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The accumulation of soluble and insoluble amyloid-beta (A-beta) in the brain indicates failure of elimination of A-beta from the brain with age and Alzheimer's disease. There is a variety of mechanisms for elimination of A-beta from the brain. They i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bccaa46c55becaf59fda63902157d8c2
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 106:32-41
Five groups of neonatal pigs were subjected to cardiopulmonary bypass with circulatory arrest periods that varied from 70 to 120 minutes for the investigation of brain changes in induced deep-core hypothermia (15° C) with circulatory arrest. The par
Publikováno v:
Cardiovascular Surgery. 1:155-160
Twenty-four neonatal pigs were exposed to periods of circulatory arrest of between 70 and 120 min under profound hypothermia at 15°C. Brain tissue taken 6h after cardiopulmonary bypass was examined histologically and by electron microscopy for evide
Autor:
M V Venetikou, Thomas Vl, S. R. Bloom, Weller Ro, I. T. Fessatidis, Shore Df, F. Goodland, Hunt Rh, D. Rowe
Publikováno v:
European Journal of Cardio-Thoracic Surgery. 7:465-473
To investigate brain changes in induced deep core hypothermia (15 °C) with circulatory arrest, five groups of neonatal pigs were subjected to cardiopulmonary bypass (CPB), with circulatory arrest (CA) periods varying from 70- 120 min. The parameters
Autor:
Yu-Min Kuo, Beach, Tg, Sue, Li, Scott, S., Layne, Kj, Kokjohn, Ta, Kalback, Wm, Luehrs, Dc, Vishnivetskaya, Ta, Abramowski, D., Sturchler-Pierrat, C., Staufenbiel, M., Weller, Ro, Roher, Ae
Publikováno v:
ResearcherID
BACKGROUND: High levels of A beta in the cerebral cortex distinguish demented Alzheimer's disease (AD) from nondemented elderly individuals, suggesting that decreased amyloid-beta (A beta) peptide clearance from the brain is a key precipitating facto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c347bdab8a97ad2cf7862c49758fb46d
https://europepmc.org/articles/PMC1950067/
https://europepmc.org/articles/PMC1950067/
Publikováno v:
Scopus-Elsevier
ResearcherID
ResearcherID
BACKGROUND: Amyloid-beta (A beta) accumulates in plaques and as cerebral amyloid angiopathy (CAA) in the brains of both Alzheimer's disease (AD) patients and transgenic A betaPPswe/tg2576 (tg2576) mice. Increasingly, evidence in humans and mice shows
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6becff2e4afddff3e87d8a9512e115df
https://europepmc.org/articles/PMC1949958/
https://europepmc.org/articles/PMC1949958/
There is evidence for lymphatic drainage of interstitial fluid from the brain along perivascular spaces in a number of mammalian species. Ultrastructural studies suggest that there are similar drainage pathways in the human cerebral cortex. Perivascu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b7c71cfeac1154c7fab43b51dbbd145
https://europepmc.org/articles/PMC1467691/
https://europepmc.org/articles/PMC1467691/
Autor:
Weller Ro
Publikováno v:
Neuropathology and applied neurobiology. 23(1)
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