Zobrazeno 1 - 10
of 2 085
pro vyhledávání: '"Wells, W."'
Autor:
Ortega-Rodriguez, Uriel, Bettinger, John Q., Zou, Guozhang, Falkowski, Vincent M., Lehtimaki, Mari, Matthews, Alicia M., Biel, Thomas G., Pritts, Jordan D., Wu, Wells W., Shen, Rong-Fong, Agarabi, Cyrus, Rao, V. Ashutosh, Xie, Hang, Ju, Tongzhong
Publikováno v:
In Cell Reports Methods 19 August 2024 4(8)
Autor:
Cecily Choy, Joseph Chen, Jiangyuan Li, D. Travis Gallagher, Jian Lu, Daichao Wu, Ainslee Zou, Humza Hemani, Beverly A. Baptiste, Emily Wichmann, Qian Yang, Jeffrey Ciffelo, Rui Yin, Julia McKelvy, Denise Melvin, Tonya Wallace, Christopher Dunn, Cuong Nguyen, Chee W. Chia, Jinshui Fan, Jeannie Ruffolo, Linda Zukley, Guixin Shi, Tomokazu Amano, Yang An, Osorio Meirelles, Wells W. Wu, Chao-Kai Chou, Rong-Fong Shen, Richard A. Willis, Minoru S. H. Ko, Yu-Tsueng Liu, Supriyo De, Brian G. Pierce, Luigi Ferrucci, Josephine Egan, Roy Mariuzza, Nan-Ping Weng
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract The resolution of SARS-CoV-2 replication hinges on cell-mediated immunity, wherein CD8+ T cells play a vital role. Nonetheless, the characterization of the specificity and TCR composition of CD8+ T cells targeting non-spike protein of SARS-C
Externí odkaz:
https://doaj.org/article/963224e732b44fa8b3d0805dabc27063
We propose a unified appearance model accounting for traditional shallow (i.e. 3D SIFT keypoints) and deep (i.e. CNN output layers) image feature representations, encoding respectively specific, localized neuroanatomical patterns and rich global info
Externí odkaz:
http://arxiv.org/abs/2010.04283
Autor:
Shufeng Liu, Charles B. Stauft, Prabhuanand Selvaraj, Prabha Chandrasekaran, Felice D’Agnillo, Chao-Kai Chou, Wells W. Wu, Christopher Z. Lien, Clement A. Meseda, Cyntia L. Pedro, Matthew F. Starost, Jerry P. Weir, Tony T. Wang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Examples of effective live attenuated viral vaccines include the measles, mumps and rubella vaccine, as well as the chickenpox vaccine. In this work, the authors engineer a live attenuated SARS-CoV-2 virus that demonstrates attenuation in numerous in
Externí odkaz:
https://doaj.org/article/d66b9234e9e141358ff5e53841cc746b
Akademický článek
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Autor:
So Jin Bing, Sune Justesen, Wells W. Wu, Abdul Mohin Sajib, Stephanee Warrington, Alan Baer, Stephan Thorgrimsen, Rong-Fong Shen, Ronit Mazor
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 24, Iss , Pp 255-267 (2022)
Despite the high safety profile demonstrated in clinical trials, the immunogenicity of adeno-associated virus (AAV)-mediated gene therapy remains a major hurdle. Specifically, T-cell-mediated immune responses to AAV vectors are related to loss of eff
Externí odkaz:
https://doaj.org/article/1b0e9853740c409c867ea3011ba44dc8
Publikováno v:
eLife, Vol 12 (2023)
Newborns are unable to reach the adult-level humoral immune response partly due to the potent immunoregulatory role of IL-10. Increased IL-10 production by neonatal B cells has been attributed to the larger population of IL-10-producting CD43+ B-1 ce
Externí odkaz:
https://doaj.org/article/fd02de73280644fe9435795f9e7b3524
Akademický článek
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Autor:
Xiaoping Sun, Thomas Nguyen, Achouak Achour, Annette Ko, Jeffrey Cifello, Chen Ling, Jay Sharma, Toyoko Hiroi, Yongqing Zhang, Chee W. Chia, William Wood III, Wells W. Wu, Linda Zukley, Je-Nie Phue, Kevin G. Becker, Rong-Fong Shen, Luigi Ferrucci, Nan-ping Weng
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 17 (2022)
A diverse T cell receptor (TCR) repertoire is essential for protection against a variety of pathogens, and TCR repertoire size is believed to decline with age. However, the precise size of human TCR repertoires, in both total and subsets of T cells,
Externí odkaz:
https://doaj.org/article/be9e3fbb629f4693b28c5ccd2679bf6e
Characterization of protein unable to bind von Willebrand factor in recombinant factor VIII products
Autor:
Chun, Haarin, Pettersson, John R., Shestopal, Svetlana A., Wu, Wells W., Marakasova, Ekaterina S., Olivares, Philip, Surov, Stepan S., Ovanesov, Mikhail V., Shen, Rong‐Fong, Sarafanov, Andrey G. *
Publikováno v:
In Journal of Thrombosis and Haemostasis April 2021 19(4):954-966