Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Weixin Tao"'
Autor:
Liyuan Kong, Gudan Xu, Xiaoqin Liu, Jingwen Wang, Zenglin Tang, You-Sheng Cai, Kun Shen, Weixin Tao, Yu Zheng, Zixin Deng, Neil P.J. Price, Wenqing Chen
Publikováno v:
iScience, Vol 22, Iss , Pp 430-440 (2019)
Summary: Minimycin (MIN) is a C-nucleoside antibiotic structurally related to pseudouridine, and indigoidine is a naturally occurring blue pigment produced by diverse bacteria. Although MIN and indigoidine have been known for decades, the logic under
Externí odkaz:
https://doaj.org/article/464197e4a7954be3b7f3ed4145ef57cf
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Microbial natural products (NPs) especially of the Streptomyces genus have been regarded as an unparalleled resource for pharmaceutical drugs discovery. Moreover, recent progress in sequencing technologies and computational resources further reinforc
Externí odkaz:
https://doaj.org/article/5652bd5060314b9a9c44b5365f8451ed
Publikováno v:
mBio, Vol 6, Iss 6 (2015)
ABSTRACT The clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein 9 (Cas9) system, an RNA-guided nuclease for specific genome editing in vivo, has been adopted in a wide variety of organisms. In contrast, the in
Externí odkaz:
https://doaj.org/article/1eed16433b004c86b10ac002d91cf649
Autor:
Weixin Tao, Neil P. J. Price, Liyuan Kong, Xiaoqin Liu, Kun Shen, Tang Zenglin, Gudan Xu, Yu Zheng, You-Sheng Cai, Zixin Deng, Wenqing Chen, Jingwen Wang
Publikováno v:
iScience, Vol 22, Iss, Pp 430-440 (2019)
iScience
iScience
Summary Minimycin (MIN) is a C-nucleoside antibiotic structurally related to pseudouridine, and indigoidine is a naturally occurring blue pigment produced by diverse bacteria. Although MIN and indigoidine have been known for decades, the logic underl
Publikováno v:
ACS Synthetic Biology. 8:1991-1997
Direct cloning of natural product pathways for efficient refactoring and heterologous expression has become an important strategy for microbial natural product research and discovery, especially for those kept silent or poorly expressed in the origin
Autor:
Peter F. Leadlay, Sophia Harringer, Judith Havemann, Robert Jenkins, Weixin Tao, Shishi Wen, Yuhui Sun, Manuela Tosin, Marie E. Yurkovich
Publikováno v:
Chemical Communications. 53:1912-1915
Chemical 'chain termination' probes were utilised for the investigation of thiotetronate antibiotic biosynthesis in the filamentous bacteria Lentzea sp. and Streptomyces thiolactonus NRRL 15439. The use of these tools led to the capture of biosynthet
Autor:
Hyoung Ju Lee, Eunsook Chung, Eun Joo Jung, Weixin Tao, Hyun Gi Kong, Soo Yeon Choi, Seon-Woo Lee, Jing Wu
Publikováno v:
Physiological and Molecular Plant Pathology. 90:57-64
Metabolism in Ralstonia solanacearum , which causes lethal wilt on Solanaceous plants, is poorly understood. In this study, we selected a Tn5-inserted mutant of R. solanacearum SL341 showing various phenotypic changes and altered virulence. When the
Autor:
Jae Wook Lee, Seung Yeup Lee, Raees Khan, Eul Chul Hwang, Myung Hwan Lee, Weixin Tao, Kihyuck Choi, Seon-Woo Lee
Publikováno v:
Journal of biotechnology. 270
Autoinducers are indispensable for bacterial cell–cell communication. However, due to the reliance on culture-based techniques, few autoinducer-hydrolyzing enzymes are known. In this study, we characterized soil metagenome-derived unique enzymes ca
Autor:
Zixin Deng, Xu Chen, Jian Yang, Jie Wu, Wei Xu, Yuanzhen Liu, Yuhui Sun, Zhengyuan Li, Weixin Tao
Publikováno v:
ACS chemical biology. 12(10)
The streptovaricins, chemically related to the rifamycins, are highly effective antibacterial agents, particularly against mycobacteria. Herein, a bioassay-guided investigation of Streptomyces spectabilis CCTCC M2017417 has led to the characterizatio
Publikováno v:
Science China Chemistry. 56:1364-1371
Tetronate antibiotics, a growing family of natural products featuring a characteristic tetronic acid moiety, are of importance and of particular interest for their typical structures, especially the spirotetronate structure, and corresponding versati