The mammalian Ire1 inhibitor, 4µ8C, exhibits broad anti- Aspergillus activity in vitro and in a treatment model of fungal keratitis.

Autor: Kamath, Manali M., Adams, Emily M., Lightfoot, Jorge D., Wells, Becca L., Fuller, Kevin K.

Publikováno v: Frontiers in Cellular & Infection Microbiology; 2024, p1-12, 12p

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The mammalian Ire1 inhibitor, 4μ8C, exhibits broad anti- Aspergillus activity in vitro and in a treatment model of fungal keratitis.

Autor: Kamath MM; Department of Microbiology & Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK., Adams EM; Department of Ophthalmology, University of Oklahoma Health Sciences Center, Oklahoma City, OK., Lightfoot JD; Department of Ophthalmology, University of Oklahoma Health Sciences Center, Oklahoma City, OK., Wells BL; Department of Microbiology & Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK., Fuller KK; Department of Microbiology & Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK.; Department of Ophthalmology, University of Oklahoma Health Sciences Center, Oklahoma City, OK.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Aug 08. Date of Electronic Publication: 2024 Aug 08.