Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Weitao Que"'
Autor:
Weitao Que, Hisashi Ueta, Xin Hu, Miwa Morita-Nakagawa, Masayuki Fujino, Daisuke Ueda, Nobuko Tokuda, Wenxin Huang, Wen-Zhi Guo, Lin Zhong, Xiao-Kang Li
Publikováno v:
iScience, Vol 26, Iss 9, Pp 107691- (2023)
Summary: The liver has long been deemed a tolerogenic organ. We employed high-dimensional mass cytometry and immunohistochemistry to depict the temporal and spatial dynamics of immune cells in the spleen and liver in a murine model of spontaneous liv
Externí odkaz:
https://doaj.org/article/d0f85edbc0264675a40c61385981e964
CD93 overexpresses in liver hepatocellular carcinoma and represents a potential immunotherapy target
Autor:
Qianwei Jiang, Jing Kuai, Zhongyi Jiang, Weitao Que, Pusen Wang, Wenxin Huang, Wei Ding, Lin Zhong
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundLiver hepatocellular carcinoma (LIHC) is one of the malignant tumors with high incidence as well as high death, which is ranked as the sixth most common tumor and the third highest mortality worldwide. CD93, a transmembrane protein, has bee
Externí odkaz:
https://doaj.org/article/780bd7e5a1ea4034aaf6fd996a5409fa
Autor:
Zhongyi Jiang, Qianwei Jiang, Xu Fang, Pusen Wang, Weitao Que, Hao Li, Yang Yu, Xueni Liu, Chunguang Wang, Lin Zhong
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background Complement component(C7) gene has been shown to influence the prognosis in Hepatocellular carcinoma (HCC) patients. The association between C7 and HCC recurrence after orthotopic liver transplantation (OLT), however, is still unkn
Externí odkaz:
https://doaj.org/article/ab5d75a01835471bb55f4c8c59fd80ec
Publikováno v:
MedComm, Vol 3, Iss 2, Pp n/a-n/a (2022)
Abstract CD4+CD25+ regulatory T cells (Tregs), a subpopulation of naturally CD4+ T cells that characteristically express transcription factor Forkhead box P3 (FOXP3), play a pivotal role in the maintenance of immune homeostasis and the prevention of
Externí odkaz:
https://doaj.org/article/1146df7511fd45be8a32cf2ebbc8a82e
Autor:
Pusen Wang, Baojie Shi, Chunguang Wang, Yuanyuan Wang, Weitao Que, Zhongyi Jiang, Xueni Liu, Qianwei Jiang, Hao Li, Zhihai Peng, Lin Zhong
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 5, Pp n/a-n/a (2022)
Abstract Sepsis remains the most lethal infectious disease and substantially impairs patient prognosis after liver transplantation (LT). Our previous study reported a role of the pannexin 1 (PANX1)–interleukin‐33 (IL‐33) axis in activating inna
Externí odkaz:
https://doaj.org/article/f157fed08aca4e2082f78d3a25b7dbb6
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundOridonin (Ori), the main bioactive ingredient of the natural anti-inflammatory herb Rabdosia rubescens, could be a covalent inhibitor of the NLRP3 inflammasome. Solid organ transplantation provides a life-saving optional therapy for patient
Externí odkaz:
https://doaj.org/article/359018a9c4204169a862c9d7e0f7d062
Autor:
Keiichi Uto, Seisuke Sakamoto, Weitao Que, Keita Shimata, Shintaro Hashimoto, Masataka Sakisaka, Yasuko Narita, Daiki Yoshii, Lin Zhong, Yoshihiro Komohara, Xiao-Kang Li, Yukihiro Inomata, Taizo Hibi
Publikováno v:
BMC Gastroenterology, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background Liver transplantation (LT) is considered the standard treatment for end-stage liver disease, but ideal donors remain in limited supply, resulting in an unavoidable increase in the need to use grafts from marginal donors. The atten
Externí odkaz:
https://doaj.org/article/53732b65a70e45909fe95659b9248506
Autor:
Jing Zhao, Weitao Que, Xiaoxiao Du, Masayuki Fujino, Naotsugu Ichimaru, Hisashi Ueta, Nobuko Tokuda, Wen-zhi Guo, Piotr Zabrocki, Hans de Haard, Norio Nonomura, Xiao-Kang Li
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Allograft rejection has been an obstacle for the long-term survival of patients. CD70, a tumor necrosis factor (TNF) family member critically expressed on antigen-presenting cells and strongly but transiently up-regulated during lymphocyte activation
Externí odkaz:
https://doaj.org/article/ab0646756e1b4ea4a56fd8f7fdebea57
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Current organ transplantation therapy is life-saving but accompanied by well-recognized side effects due to post-transplantation systematic immunosuppressive treatment. Dendritic cells (DCs) are central instigators and regulators of transplantation i
Externí odkaz:
https://doaj.org/article/75df40f99a5f4b048195194c79e455f4
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Liver transplantation is the ideal treatment approach for a variety of end-stage liver diseases. However, life-long, systemic immunosuppressive treatment after transplantation is required to prevent rejection and graft loss, which is associated with
Externí odkaz:
https://doaj.org/article/527795575b184277ab5c92f67fad36ac