Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Weizhun Yang"'
Autor:
Zibin Tan, Weizhun Yang, Nicholas A. O’Brien, Xingling Pan, Sherif Ramadan, Terence Marsh, Neal Hammer, Colette Cywes-Bentley, Mariana Vinacur, Gerald B. Pier, Jeffrey C. Gildersleeve, Xuefei Huang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Poly-β-(1–6)-N-acetylglucosamine (PNAG) is an important vaccine target, expressed on many pathogens. A critical hurdle in developing PNAG based vaccine is that the impacts of the number and the position of free amine vs N-acetylation on i
Externí odkaz:
https://doaj.org/article/3bb1198e173a4bd293f55ac76b647033
Autor:
Sherif Ramadan, Tianlu Li, Weizhun Yang, Jicheng Zhang, Zahra Rashidijahanabad, Zibin Tan, Narayanan Parameswaran, Xuefei Huang
Publikováno v:
ACS Central Science, Vol 6, Iss 6, Pp 913-920 (2020)
Externí odkaz:
https://doaj.org/article/3f65fd4e972d48f7b805a0299dc4dc64
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 13, Iss 1, Pp 2094-2114 (2017)
Most glycosylation reactions are performed by mixing the glycosyl donor and acceptor together followed by the addition of a promoter. While many oligosaccharides have been synthesized successfully using this premixed strategy, extensive protective gr
Externí odkaz:
https://doaj.org/article/c6034e302e9b47899a535150b55dcdad
Publikováno v:
Natural Product Reports; Sep2024, Vol. 41 Issue 9, p1403-1440, 38p
Autor:
Zibin Tan, Canchai Yang, Po-han Lin, Sherif Ramadan, Weizhun Yang, Zahra Rashidijahanabad, Shuyao Lang, Fatemeh Shafieichaharberoud, Jia Gao, Nachy Soloff, Xuanjun Wu, Steven Bolin, Dohun Pyeon, Xuefei Huang
More than two years into the global pandemic, SARS-CoV-2 remains a significant threat to public health. Immunities acquired from infection or current vaccines fail to provide long term protection against subsequent infections, mainly due to their fas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07944f67e6bf0b38331de8cda7f67e5f
https://doi.org/10.26434/chemrxiv-2022-rdk8m
https://doi.org/10.26434/chemrxiv-2022-rdk8m
Autor:
Jicheng Zhang, Li Liang, Weizhun Yang, Sherif Ramadan, Kedar Baryal, Chang‐Xin Huo, Jamie J. Bernard, Jian Liu, Linda Hsieh‐Wilson, Fuming Zhang, Robert J. Linhardt, Xuefei Huang
Publikováno v:
Angewandte Chemie (International ed. in English). 61(48)
Heparan sulfate (HS) plays important roles in many biological processes. The inherent complexity of naturally existing HS has severely hindered the thorough understanding of their structure-activity relationship. To facilitate biological studies, a n
Autor:
J. Sebastian Temme, Jennifer A. Crainic, Laura M. Walker, Weizhun Yang, Zibin Tan, Xuefei Huang, Jeffrey C. Gildersleeve
Publikováno v:
The Journal of biological chemistry. 298(10)
The immune system produces a diverse collection of antiglycan antibodies that are critical for host defense. At present, however, we know very little about the binding properties, origins, and sequences of these antibodies because of a lack of access
Publikováno v:
Organic Letters. 22:6429-6433
A successful synthesis of O-sulfated syndecan-1-like (Q23-E120) glyco-polypeptide was accomplished. The synthesis features the integration of an O-sulfated carbohydrate-bearing glycopeptide cassette with efficient protein ligation strategies, overcom
Autor:
Angela K. Wilson, Xuefei Huang, Yigitcan Eken, Weizhun Yang, Sherif Ramadan, Jicheng Zhang, Jian Liu, Logan Emerson Cole, Zeren Zhang, Yongmei Xu
Publikováno v:
Chemical Science
Proteoglycans are a family of complex glycoproteins with glycosaminoglycan chains such as heparan sulfate (HS) attached to the core protein backbone. Due to the high structural heterogeneity of HS in nature, it is challenging to decipher the respecti
Autor:
Zeren Zhang, Logan Cole, Yigitcan Eken, Jicheng Zhang, Jia Gao, Xuefei Huang, Angela Wilson, Jian Liu, Yongmei Xu, Sherif Ramadan, Weizhun Yang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::961b5b6d95143a37a9d32bca26f14ab8
https://doi.org/10.1021/scimeetings.0c07104
https://doi.org/10.1021/scimeetings.0c07104