Novel Selection Approaches to Identify Antibodies Targeting Neoepitopes on the C5b6 Intermediate Complex to Inhibit Membrane Attack Complex Formation.

Autor: Stach L; Biopharm Discovery, GlaxoSmithKline, Gunnels Wood Road, Stevenage SG1 2NY, UK., Dinley EKH; Biopharm Discovery, GlaxoSmithKline, Gunnels Wood Road, Stevenage SG1 2NY, UK., Tournier N; Biopharm Discovery, GlaxoSmithKline, Gunnels Wood Road, Stevenage SG1 2NY, UK., Bingham RP; Screening, Profiling and Mechanistic Biology, GlaxoSmithKline, Gunnels Wood Road, Stevenage SG1 2NY, UK., Gormley DA; Immunology Research Unit, GlaxoSmithKline, Gunnels Wood Road, Stevenage SG1 2NY, UK., Bramhall JL; Immunology Research Unit, GlaxoSmithKline, Gunnels Wood Road, Stevenage SG1 2NY, UK., Taylor A; Clinical Pharmacology & Experimental Medicine, GlaxoSmithKline, Gunnels Wood Road, Stevenage SG1 2NY, UK., Clarkson JE; Biopharm Discovery, GlaxoSmithKline, Gunnels Wood Road, Stevenage SG1 2NY, UK., Welbeck KA; Biopharm Discovery, GlaxoSmithKline, Gunnels Wood Road, Stevenage SG1 2NY, UK., Harris CL; Immunology Research Unit, GlaxoSmithKline, Gunnels Wood Road, Stevenage SG1 2NY, UK., Feeney M; Immunology Research Unit, GlaxoSmithKline, Gunnels Wood Road, Stevenage SG1 2NY, UK., Hughes JP; Immunology Research Unit, GlaxoSmithKline, Gunnels Wood Road, Stevenage SG1 2NY, UK., Sepp A; Systems Modelling and Translational Biology, GlaxoSmithKline, Gunnels Wood Road, Stevenage SG1 2NY, UK., Batuwangala TD; Biopharm Discovery, GlaxoSmithKline, Gunnels Wood Road, Stevenage SG1 2NY, UK., Kitchen SJ; Immunology Research Unit, GlaxoSmithKline, Gunnels Wood Road, Stevenage SG1 2NY, UK., Nichols EM; Immunology Research Unit, GlaxoSmithKline, Gunnels Wood Road, Stevenage SG1 2NY, UK.

Publikováno v: Antibodies (Basel, Switzerland) [Antibodies (Basel)] 2021 Oct 12; Vol. 10 (4). Date of Electronic Publication: 2021 Oct 12.