Torsades de pointes

Autor: Weissenburger, J, Davy, J.-M

Publikováno v: In EMC-Cardiologie-Angeiologie 2004 1(2):123-139

σ2-Receptor Ligand-Mediated Inhibition of Inwardly Rectifying K+ Channels in the Heart

Autor: Isabelle Baró, Pascal Bousquet, Jean Daniel Ehrhardt, Borys Manoury, Diane Zimmermann, Laurent Monassier, Weissenburger J, Patrice Jaillon, Chloé Bellocq, Hugues Greney

Publikováno v: Journal of Pharmacology and Experimental Therapeutics
Journal of Pharmacology and Experimental Therapeutics, American Society for Pharmacology and Experimental Therapeutics, 2007, 322 (1), pp.341-350
Journal of Pharmacology and Experimental Therapeutics, 2007, 322 (1), pp.341-350

The sigma(2)-receptor agonist, ifenprodil, was suggested as an inhibitor of G protein-coupled inwardly rectifying potassium channels. Nevertheless, an analysis of the role of sigma(2) receptors in cardiac electrophysiology has never been done. This w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fb3eaee117c9ac77bf3181ad7d7bab5
https://doi.org/10.1124/jpet.107.122044

Effects of chronic treatment by amiodarone on transmural heterogeneity of canine ventricular repolarization in vivo: interactions with acute sotalol

Autor: Weissenburger J, J. Merot, Gérard Coutris, Flavien Charpentier, Jean-Marie Poirier

Publikováno v: Cardiovascular Research. 44:303-314

Objective: The present study was designed to examine the effects of chronic amiodarone on the different ventricular cell subtypes in situ and to evaluate its interactions with sotalol. Methods: Three groups of dogs were studied. Group I ( n =8) recei

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3858aae8170b1c1f28ea24913c65d35b
https://doi.org/10.1016/s0008-6363(99)00232-1

Plasma Itraconazole Concentrations in Patients With Neutropenia

Autor: Weissenburger J, Patrick Tilleul, Georges Cheymol, Francoise Isnard, Jean-Marie Poirier, Sebastien Hardy

Publikováno v: Therapeutic Drug Monitoring. 19:525-529

A group of 36 patients in the hematology department of Saint-Antoine Hospital, Paris, France, was on chemotherapy. The patients were also given antiacid drugs to prevent gastrointestinal toxicity and itraconazole as prophylaxis against aspergillosis.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::104c096de0533876ea96e47ec536b475
https://doi.org/10.1097/00007691-199710000-00007

Comparison of the Cardiac Electrophysiological Effects of Flecainide and Hydroquinidine in Anesthetized Dog

Autor: Harlé X, F. Chezalviel, Georges Cheymol, Weissenburger J, M. Biour, Jean-Marie Poirier, Jean-Marc Davy, O. Ertzbischoff

Publikováno v: Journal of Cardiovascular Pharmacology. 15:50-56

The concentration-dependent effects of flecainide and hydroquinidine were studied in closed-chest anesthetized dogs. The electrophysiological effects of three doses (i.v. infusions followed by an appropriate perfusion to plateau the plasma levels) of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2709f1655cb95b6c65005630e6939cae
https://doi.org/10.1097/00005344-199001000-00008