Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Weiwei Mu"'
Autor:
Jinhu Liu, Huajun Zhao, Tong Gao, Xinyan Huang, Shujun Liu, Meichen Liu, Weiwei Mu, Shuang Liang, Shunli Fu, Shijun Yuan, Qinglin Yang, Panpan Gu, Nan Li, Qingping Ma, Jie Liu, Xinke Zhang, Na Zhang, Yongjun Liu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Cytotherapy is a strategy to deliver modified cells to a diseased tissue, but targeting solid tumours remains challenging. Here we design macrophages, harbouring a surface glypican-3-targeting peptide and carrying a cargo to combat solid tum
Externí odkaz:
https://doaj.org/article/e0f6524a4aa747788c8e0d90890f216b
Autor:
Huizhen Yang, Weiwei Mu, Shijun Yuan, Han Yang, Lili Chang, Xiao Sang, Tong Gao, Shuang Liang, Xiaoqing Liu, Shunli Fu, Zipeng Zhang, Yongjun Liu, Na Zhang
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Immune checkpoint inhibitors (ICIs) combined with antiangiogenic therapy have shown encouraging clinical benefits for the treatment of unresectable or metastatic hepatocellular carcinoma (HCC). Nevertheless, therapeutic efficacy and wide cli
Externí odkaz:
https://doaj.org/article/42ed710dee35490caf73fdc1ad5e65a0
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Protein methylation, similar to DNA methylation, primarily involves post-translational modification (PTM) targeting residues of nitrogen-containing side-chains and other residues. Protein arginine methylation, occurred on arginine residue, is mainly
Externí odkaz:
https://doaj.org/article/bd82a1001f3743bebe09413ae56e5d27
Nano‐Regulator Inhibits Tumor Immune Escape via the 'Two‐Way Regulation' Epigenetic Therapy Strategy
Autor:
Shuang Liang, Meichen Liu, Weiwei Mu, Tong Gao, Shuying Gao, Shunli Fu, Shijun Yuan, Jinhu Liu, Yongjun Liu, Dandan Jiang, Na Zhang
Publikováno v:
Advanced Science, Vol 11, Iss 9, Pp n/a-n/a (2024)
Abstract Tumor immune escape caused by low levels of tumor immunogenicity and immune checkpoint‐dependent suppression limits the immunotherapeutic effect. Herein, a “two‐way regulation” epigenetic therapeutic strategy is proposed using a nove
Externí odkaz:
https://doaj.org/article/9e2c282fed074761a5f80200edac5908
Publikováno v:
Journal of Business Economics and Management, Vol 24, Iss 6 (2023)
The effect of FinTech on income inequality in China and the characteristics of the existing thresholds are examined in this study based on China provincial panel data from 2011 to 2020 by combining dynamic panel differential GMM with panel threshold
Externí odkaz:
https://doaj.org/article/4252bb44d4e342a8ae602a17a12f8163
Autor:
Shunli Fu, Lili Chang, Shujun Liu, Tong Gao, Xiao Sang, Zipeng Zhang, Weiwei Mu, Xiaoqing Liu, Shuang Liang, Han Yang, Huizhen Yang, Qingping Ma, Yongjun Liu, Na Zhang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Targeting tumour immunosuppressive microenvironment is a crucial strategy in immunotherapy. However, the critical role of the tumour lymph node (LN) immune microenvironment (TLIME) in the tumour immune homoeostasis is often ignored. Here, we
Externí odkaz:
https://doaj.org/article/088ad66e83394e9da269425f4225324a
Publikováno v:
Pharmaceutics, Vol 15, Iss 12, p 2770 (2023)
Nano-delivery systems have demonstrated great promise in the therapy of cancer. However, the therapeutic efficacy of conventional nanomedicines is hindered by the clearance of the blood circulation system and the physiological barriers surrounding th
Externí odkaz:
https://doaj.org/article/13fa9f9f76e046fc950badc6dafc81d7
Autor:
Leiqiang Han, Shuang Liang, Weiwei Mu, Zipeng Zhang, Limin Wang, Shumin Ouyang, Bufan Yao, Yongjun Liu, Na Zhang
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 17, Iss 1, Pp 129-138 (2022)
Nanomedicine has made great progress in the targeted therapy of cancer. Here, we established a novel drug-mate strategy by studying the formulation of nanodrugs at the molecular level. In the drug-mate combination, the drug is a hydrophobic drug that
Externí odkaz:
https://doaj.org/article/8fe42d77969f4d439a40fee20438d143
Autor:
Weiwei Mu, Qihui Chu, Huizhen Yang, Li Guan, Shunli Fu, Tong Gao, Xiao Sang, Zipeng Zhang, Shuang Liang, Yongjun Liu, Na Zhang
Publikováno v:
Advanced Science, Vol 9, Iss 9, Pp n/a-n/a (2022)
Abstract Eliminating primary tumor (“roots”) and inhibiting associated‐circulating tumor cells (associated‐CTCs, “seeds”) are vital issues that need to be urgently addressed in cancer therapy. Associated‐CTCs, which include single CTCs,
Externí odkaz:
https://doaj.org/article/586454de3c53460ea06f7099fc5d14fb
Autor:
Teng Hou, Tianqi Wang, Weiwei Mu, Rui Yang, Shuang Liang, Zipeng Zhang, Shunli Fu, Tong Gao, Yongjun Liu, Na Zhang
Publikováno v:
Nano-Micro Letters, Vol 13, Iss 1, Pp 1-20 (2020)
Abstract Cell therapy is a promising strategy for cancer therapy. However, its therapeutic efficiency remains limited due to the complex and immunosuppressive nature of tumor microenvironments. In this study, the “cell-chemotherapy” strategy was
Externí odkaz:
https://doaj.org/article/21434d758ae64e6b89945b975693561c