Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Weiwei Ge"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Gynostemma pentaphyllum (Thunb.) Makino (G. pentaphyllum) is a medicinal and edible plant with multiple functions of liver protection, anti-tumor, anti-inflammation, balancing blood sugar and blood lipids. The nutritional value of the G. pen
Externí odkaz:
https://doaj.org/article/a0034011e80b4f058f55559072a04044
Autor:
Pan Pan, Weiwei Ge, Zhiwei Lei, Wei luo, Yuqing Liu, Zhanwen Guan, Lumiao Chen, Zhenyang Yu, Miaomiao Shen, Dingwen Hu, Qi Xiang, Wenbiao Wang, Pin Wan, Mingfu Tian, Yang Yu, Zhen Luo, Xulin Chen, Heng Xiao, Qiwei Zhang, Xujing Liang, Xin Chen, Yongkui Li, Jianguo Wu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-15 (2023)
Abstract Viral infection in respiratory tract usually leads to cell death, impairing respiratory function to cause severe disease. However, the diversity of clinical manifestations of SARS-CoV-2 infection increases the complexity and difficulty of vi
Externí odkaz:
https://doaj.org/article/843dd46511054fb3a9a8309d84408f93
Autor:
Jing Xu, Guanghui Zheng, Juntao Hu, Weiwei Ge, Jennifer L. Bradley, Joseph P. Ornato, Wanchun Tang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 156, Iss , Pp 113847- (2022)
Post-resuscitation cerebral ischemia-reperfusion injury (IRI) is a vital contributor to poor neurological prognosis. Exploring novel therapeutics that attenuate cerebral IRI is of great significance. Inflammation plays a role in the development of ce
Externí odkaz:
https://doaj.org/article/17e1909e8165491db261c7204dbe7c59
Autor:
Pan Pan, Miaomiao Shen, Zhenyang Yu, Weiwei Ge, Keli Chen, Mingfu Tian, Feng Xiao, Zhenwei Wang, Jun Wang, Yaling Jia, Wenbiao Wang, Pin Wan, Jing Zhang, Weijie Chen, Zhiwei Lei, Xin Chen, Zhen Luo, Qiwei Zhang, Meng Xu, Geng Li, Yongkui Li, Jianguo Wu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
SARS-CoV-2 infection has been shown to drive NLRP3 inflammasome activation and thereby cytokine storm, but how it does so is unclear. Here the authors show that the viral N protein can bind to NLRP3, resulting in enhanced interaction with ASC and the
Externí odkaz:
https://doaj.org/article/40b9476cf93f4264a3303d60ead8698b
Autor:
Changsheng Wang, Evelyne Bischof, Jing Xu, Qinyue Guo, Guanghui Zheng, Weiwei Ge, Juntao Hu, Elena Laura Georgescu Margarint, Jennifer L. Bradley, Mary Ann Peberdy, Joseph P. Ornato, Changqing Zhu, Wanchun Tang
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundPrevious studies have demonstrated that inflammation and impaired microcirculation are key factors in post-resuscitation syndromes. Here, we investigated whether methylprednisolone (MP) could improve myocardial function and microcirculation
Externí odkaz:
https://doaj.org/article/532ebb3322cc43b093c284e56d114373
Autor:
Guanghui Zheng, Jing Xu, Fenglian He, Juntao Hu, Weiwei Ge, Xianfei Ji, Changsheng Wang, Jennifer L. Bradley, Mary Ann Peberdy, Joseph P. Ornato, Stefano Toldo, Tong Wang, Wanchun Tang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 143, Iss , Pp 112093- (2021)
Cardiac arrest (CA) remains a major public health issue. Inflammatory responses with overproduction of interleukin-1β regulated by NLRP3 inflammasome activation play a crucial role in cerebral ischemia/reperfusion injury. We investigated the effects
Externí odkaz:
https://doaj.org/article/80c6f4fb5e3b4e75ba160f9f4c5ff4ad
Autor:
Xianfei Ji, Jennifer L. Bradley, Guanghui Zheng, Weiwei Ge, Jing Xu, Juntao Hu, Fenglian He, Rabiya Shabnam, Mary Ann Peberdy, Joseph P. Ornato, Qun Chen, Edward J. Lesnefsky, Wanchun Tang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 140, Iss , Pp 111743- (2021)
Brain mitochondria are more sensitive to global ischemia compared to heart mitochondria. Complex I in the electron transport chain (ETC) is sensitive to ischemic injury and is a major control point of the rate of ADP stimulated oxygen consumption. Th
Externí odkaz:
https://doaj.org/article/82cb046d56e94fe9a93c5f74b08e924a
Autor:
Pan Pan, Geng Li, Miaomiao Shen, Zhenyang Yu, Weiwei Ge, Zizhao Lao, Yaohua Fan, Keli Chen, Zhihao Ding, Wenbiao Wang, Pin Wan, Muhammad Adnan Shereen, Zhen Luo, Xulin Chen, Qiwei Zhang, Luping Lin, Jianguo Wu
Publikováno v:
PLoS Pathogens, Vol 17, Iss 7, p e1008603 (2021)
Dengue virus (DENV) is a mosquito-borne pathogen that causes a spectrum of diseases including life-threatening dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). Vascular leakage is a common clinical crisis in DHF/DSS patients and highly
Externí odkaz:
https://doaj.org/article/45c4069d75224579952be44e4ed696bc
Autor:
Weiwei Ge, Qiaohua Hu, Xiangshao Fang, Juanhua Liu, Jing Xu, Juntao Hu, Xuefen Liu, Qin Ling, Yue Wang, He Li, Ming Gao, Longyuan Jiang, Zhengfei Yang, Wanchun Tang
Publikováno v:
Journal of Inflammation, Vol 16, Iss 1, Pp 1-10 (2019)
Abstract Background Sepsis is a systemic inflammatory response syndrome caused by severe infections. LDK378, a second-generation ALK inhibitor, exhibits a potential anti-inflammatory function against sepsis. Micro- and macro-circulatory dysfunctions
Externí odkaz:
https://doaj.org/article/258f6f139845441d8ae49e5ed4d587fd
Publikováno v:
Technology in Cancer Research & Treatment, Vol 19 (2020)
Objective: Previous studies have shown that abnormal expression of microRNA-184 leads to a variety of cancers, including pancreatic ductal adenocarcinoma, suggesting microRNA-184 as a new treatment target for pancreatic ductal adenocarcinoma. However
Externí odkaz:
https://doaj.org/article/8ef9b2b8db0b41f78efe337f83fba1b9