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pro vyhledávání: '"Weiyu Bai"'
Autor:
Weiyu Bai
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103158- (2024)
Summary: Drug resistance is currently the biggest challenge in cancer chemotherapy. Here, we present a protocol to develop a chemotherapy drug screening process by constructing a cancer prognostic model (PM) using public databases. We describe steps
Externí odkaz:
https://doaj.org/article/9c56acd7588b4a2cb567aa05533d6314
Autor:
Weiyu Bai
Publikováno v:
STAR Protocols, Vol 5, Iss 2, Pp 103065- (2024)
Summary: Malignant tumor cells are typically more active in terms of metabolism and signal transduction compared to immune and normal cells. Here, we present a protocol to evaluate immune levels, abnormal metabolism, and signaling pathways in tumor t
Externí odkaz:
https://doaj.org/article/584803831245491c9a40b6e56cca1419
Autor:
Weiyu Bai
Publikováno v:
Heliyon, Vol 9, Iss 12, Pp e22885- (2023)
Background: Hepatocellular carcinoma (HCC) being a complex disease, commonly exhibits multifaceted presentations, rendering its treatment challenging and necessitating specific approaches. The tumor immune microenvironment is crucial in cancer treatm
Externí odkaz:
https://doaj.org/article/175e7412ad98467a884d9baf04204157
Publikováno v:
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-11 (2022)
Abstract Background Nuclear hormone receptors are involved in transcriptional regulation and many important cellular processes including development and metabolism. However, its role in DNA damage-induced apoptosis remains elusive. Methods Synchroniz
Externí odkaz:
https://doaj.org/article/05837d2674e34b0883df553b9b2be740
Publikováno v:
Cancer Biology & Medicine, Vol 19, Iss 8, Pp 1211-1223 (2022)
Objective: The BRAF inhibitor, vemurafenib, has been widely used in the treatment of patients with melanoma-bearing BRAFV600E mutations. While the initial response to vemurafenib is usually excellent, the majority of patients eventually develop resis
Externí odkaz:
https://doaj.org/article/a4c7194c32844833b7fac0b3b5911027
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Hepatocyte Nuclear Factor 4 Alpha (HNF4α) is a master transcription factor mainly expressed in the liver, kidney, intestine and endocrine pancreas. It regulates multiple target genes involved in embryonic development and metabolism. HNF4α-related d
Externí odkaz:
https://doaj.org/article/26a4b6602d304a42af0d2f54109fc318
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Overexpression of DGUOK promotes mitochondria oxidative phosphorylation and lung adenocarcinoma progression. However, the role and mechanism of DGUOK in regulation of mitochondria function and lung cancer progression still poorly understood. Here we
Externí odkaz:
https://doaj.org/article/6cb7d1428b9948d3b45f063007b34f78
Publikováno v:
Cancer Biology & Medicine. 19:1211-1223
OBJECTIVE The BRAF inhibitor, vemurafenib, has been widely used in the treatment of patients with melanoma-bearing BRAFV600E mutations. While the initial response to vemurafenib is usually excellent, the majority of patients eventually develop resist
Autor:
Weiyu Bai
Breast cancer is the most common and ranks the second cause of related cancer-related death in women. However, the relationship between inflammation-related gene signatures and the prognosis of breast cancer remains elusive. We constructed inflammati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::155074e23e44688cdaca443ad840ca45
https://doi.org/10.21203/rs.3.rs-2395472/v1
https://doi.org/10.21203/rs.3.rs-2395472/v1