Effect of Hydrocortisone Therapy Initiated 7 to 14 Days After Birth on Mortality or Bronchopulmonary Dysplasia Among Very Preterm Infants Receiving Mechanical Ventilation

Autor: Onland, W., Cools, F., Kroon, A., Rademaker, K., Merkus, M.P., Dijk, P.H., Straaten, H.L. van, Pas, A.B.T., Mohns, T., Bruneel, E., Heijst, A.F. van, Kramer, B.W., Debeer, A., Zonnenberg, I., Marechal, Y., Blom, H., Plaskie, K., Offringa, M., Kaam, A.H. van, Nuytemans, D.H., Loo, M.V. de, Kemper, E.M., Vereeck, I., Heide-Jalving, M. van der, Kort, E. de, Cavartorta, E., Rassart, A., Eerdekens, A., Stuijvenberg, M., Matthijsse, R., Boode, W. de, Niemarkt, H., Hattum, I. van, Jebbink, L.G., Mulder-de Tollenaer, S.M., Tan, R., Theyskens, C., Weissenbruch, M. van, Dierckx, E., Rigo, V., Vrijlandt, E., Tweel, I. van der, Baal, C. van, Wildt, S. de, STOP-BPD Study Grp, Data Safety Monitoring Comm

Publikováno v: Journal of the American Medical Association, 321(4), 354-363
JAMA-Journal of the American Medical Association, 321(4), 354-363. American Medical Association
JAMA : the journal of the American Medical Association
Jama : Journal of the American Medical Association, 321, 354-363
Jama : Journal of the American Medical Association, 321, 4, pp. 354-363
Onland, W, Cools, F, Kroon, A, Rademaker, K, Merkus, M P, Dijk, P H, van Straaten, H L, te Pas, A B, Mohns, T, Bruneel, E, van Heijst, A F, Kramer, B W, Debeer, A, Zonnenberg, I, Marechal, Y, Blom, H, Plaskie, K, Offringa, M & van Kaam, A H 2019, ' Effect of Hydrocortisone Therapy Initiated 7 to 14 Days after Birth on Mortality or Bronchopulmonary Dysplasia among Very Preterm Infants Receiving Mechanical Ventilation: A Randomized Clinical Trial ', JAMA-Journal of the American Medical Association, vol. 321, no. 4, pp. 354-363 . https://doi.org/10.1001/jama.2018.21443
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 321(4), 354-363. AMER MEDICAL ASSOC
JAMA, 321(4), 354-363. American Medical Association

IMPORTANCE: Dexamethasone initiated after the first week of life reduces the rate of death or bronchopulmonary dysplasia (BPD) but may cause long-term adverse effects in very preterm infants. Hydrocortisone is increasingly used as an alternative, but

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8a7ccd7bb0b194a20f2a8a7a0fe345d
https://doi.org/10.1001/jama.2018.21443

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