Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Weldon B. Jolley"'
Autor:
Donald F Smee, Howard B Cottam, Brahma S Sharma, Ganesh D Kini, Ganapathi R Revankar, Emmanuel A Ojo-Amaize, Robert W Sidwell, Weldon B Jolley, Roland K Robins
Publikováno v:
Canadian Journal of Infectious Diseases, Vol 3, Iss Suppl B, Pp 41-48 (1992)
7-thia-8-oxoguanosine (TOGuo) is the first reported structure of a family of modified guanosine analogues exhibiting antiviral activity in rodent models. Its spectrum of action includes interferon-sensitive viruses such as alphaviruses, bunyaviruses,
Externí odkaz:
https://doaj.org/article/c4c9e5228dba4f8a9eceddc11c64aceb
Autor:
Arend Mulder, Weldon B. Jolley, Johan W. Bruning, Cornelis J. M. Melief, Joke Blom, M.J. Kardol
Publikováno v:
Human Immunology. 36:186-192
We have developed an in vitro immunization system for the production of B-cell lines that secrete HLA-specific human mAbs. For this purpose, peripheral blood lymphocytes of parous women were stimulated with pools of allogeneic lymphocytes. Preferenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f704ee755d7b8012d836aeed1b8eb59
https://doi.org/10.1016/0198-8859(93)90124-j
https://doi.org/10.1016/0198-8859(93)90124-j
Autor:
Roland K. Robins, Brahma S. Sharma, Howard B. Cottam, Ganesh D. Kini, Weldon B. Jolley, Donald F. Smee, Ganapathi R. Revankar, Robert W. Sidwell, Emmanuel A. Ojo-Amaize
Publikováno v:
Canadian Journal of Infectious Diseases, Vol 3, Iss Suppl B, Pp 41-48 (1992)
7-thia-8-oxoguanosine (TOGuo) is the first reported structure of a family of modified guanosine analogues exhibiting antiviral activity in rodent models. Its spectrum of action includes interferon-sensitive viruses such as alphaviruses, bunyaviruses,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e65a776433baf56baebb3d083b3e490
https://doi.org/10.1155/1992/382672
https://doi.org/10.1155/1992/382672
Publikováno v:
Cellular Immunology. 126:414-419
Intraperitoneal treatment of mice with a novel guanosine analog, 7-thia-8-oxoguanosine (7-thia-8-oxoGuo), gives rise to activated splenic lymphocytes and peritoneal macrophages with enhanced capacity to mediate antibody-dependent cellular cytotoxicit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5a2d0c663611665f714d4413260e3a7
https://doi.org/10.1016/0008-8749(90)90332-l
https://doi.org/10.1016/0008-8749(90)90332-l
Autor:
Steven B. Larson, Ganesh D. Kini, Roland K. Robins, Birendra K. Bhattacharya, Steven S. Matsumoto, Yogesh S. Sanghvi, Ganapathi R. Revankar, Weldon B. Jolley
Publikováno v:
Journal of Medicinal Chemistry. 33:336-344
A series of 1,2,3-triazole (2), pyrazole (3 and 5), and pyrrole (4) ribonucleosides with two adjacent carbamoyl groups have been synthesized and evaluated for cell growth inhibition and induction of cellular differentiation of HL-60 cells in culture.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d00fc1ad709e5c6f769c2185ffd81544
https://doi.org/10.1021/jm00163a054
https://doi.org/10.1021/jm00163a054
Autor:
Thomas L. Avery, Boanerges Rubalcava, Roland K. Robins, Steven S. Matsumoto, Howard B. Cottam, Weldon B. Jolley, Emmanuel A. Ojo-Amaize
Publikováno v:
Immunology Letters. 23:173-178
The capacity of certain guanine ribonucleosides (modified at the 7 and/or 8 positions) to enhance the respiratory burst of murine peritoneal phagocytes was evaluated. The results show that 8-mercaptoguanosine, 8-bromoguanosine, 7-methyl-8-oxoguanosin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ef71fe79983d4f281e2335f6d9e626f
https://doi.org/10.1016/0165-2478(90)90187-u
https://doi.org/10.1016/0165-2478(90)90187-u
Publikováno v:
Tissue antigens. 42(1)
In vitro immunization and subsequent immortalization of peripheral blood cells of a multiparous woman has resulted in the production of a stable human mouse heterohybridoma, 5C2A2, secreting an HLA-A2/A28-specific human monoclonal antibody. Although
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd59d85cda5a320a5e100124d43a8cbe
https://pubmed.ncbi.nlm.nih.gov/7504327
https://pubmed.ncbi.nlm.nih.gov/7504327
Publikováno v:
Clinicalexperimental metastasis. 9(5)
We have recently reported that a synthetic nucleoside, 7-thia-8-oxoguanosine (7T8OG) is a potent activator of a number of effectors which are involved in anti-tumor immune responses. 7T8OG was found to induce interferon (IFN) production, to activate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07f54d043212650583bac7767443be4e
https://pubmed.ncbi.nlm.nih.gov/1914279
https://pubmed.ncbi.nlm.nih.gov/1914279
Publikováno v:
Antiviral research. 13(2)
7-Thia-8-oxoguanosine is a novel biological response modifier with broad-spectrum antiviral activity against many DNA and RNA viruses in vivo. Since two of its properties are to induce interferon and to activate natural killer (NK) cells, we investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57f7c93cb90839967eb069fc6873fd72
https://pubmed.ncbi.nlm.nih.gov/1693058
https://pubmed.ncbi.nlm.nih.gov/1693058
Autor:
K Nagahara, Ganesh D. Kini, Brahma S. Sharma, Roland K. Robins, Jack D. Anderson, Steven B. Larson, N. K. Dalley, Donald F. Smee, Weldon B. Jolley, Ai Jin
Publikováno v:
Journal of medicinal chemistry. 33(1)
Novel analogues of the naturally occurring purine nucleosides were synthesized in the thiazolo[4,5-d]pyrimidine ring system to determine the immunomodulatory effects of insertion of a sulfur atom in place of nitrogen at position 7 of the purine ring.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbfabd5d9b10012e17768e5f56a148ad
https://pubmed.ncbi.nlm.nih.gov/2153211
https://pubmed.ncbi.nlm.nih.gov/2153211