Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Weiwang Gu"'
Autor:
Hailong Su, Jun Liu, Jianhai Yu, Zhenzhen Qiu, Wenhan Liang, Wangsheng Wu, Haifeng Mo, Hongwei Li, Wei Zhao, Weiwang Gu
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 11, p e0011770 (2023)
Zika virus can infect the fetus through the placental barrier, causing ZIKV congenital syndrome and even miscarriage, which can cause great harm to pregnant women and infants. Currently, there is no vaccine and drug available to combat the Zika virus
Externí odkaz:
https://doaj.org/article/73aac49d30844cafbf5861ef1605a13b
Autor:
Peng Gu, Qin Yang, Bangzhu Chen, Ya-nan Bie, Wen Liu, Yuguang Tian, Hongquan Luo, Tao Xu, Chunjin Liang, Xing Ye, Yan Liu, Xiangwu Tang, Weiwang Gu
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 21, Iss , Pp 530-547 (2021)
Hereditary tyrosinemia type I (HT1) results from the loss of fumarylacetoacetate hydrolase (FAH) activity and can lead to lethal liver injury (LLI). Therapeutic options for HT1 remain limited. The FAH−/− pig, a well-characterized animal model of
Externí odkaz:
https://doaj.org/article/5d4f198e629e4baf9845e304c5d778a9
Autor:
Jinrong Huang, Lin Lin, Zhanying Dong, Ling Yang, Tianyu Zheng, Weiwang Gu, Yan Zhang, Tailang Yin, Evelina Sjöstedt, Jan Mulder, Mathias Uhlén, Karsten Kristiansen, Lars Bolund, Yonglun Luo
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Huang et al performed a genome-wide RNA editing investigation in the porcine brain in which they found over 680,000 A-to-I RNA editing sites. They identified conserved recoding events between pig and human brains thus providing an extensive resource
Externí odkaz:
https://doaj.org/article/1b3fdee5bc7048e1883e607c49d37f5a
Autor:
BANGZHU CHEN, DONGSHU GU, HONGWEI ZHOU, MIN YUE, WEIWANG GU, XIA JIANG, XIAOHUA SU, ZUHUA RONG
Publikováno v:
Polish Journal of Microbiology, Vol 67, Iss 3 (2018)
In this study, the gut microbiota was characterized in four age strata of Tibetan minipigs. Results indicated that the fecal bacteria of 7-, 28-, 56-, and 180-day-old minipigs did not significantly differ in terms of phylogenetic diversity (i.e., PD
Externí odkaz:
https://doaj.org/article/5e5bc7086bad4321a868d68724fd912b
Autor:
Tang Hai, Chunwei Cao, Haitao Shang, Weiwei Guo, Yanshuang Mu, Shulin Yang, Ying Zhang, Qiantao Zheng, Tao Zhang, Xianlong Wang, Yu Liu, Qingran Kong, Kui Li, Dayu Wang, Meng Qi, Qianlong Hong, Rui Zhang, Xiupeng Wang, Qitao Jia, Xiao Wang, Guosong Qin, Yongshun Li, Ailing Luo, Weiwu Jin, Jing Yao, Jiaojiao Huang, Hongyong Zhang, Menghua Li, Xiangmo Xie, Xuejuan Zheng, Kenan Guo, Qinghua Wang, Shibin Zhang, Liang Li, Fei Xie, Yu Zhang, Xiaogang Weng, Zhi Yin, Kui Hu, Yimei Cong, Peng Zheng, Hailong Zou, Leilei Xin, Jihan Xia, Jinxue Ruan, Hegang Li, Weiming Zhao, Jing Yuan, Zizhan Liu, Weiwang Gu, Ming Li, Yong Wang, Hongmei Wang, Shiming Yang, Zhonghua Liu, Hong Wei, Jianguo Zhao, Qi Zhou, Anming Meng
Publikováno v:
eLife, Vol 6 (2017)
N-ethyl-N-nitrosourea (ENU) mutagenesis is a powerful tool to generate mutants on a large scale efficiently, and to discover genes with novel functions at the whole-genome level in Caenorhabditis elegans, flies, zebrafish and mice, but it has never b
Externí odkaz:
https://doaj.org/article/cf41846c1164446c96c69e5c95f2b662
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166560 (2016)
Heart failure(HF) is a dangerous disease that affects millions of patients. Radix Salvia is widely used in Chinese clinics to treat heart diseases. Salvianolic acid B(SalB) is the major active component of Radix Salvia. This study investigated the me
Externí odkaz:
https://doaj.org/article/fe320aa666894eb8be64279f4a8163dc
Autor:
Yinan Wang, Chuanhe Yang, Qingqing Gu, Michelle Sims, Weiwang Gu, Lawrence M Pfeffer, Junming Yue
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130341 (2015)
The transcription factor Krüppel-like factor 4 (KLF4) has been implicated in regulating cell proliferation, migration and differentiation in a variety of human cells and is one of four factors required for the induction of pluripotent stem cell repr
Externí odkaz:
https://doaj.org/article/eb71a6833302487e8183713c7111ee91
Autor:
Zixuan Chen, Yinan Wang, Wen Liu, Guannan Zhao, Suechin Lee, Andrea Balogh, Yanan Zou, Yuqi Guo, Zhan Zhang, Weiwang Gu, Chengyao Li, Gabor Tigyi, Junming Yue
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105331 (2014)
Ovarian cancer presents therapeutic challenges due to its typically late detection, aggressive metastasis, and therapeutic resistance. The transcription factor Krüppel-like factor 4 (KLF4) has been implicated in human cancers as a tumor suppressor o
Externí odkaz:
https://doaj.org/article/410810750d3d4c0f8ea4dc0f7f06f925
Autor:
Quanmei Yan, Huaqiang Yang, Dongshan Yang, Bentian Zhao, Zhen Ouyang, Zhaoming Liu, Nana Fan, Hongsheng Ouyang, Weiwang Gu, Liangxue Lai
Publikováno v:
Cell Regeneration, Vol 3, Iss 1 (2014)
The myxovirus resistance gene (Mx1) has a broad spectrum of antiviral activities. It is therefore an interesting candidate gene to improve disease resistance in farm animals. In this study, we report the use of somatic cell nuclear transfer (SCNT) to
Externí odkaz:
https://doaj.org/article/1918c9c3ef4247f2ba6c4b74bf1b45f8
Autor:
Nana Pei, Feilong Jie, Jie Luo, Renqiang Wan, Yanling Zhang, Xinglu Chen, Zhibing Liang, Hongyan Du, Andrew Li, Baihong Chen, Yi Zhang, Colin Sumners, Jinlong Li, Weiwang Gu, Hongwei Li
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92253 (2014)
Increased expression of angiotensin II type 2 receptor (AT2R) induces apoptosis in numerous tumor cell lines, with either Angiotensin II-dependent or Angiotensin II-independent regulation, but its molecular mechanism remains poorly understood. Here,
Externí odkaz:
https://doaj.org/article/703bc65105b34bb79ef1e82291a5e02b