Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Weiyang Tao"'
Autor:
Guozheng Li, Xin Ma, Shiyao Sui, Yihai Chen, Hui Li, Lei Liu, Xin Zhang, Lei Zhang, Yi Hao, Zihan Yang, Shuai Yang, Xu He, Qin Wang, Weiyang Tao, Shouping Xu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-19 (2024)
Abstract Background N4-Acetylcytidine (ac4C), a highly conserved post-transcriptional mechanism, plays a pivotal role in RNA modification and tumor progression. However, the molecular mechanism by which ac4C modification mediates tumor immunosuppress
Externí odkaz:
https://doaj.org/article/c1a25e44cbe048c6b87831ae7b8ce92c
Publikováno v:
World Journal of Surgical Oncology, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background The novel anti-HER2 antibody drug conjugates (ADCs) can effectively improve the long-term survival of patients with HER2-low expression breast cancer. However, pathological responses to neoadjuvant therapy (NAT) within HER2-low ex
Externí odkaz:
https://doaj.org/article/c2b07423e5df479a9abb6a50ba6a33a5
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
High-dimensional cell phenotyping is a powerful tool to study molecular and cellular changes in health and diseases. CyTOF enables high-dimensional cell phenotyping using tens of surface and intra-cellular markers. To utilize the full potential of Cy
Externí odkaz:
https://doaj.org/article/7c3c4599ee1145268397e26705c96a8d
Publikováno v:
Heliyon, Vol 10, Iss 6, Pp e27531- (2024)
Tyrosine kinase inhibitors (TKIs) have become first-line drugs for cancer treatment. However, their clinical use is seriously hindered since many patients experience diarrhea after receiving TKIs. The mechanisms of TKI-associated diarrhea remain uncl
Externí odkaz:
https://doaj.org/article/7fba04c5f007468ba108dd6bcdf19b7b
Publikováno v:
World Journal of Surgical Oncology, Vol 21, Iss 1, Pp 1-10 (2023)
Abstract Introduction Breast angiosarcoma is a rare malignancy of endovascular origin, accounting for less than 1% of all mammary cancers. Our aim was to explore clinicopathological features and the factors associated with prognosis. Methods We extra
Externí odkaz:
https://doaj.org/article/0671a28a781047049da3c7a5ce4a88c0
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
Weiyang Tao et al. describe RegEnrich, an R package capable of conducting several analyses to identify transcriptional regulators driving gene expression signatures. As an example, they apply RegEnrich to dozens of in vitro gene expression datasets t
Externí odkaz:
https://doaj.org/article/3d672839f2c749fd9990668e1ff0a5a1
Autor:
Jingwen Deng, Emmerik Leijten, Michel Olde Nordkamp, Guangjuan Zheng, Juliëtte Pouw, Weiyang Tao, Sarita Hartgring, Deepak Balak, Rianne Rijken, Runyue Huang, Timothy Radstake, Chuanjian Lu, Aridaman Pandit
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 12, Pp n/a-n/a (2022)
Abstract Objectives The precise pathogenesis of psoriasis remains incompletely explored. We aimed to better understand the underlying mechanisms of psoriasis, using a systems biology approach based on transcriptomics and microbiome profiling. Methods
Externí odkaz:
https://doaj.org/article/753ad63c033b4965947ca085ba60f963
Autor:
Gerdien Mijnheer, Lisanne Lutter, Michal Mokry, Marlot van der Wal, Rianne Scholman, Veerle Fleskens, Aridaman Pandit, Weiyang Tao, Mark Wekking, Stephin Vervoort, Ceri Roberts, Alessandra Petrelli, Janneke G. C. Peeters, Marthe Knijff, Sytze de Roock, Sebastiaan Vastert, Leonie S. Taams, Jorg van Loosdregt, Femke van Wijk
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
T regulatory (Treg) cells can differentiate into effector Treg (eTreg) cells that might be functional in inflammatory diseases. Using RNA sequencing and epigenetic profiling, the authors show that eTreg signatures in juvenile idiopathic arthritis joi
Externí odkaz:
https://doaj.org/article/0a5628b633d646d0b5877f5920381df7
Autor:
Sandra C. Silva-Cardoso, Weiyang Tao, Chiara Angiolilli, Ana P. Lopes, Cornelis P. J. Bekker, Abhinandan Devaprasad, Barbara Giovannone, Jaap van Laar, Marta Cossu, Wioleta Marut, Erik Hack, Rob J. de Boer, Marianne Boes, Timothy R. D. J. Radstake, Aridaman Pandit
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Fibrosis is a condition shared by numerous inflammatory diseases. Our incomplete understanding of the molecular mechanisms underlying fibrosis has severely hampered effective drug development. CXCL4 is associated with the onset and extent of fibrosis
Externí odkaz:
https://doaj.org/article/e286df9b07224ea08dc328f58bd71e1b
Autor:
Ceri A. Roberts, Femke van Wijk, Veerle Fleskens, Sytze de Roock, Mark Wekking, Sebastiaan J. Vastert, Marthe Knijff, Gerdien Mijnheer, Weiyang Tao, Janneke G. C. Peeters, Leonie S. Taams, Lisanne Lutter, Michal Mokry, Rianne C. Scholman, Marlot van der Wal, Jorg van Loosdregt, Stephin J. Vervoort, Aridaman Pandit, Alessandra Petrelli
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Treg cells are critical regulators of immune homeostasis, and environment-driven Treg cell differentiation into effector (e)Treg cells is crucial for optimal functioning. However, human Treg cell programming in inflammation is unclear. Here, we combi