Evaluation of covariate effects in item response theory models

Autor: Gustaf J. Wellhagen, Ashraf Yassen, Dirk Garmann, Astrid Bröker, Alexander Solms, Yang Zhang, Maria C. Kjellsson, Mats O. Karlsson

Publikováno v: CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 5, Pp 812-822 (2024)

Abstract Item response theory (IRT) models are usually the best way to analyze composite or rating scale data. Standard methods to evaluate covariate or treatment effects in IRT models do not allow to identify item‐specific effects. Finding subgrou

Externí odkaz: https://doaj.org/article/0139e12916414106b4d7f91451e70005

Item response theory analysis of daytime sleepiness as a symptom of obstructive sleep apnea.

Autor: Wellhagen, Gustaf J.¹ (AUTHOR), Karlsson, Mats O.¹ (AUTHOR) mats.karlsson@farmaci.uu.se, Kjellsson, Maria C.¹ (AUTHOR), Garmann, Dirk² (AUTHOR), Bröker, Astrid² (AUTHOR), Zhang, Yang² (AUTHOR), Nokela, Mika² (AUTHOR), Weimann, Gerrit^2,3 (AUTHOR), Yassen, Ashraf² (AUTHOR)

Publikováno v: CPT: Pharmacometrics & Systems Pharmacology. May2024, Vol. 13 Issue 5, p880-890. 11p.

The burden of critical illness among adults in a Swedish region—a population-based point-prevalence study

Autor: Carl Otto Schell, Andreas Wellhagen, Miklós Lipcsey, Lisa Kurland, Petronella Bjurling-Sjöberg, Cecilia Stålsby Lundborg, Markus Castegren, Tim Baker

Publikováno v: European Journal of Medical Research, Vol 28, Iss 1, Pp 1-9 (2023)

Abstract Background Patients with critical illness have a high risk of mortality. Key decision-making in the health system affecting the outcomes of critically ill patients requires epidemiological evidence, but the burden of critical illness is larg

Externí odkaz: https://doaj.org/article/8892e9d5ce0a423eab56f2ff9ce87071

Essential Emergency and Critical Care: a consensus among global clinical experts

Autor: Samuel Akech, Mike English, Thomas G Weiser, Adam D Laytin, Niranjan Kissoon, Jaran Eriksen, Lovenish Bains, Fred Bulamba, Claudia Hanson, Maria Jirwe, Jolene Moore, Mpoki Ulisubisya, Vincent Ioos, Kent Doi, Lee A Wallis, Tom Bashford, Kapil Dev Soni, Nobhojit Roy, Franco Diaz, Mulinda Nyirenda, Nicholas Risko, Hendry R Sawe, Jacob McKnight, Alexandra Wharton-Smith, Jamie Rylance, Monty Khajanchi, Gavin Wooldridge, Emmanuel Fru Nsutebu, Lisa Kurland, Peter Baker, John C Marshall, Kathryn Rowan, Usha Lalla, Balasubramanian Venkatesh, Cornelius Sendagire, Neill KJ Adhikari, Tim Baker, Brian Rice, Josephine Langton, Elisabeth Riviello, Fiona Muttalib, Francis Mupeta, Jacquie Oliwa, Stefan Swartling Peterson, Andrew G Smith, Lorna Guinness, Megan Cox, Wim Van Damme, John Kellett, Elizabeth M Molyneux, Richard Venn, Andrea B Pembe, Mervyn Mer, Ignacio Martin-Loeches, Raymond Towey, Lina Zhang, Blaise Pascal, Hiral A Shah, Carl Otto Schell, Karima Khalid, Paul D Sonenthal, Alex Sanga, Raphael K. Kayambankadzanja, Adam Asghar, Adrian J Holloway, Ahmed Rhassane El Adib, Alexia Michaelides, Alvaro Coronado Munoz, Amos Muzuka, Analía Fernández, Andreas Wellhagen, Anita Gadgil, Anna Hvarfner, Anuja Abayadeera, Asya Agulnik, Aurélie Godard, Bargo Mahamat Yousif, Bhakti Sarang Ben Morton, Bharath Kumar, Tirupakuzhi Vijayaraghavan, Bobby King, C Louise Thwaites, Chian Wern Tai, Christian Owoo, Dan Brun Petersen, Daniel Tatay, David Lee Skinner, Denis Kinyua, Dhruva Ghosh, Diptesh Aryal, Donald Mlombwa, Duyen Thi, Hanh Bui, Edwin R Lugazia, Ellena Heyns, Erika Montalvo, Ernesto Gerardo Moreno, Esther Banda Kanyangira, Furaha Nzanzu, Gibonce Mwakisambwe, Guy A Richards, Hala Ammar, Halinder S Mangat, Hasanein H Ghali, Hoi Ping Shum, Ibrahim Salim Abdullahi, Ingrid T von der Osten, James S Lee, Jane Kasozi Namagga, Jasmine Armour-Marshall, John Z Metcalfe, Jonas Blixt, Juan Gutierrez Mejia, Juan Ignacio Silesky-Jiménez, Karl Martin Kohne, Kazuhiro Yokobatake, Kristina E. Rudd, Kwame Asante Akuamoah-Boateng, Lars Irestedt, Lia I Losonczy, Margaret Nyaika, Markus Castegren, Matthew Loftus, Matti Reinikainen, Michael Jaung, Michael S Lipnick, Miklos Lipcey, Märit Amanda Halmin, Naman Shah, Natalie L Cobb, Nathan D Nielsen, Neville Vlok, Ntogwiachu Daniel Kobuh, Oscar Fernández Rostello, Patricia Duque, Paul Patrick Mwasapi, Petronella Bjurling-Sjöberg, Piedad Sarmiento, Pryanka Relan, Rebecca Silvers, Rehema Mlay, Rich Branson, Richard J Wang, Richard Kojan, Richard Peter Von Rahden, Rob Mac Sweeney, Rodrigo Genaro Arduini, Rodwell Gundo, Ruyumbu Sixtus, Samson Kwazizira Mndolo, Shada A. Rouhani, Siriel Nanzia Massawe, Steven A Webb, Sunkaru Touray, Susana Guido, Teresa Kortz, Theodoros Aslanidis, Traci A Wolbrink, V Theodore Barnett, Vijay Christopher Kannan, Waleed S Eldebsy, Wangari Waweru-Siika, Wezzie Kumwenda Mwafulirwa, William Obeng, Yasein Omer, Zione Banda

Publikováno v: BMJ Global Health, Vol 6, Iss 9 (2021)

Background Globally, critical illness results in millions of deaths every year. Although many of these deaths are potentially preventable, the basic, life-saving care of critically ill patients are often overlooked in health systems. Essential Emerge

Externí odkaz: https://doaj.org/article/de5537511f7749b889a3e7d97b1f863c

Using a semi‐mechanistic model to identify the main sources of variability of metformin pharmacokinetics.

Autor: Stage, Tore Bjerregaard^1,2, Wellhagen, Gustaf², Christensen, Mette Marie Hougaard³, Guiastrennec, Benjamin², Brøsen, Kim¹, Kjellsson, Maria C.² maria.kjellsson@farmbio.uu.se

Publikováno v: Basic & Clinical Pharmacology & Toxicology. Jan2019, Vol. 124 Issue 1, p105-114. 10p.