that have demonstrated favorable activity both as single agents and as components of combination regimens. Phase 2 testing of an ADC targeting prostate-specific me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59a486e6e3047751b27cbf559bf2b407
https://doi.org/10.1002/pros.22910
https://doi.org/10.1002/pros.22910
Autor:
Dangshe Ma, Gerald P. Donovan, Andre Marozsan, William C. Olson, Kirsten A. Nagashima, Robert R. Arrigale, Paul J. Maddon, Brian Kennedy, Yun Kenneth Kang, Wells W. Magargal
Publikováno v:
The Journal of Infectious Diseases. 206:706-713
The spore-forming bacterium Clostridium difficile represents the principal cause of hospital-acquired diarrhea and pseudomembranous colitis worldwide. C. difficile infection (CDI) is mediated by 2 bacterial toxins, A and B; neutralizing these toxins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::977a09303abf526ea0dc331a81da64f6
https://doi.org/10.1093/infdis/jis416
https://doi.org/10.1093/infdis/jis416
Autor:
Jose D, Murga, Sameer M, Moorji, Amy Q, Han, Wells W, Magargal, Vincent A, DiPippo, William C, Olson
Publikováno v:
The Prostate. 75(3)
Antibody-drug conjugates (ADCs) are an emerging class of cancer therapies that have demonstrated favorable activity both as single agents and as components of combination regimens. Phase 2 testing of an ADC targeting prostate-specific membrane antige
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::66076553fbbac50f1fbee872a02c5b07
https://pubmed.ncbi.nlm.nih.gov/25327687
https://pubmed.ncbi.nlm.nih.gov/25327687
Publikováno v:
Cancer Research. 74:798-798
Introduction: Androgen receptor (AR), the PI3K/mTOR signaling pathway and prostate-specific membrane antigen (PSMA) represent significant potential targets for prostate cancer therapy. The present study examined the cross-regulation and co-targeting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55770f19c16977b1b42aceb6d70117ee
https://doi.org/10.1158/1538-7445.am2014-798
https://doi.org/10.1158/1538-7445.am2014-798
Autor:
Dena Marrinucci, Florence Y. Lee, Amanda K. L. Anderson, Angela Yu, Vincent A. DiPippo, Wells W. Magargal, William C. Olson
Publikováno v:
Journal of Clinical Oncology. 32:266-266
266 Background: Prostate-specific membrane antigen (PSMA) is expressed ubiquitously in prostate adenocarcinoma, and the intensity of expression increases with disease aggressiveness. Exploiting PSMA for therapy could potentially be aided by a minimal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::106815ad5ecad6e2d4c9153c93b5681a
https://doi.org/10.1200/jco.2014.32.4_suppl.266
https://doi.org/10.1200/jco.2014.32.4_suppl.266
Publikováno v:
Molecular Cancer Therapeutics. 12:A262-A262
Introduction: Recent approvals of new prostate cancer (PCa) drugs and a growing number of pipeline agents have created opportunities for designing rational drug combinations. Potent antiandrogens such as enzalutamide and abiraterone affect expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::203da78e97364e45b901a852080a148d
https://doi.org/10.1158/1535-7163.targ-13-a262
https://doi.org/10.1158/1535-7163.targ-13-a262
Publikováno v:
Journal of Clinical Oncology. 31:e16007-e16007
e16007 Background: Recent approvals of four new prostate cancer (PCa) drugs and a growing number of pipeline agents have created opportunities for designing rational drug combinations. Potent antiandrogens such as enzalutamide and abiraterone affect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::242a44340ea35be6c14327fadb445327
https://doi.org/10.1200/jco.2013.31.15_suppl.e16007
https://doi.org/10.1200/jco.2013.31.15_suppl.e16007
Abstract 3668: Single-dose activity of PSMA ADC against prostate cancer xenograft and explant tumors
Autor:
William C. Olson, Wells W. Magargal
Publikováno v:
Cancer Research. 71:3668-3668
Introduction: Prostate-specific membrane antigen (PSMA) is an attractive target for antibody-targeted therapy of prostate cancer due to its abundant and selective expression on the surface of prostate cancer cells. We have generated a novel antibody-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8363a6d1711f89dd727073096f9a58e5
https://doi.org/10.1158/1538-7445.am2011-3668
https://doi.org/10.1158/1538-7445.am2011-3668
Publikováno v:
Proceedings of the National Academy of Sciences. 76:2532-2535
In populations of cultured arterial endothelial and smooth muscle cells grown under the same conditions, we have measured the total activity per cell of 10 enzymes commonly used as "markers" for subcellular organelles: NADH: ferricyanide reductase, N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fd1f4b4878b677891ca29a835ee1086
https://doi.org/10.1073/pnas.76.6.2532
https://doi.org/10.1073/pnas.76.6.2532
Autor:
Shin Lin, Wells W. Magargal
Transformation of chicken embryo fibroblasts by infection with Rous sarcoma virus has been shown to cause disruption of actin filament organization as seen with fluorescence staining techniques. This study is an attempt to use quantitative biochemica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fbf647d5d0def162bd40bdd66f92c34
https://europepmc.org/articles/PMC386895/
https://europepmc.org/articles/PMC386895/
