Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Weiya Liu"'
Publikováno v:
Frontiers in Environmental Science, Vol 10 (2022)
Sustainable development is crucial to the survival and healthy development of enterprises, which is closely related to their financing situation. Supply chain finance is an effective way to improve and enhance the financing situation by easing financ
Externí odkaz:
https://doaj.org/article/1cc9e7fc0c8b42649a4671674eb04ce5
Publikováno v:
Buildings, Vol 12, Iss 11, p 1940 (2022)
Taking the frame-supported shear wall structure of a 102.1 m high metro depot as the test object, the structure has obvious vertical irregularity, and a quasi-static test was carried out on the structural model with the scale of 1/5. The damage devel
Externí odkaz:
https://doaj.org/article/b3f78f841c4d49d6ba8059b08ade8296
Autor:
Anuj Khandelwal, Caitlin N. Kent, Maurie Balch, Shuxia Peng, Sanket J. Mishra, Junpeng Deng, Victor W. Day, Weiya Liu, Chitra Subramanian, Mark Cohen, Jeffery M. Holzbeierlein, Robert Matts, Brian S. J. Blagg
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-7 (2018)
The molecular chaperone Hsp90 oversees the folding of many proteins associated with cancer progression but existing small-molecule inhibitors of this pathway are not isoform-selective. Here, the authors rationally design an Hsp90 inhibitor that displ
Externí odkaz:
https://doaj.org/article/22d6d57dbf0548efa5ef84106a4676a4
Autor:
Weiya Liu, Benjamin L Woolbright, Karim Pirani, Ryan Didde, Erika Abbott, Gaurav Kaushik, Paige Martin, Jill Hamilton-Reeves, John A Taylor, Jeffrey M Holzbeierlein, Shrikant Anant, Eugene K Lee
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218737 (2019)
PurposeBladder cancer is a "Warburg-like" tumor characterized by a reliance on aerobic glycolysis and expression of pyruvate kinase M2 (PKM2). PKM2 oscillates between an active tetramer and an inactive dimer. We aim to further characterize PKM2, in p
Externí odkaz:
https://doaj.org/article/8ff889ab6a87485e8cc417e642e9b833
Autor:
Zhilong Jiang, Weiya Liu, Jun Wang, Bangtang Chen, Zihao Wu, Fan Fu, Rui Miao, Ting Ouyang, Wenzhi Lv, Yongchao Huang, Die Liu, Zhao-Qing Liu, Mingzhao Chen, Pingshan Wang
Publikováno v:
Inorganic Chemistry.
Autor:
Zhilong Jiang, Zihao Wu, Jun Wang, Bangtang Chen, Min Wang, Weiya Liu, Wenzhi Lv, Rui Miao, He Zhao, Die Liu, Shenghua Chen, Mingzhao Chen, Pingshan Wang
Publikováno v:
Nano Research.
Autor:
Jun Wang, Zhilong Jiang, Weiya Liu, Zihao Wu, Rui Miao, Fan Fu, Jia‐Fu Yin, Bangtang Chen, Qiangqiang Dong, He Zhao, Kaixiu Li, Guotao Wang, Die Liu, Panchao Yin, Yiming Li, Mingzhao Chen, Pingshan Wang
Publikováno v:
Angewandte Chemie (International ed. in English). 62(1)
Fractal structures with self-similarity are of fundamental importance in the fields of aesthetic, chemistry and mathematics. Here, by taking advantage of constructs the rational geometry-directed precursor design, we report the construction of two fa
Autor:
Zhilong Jiang, He Zhao, Jun Wang, Bangtang Chen, Wenzhi Lv, Yiming Li, Qiangqiang Dong, Die Liu, Weiya Liu, Min Wang, Fan Fu, Seok-Ho Hwang, Mingzhao Chen, Pingshan Wang
Publikováno v:
Chinese Chemical Letters. :108334
Autor:
Leonard M. Neckers, John Koren, Kristin Beebe, Vitumbiko Munthali, Jeffrey M. Holzbeierlein, Brian S. J. Blagg, Weiya Liu, Sanket J. Mishra, John A. Taylor, Monimoy Banerjee, Caitlin N. Kent
Publikováno v:
Journal of Medicinal Chemistry. 64:1545-1557
The 90 kD heat shock proteins (Hsp90) are molecular chaperones that are responsible for the folding of select proteins, many of which are directly associated with cancer progression. Consequently, inhibition of the Hsp90 protein folding machinery res
Publikováno v:
2021 7th International Conference on Mechanical Engineering and Automation Science (ICMEAS).