RNA Editing Signatures Powered by Artificial Intelligence: A New Frontier in Differentiating Schizophrenia, Bipolar, and Schizoaffective Disorders.

Autor: Checa-Robles FJ; ALCEDIAG, Parc Euromédecine, 34184 Montpellier Cedex 4, France.; Sys2Diag, UMR 9005 CNRS/ALCEN, Parc Euromédecine, 34184 Montpellier Cedex 4, France., Salvetat N; ALCEDIAG, Parc Euromédecine, 34184 Montpellier Cedex 4, France.; Sys2Diag, UMR 9005 CNRS/ALCEN, Parc Euromédecine, 34184 Montpellier Cedex 4, France., Cayzac C; ALCEDIAG, Parc Euromédecine, 34184 Montpellier Cedex 4, France.; Sys2Diag, UMR 9005 CNRS/ALCEN, Parc Euromédecine, 34184 Montpellier Cedex 4, France., Menhem M; ALCEDIAG, Parc Euromédecine, 34184 Montpellier Cedex 4, France.; Sys2Diag, UMR 9005 CNRS/ALCEN, Parc Euromédecine, 34184 Montpellier Cedex 4, France., Favier M; ALCEDIAG, Parc Euromédecine, 34184 Montpellier Cedex 4, France.; Sys2Diag, UMR 9005 CNRS/ALCEN, Parc Euromédecine, 34184 Montpellier Cedex 4, France., Vetter D; ALCEDIAG, Parc Euromédecine, 34184 Montpellier Cedex 4, France.; Sys2Diag, UMR 9005 CNRS/ALCEN, Parc Euromédecine, 34184 Montpellier Cedex 4, France., Ouna I; Sys2Diag, UMR 9005 CNRS/ALCEN, Parc Euromédecine, 34184 Montpellier Cedex 4, France., Nani JV; Department of Pharmacology, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo CEP 04044-20, Brazil.; National Institute for Translational Medicine (INCT-TM, CNPq/FAPESP/CAPES), Ribeirão Preto CEP 14040-900, Brazil., Hayashi MAF; Department of Pharmacology, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo CEP 04044-20, Brazil.; National Institute for Translational Medicine (INCT-TM, CNPq/FAPESP/CAPES), Ribeirão Preto CEP 14040-900, Brazil., Brietzke E; Department of Psychiatry, School of Medicine, Queen's University, Kingston, ON K7L 7X3, Canada., Weissmann D; ALCEDIAG, Parc Euromédecine, 34184 Montpellier Cedex 4, France.; Sys2Diag, UMR 9005 CNRS/ALCEN, Parc Euromédecine, 34184 Montpellier Cedex 4, France.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2024 Dec 03; Vol. 25 (23). Date of Electronic Publication: 2024 Dec 03.

AI algorithm combined with RNA editing-based blood biomarkers to discriminate bipolar from major depressive disorders in an external validation multicentric cohort.

Autor: Salvetat N; ALCEDIAG/Sys2Diag, CNRS UMR 9005, Parc Euromédecine, Montpellier, France., Checa-Robles FJ; ALCEDIAG/Sys2Diag, CNRS UMR 9005, Parc Euromédecine, Montpellier, France., Delacrétaz A; Les Toises. Center for psychiatry and psychotherapy, Lausanne, Switzerland., Cayzac C; ALCEDIAG/Sys2Diag, CNRS UMR 9005, Parc Euromédecine, Montpellier, France., Dubuc B; ALCEDIAG/Sys2Diag, CNRS UMR 9005, Parc Euromédecine, Montpellier, France., Vetter D; ALCEDIAG/Sys2Diag, CNRS UMR 9005, Parc Euromédecine, Montpellier, France., Dainat J; ALCEDIAG/Sys2Diag, CNRS UMR 9005, Parc Euromédecine, Montpellier, France., Lang JP; ALCEDIAG/Sys2Diag, CNRS UMR 9005, Parc Euromédecine, Montpellier, France; Les Toises. Center for psychiatry and psychotherapy, Lausanne, Switzerland., Gamma F; Les Toises. Center for psychiatry and psychotherapy, Lausanne, Switzerland., Weissmann D; ALCEDIAG/Sys2Diag, CNRS UMR 9005, Parc Euromédecine, Montpellier, France. Electronic address: dweissmann@alcediag-alcen.com.

Publikováno v: Journal of affective disorders [J Affect Disord] 2024 Jul 01; Vol. 356, pp. 385-393. Date of Electronic Publication: 2024 Apr 13.

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Euthymic and depressed bipolar patients are characterized by different RNA editing patterns in blood.

Autor: Hayashi MAF; Department of Pharmacology, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), Rua 3 de maio 100, Ed. INFAR, 3rd floor, SP CEP 04044-020, Brazil; National Institute for Translational Medicine (INCT-TM, CNPq/FAPESP/CAPES), Ribeirão Preto, Brazil. Electronic address: mhayashi@unifesp.br., Salvetat N; ALCEDIAG/Sys2Diag, CNRS UMR 9005, Parc Euromédecine, 1682 rue de la Valsière, Montpellier 34184, France., Cayzac C; ALCEDIAG/Sys2Diag, CNRS UMR 9005, Parc Euromédecine, 1682 rue de la Valsière, Montpellier 34184, France., Checa-Robles FJ; ALCEDIAG/Sys2Diag, CNRS UMR 9005, Parc Euromédecine, 1682 rue de la Valsière, Montpellier 34184, France., Dubuc B; ALCEDIAG/Sys2Diag, CNRS UMR 9005, Parc Euromédecine, 1682 rue de la Valsière, Montpellier 34184, France., Mereuze S; ALCEDIAG/Sys2Diag, CNRS UMR 9005, Parc Euromédecine, 1682 rue de la Valsière, Montpellier 34184, France., Nani JV; Department of Pharmacology, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), Rua 3 de maio 100, Ed. INFAR, 3rd floor, SP CEP 04044-020, Brazil; National Institute for Translational Medicine (INCT-TM, CNPq/FAPESP/CAPES), Ribeirão Preto, Brazil., Molina F; ALCEDIAG/Sys2Diag, CNRS UMR 9005, Parc Euromédecine, 1682 rue de la Valsière, Montpellier 34184, France., Brietzke E; Department of Psychiatry, Queen's University School of Medicine, Kingston, Canada., Weissmann D; ALCEDIAG/Sys2Diag, CNRS UMR 9005, Parc Euromédecine, 1682 rue de la Valsière, Montpellier 34184, France. Electronic address: dweissmann@alcediag-alcen.com.

Publikováno v: Psychiatry research [Psychiatry Res] 2023 Oct; Vol. 328, pp. 115422. Date of Electronic Publication: 2023 Aug 18.

Logical analysis of diffuse large B-cell lymphomas

Autor: Alexe, G., Alexe, S., Axelrod, D.E., Hammer, P.L. ^*, Weissmann, D.

Publikováno v: In Artificial Intelligence In Medicine 2005 34(3):235-267