Downregulation of MYCN through PI3K inhibition in mouse models of pediatric neural cancer

Autor: Gustafson, William, Cage, TA, Chanthery, Y, Chesler, L, Grimmer, M, Knight, Z, Shokat, K, Weiss, WA, Gustafson, WC

Publikováno v: Gustafson, William; Cage, TA; Chanthery, Y; Chesler, L; Grimmer, M; Knight, Z; et al.(2015). Downregulation of MYCN through PI3K inhibition in mouse models of pediatric neural cancer. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/1jb0r8xp

© 2015 Cage, Chanthery, Chesler, Grimmer, Knight, Shokat, Weiss and Gustafson.The MYCN proto-oncogene is associated with poor outcome across a broad range of pediatric tumors. While amplification of MYCN drives subsets of high-risk neuroblastoma and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::535297293a0bbd9eeaf91bfb4a69a4ac
http://www.escholarship.org/uc/item/1jb0r8xp

Cytogenetic prognostication within medulloblastoma subgroups

Autor: Shih, DJH, Northcott, PA, Remke, M, Korshunov, A, Ramaswamy, V, Kool, M, Luu, B, Yao, Y, Wang, X, Dubuc, AM, Garzia, L, Peacock, J, Mack, SC, Wu, X, Rolider, A, Morrissy, AS, Cavalli, FMG, Jones, DTW, Zitterbart, K, Faria, CC, Schüller, U, Kren, L, Kumabe, T, Tominaga, T, Ra, YS, Garami, M, Hauser, P, Chan, JA, Robinson, S, Bognár, L, Klekner, A, Saad, AG, Liau, LM, Albrecht, S, Fontebasso, A, Cinalli, G, De Antonellis, P, Zollo, M, Cooper, MK, Thompson, RC, Bailey, S, Lindsey, JC, Di Rocco, C, Massimi, L, Michiels, EMC, Scherer, SW, Phillips, JJ, Gupta, N, Fan, X, Muraszko, KM, Vibhakar, R, Eberhart, CG, Fouladi, M, Lach, B, Jung, S, Wechsler-Reya, RJ, Fèvre-Montange, M, Jouvet, A, Jabado, N, Pollack, IF, Weiss, WA, Lee, JY, Cho, BK, Kim, SK, Wang, KC, Leonard, JR, Rubin, JB, De Torres, C, Lavarino, C, Mora, J, Cho, YJ, Tabori, U, Olson, JM, Gajjar, A, Packer, RJ, Rutkowski, S, Pomeroy, SL, French, PJ, Kloosterhof, NK, Kros, JM, Van Meir, EG, Clifford, SC, Bourdeaut, F, Delattre, O, Doz, FF, Hawkins, CE, Malkin, D, Grajkowska, WA

Publikováno v: Shih, DJH; Northcott, PA; Remke, M; Korshunov, A; Ramaswamy, V; Kool, M; et al.(2014). Cytogenetic prognostication within medulloblastoma subgroups. Journal of Clinical Oncology, 32(9), 886-896. doi: 10.1200/JCO.2013.50.9539. UCLA: Retrieved from: http://www.escholarship.org/uc/item/52j0r1qj

Purpose: Medulloblastoma comprises four distinct molecular subgroups: WNT, SHH, Group 3, and Group 4. Current medulloblastoma protocols stratify patients based on clinical features: patient age, metastatic stage, extent of resection, and histologic v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::cfd12c97bf2de5fb87ef2e679987e309
http://www.escholarship.org/uc/item/52j0r1qj

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