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Akademický článek
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Autor:
Weiß Lily, Efferth Thomas
Publikováno v:
Experimental Hematology & Oncology, Vol 1, Iss 1, p 38 (2012)
Abstract Polo-like kinase 1 (Plk1) is an interesting molecule both as a biomarker and as a target for highly specific cancer therapy for several reasons. Firstly, it is over-expressed in many cancers and can serve as a biomarker to monitor treatment
Externí odkaz:
https://doaj.org/article/2a10cea40b8849fe8c5da7559ef764e1
Autor:
Mikhaylov V; The Simons Center for Systems Biology, Institute for Advanced Study, 1 Einstein Drive, Princeton, NJ 08540, USA. Electronic address: vmikhayl@ias.edu., Brambley CA; Department of Chemistry and Biochemistry and the Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA., Keller GLJ; Department of Chemistry and Biochemistry and the Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA., Arbuiso AG; Department of Chemistry and Biochemistry and the Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA., Weiss LI; Department of Chemistry and Biochemistry and the Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA., Baker BM; Department of Chemistry and Biochemistry and the Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA., Levine AJ; The Simons Center for Systems Biology, Institute for Advanced Study, 1 Einstein Drive, Princeton, NJ 08540, USA.
Publikováno v:
Structure (London, England : 1993) [Structure] 2024 Feb 01; Vol. 32 (2), pp. 228-241.e4. Date of Electronic Publication: 2023 Dec 18.
Autor:
Weiss A; From the Harvard Medical School, Boston MA (Weiss, Li, Desai, Tung, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, Chikarmane, Tayob, Fing, Tolaney, Winer, Mittendorf, Waks).; Breast Oncology Program, Dana-Farber Brigham Cancer Center, Boston MA (Weiss, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, DeMeo, Wrabel, Alberti, Chikarmane, King, Tolaney, Winer, Mittendorf, Waks).; Division of Breast Surgery, Department of Surgery (Weiss, Nakhlis, Dominici, King, Mittendorf)., Li T; From the Harvard Medical School, Boston MA (Weiss, Li, Desai, Tung, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, Chikarmane, Tayob, Fing, Tolaney, Winer, Mittendorf, Waks).; Department of Data Science (Li, Tayob)., Desai NV; From the Harvard Medical School, Boston MA (Weiss, Li, Desai, Tung, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, Chikarmane, Tayob, Fing, Tolaney, Winer, Mittendorf, Waks).; Division of Medical Oncology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston MA (Desai, Tung)., Tung NM; From the Harvard Medical School, Boston MA (Weiss, Li, Desai, Tung, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, Chikarmane, Tayob, Fing, Tolaney, Winer, Mittendorf, Waks).; Division of Medical Oncology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston MA (Desai, Tung)., Poorvu PD; From the Harvard Medical School, Boston MA (Weiss, Li, Desai, Tung, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, Chikarmane, Tayob, Fing, Tolaney, Winer, Mittendorf, Waks).; Breast Oncology Program, Dana-Farber Brigham Cancer Center, Boston MA (Weiss, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, DeMeo, Wrabel, Alberti, Chikarmane, King, Tolaney, Winer, Mittendorf, Waks).; Department of Medical Oncology (Poorvu, Partridge, Sinclair, Faggen, Constantine, Krop, Tolaney, Winer, Waks) Dana-Farber Cancer Institute, Boston MA., Partridge AH; From the Harvard Medical School, Boston MA (Weiss, Li, Desai, Tung, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, Chikarmane, Tayob, Fing, Tolaney, Winer, Mittendorf, Waks).; Breast Oncology Program, Dana-Farber Brigham Cancer Center, Boston MA (Weiss, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, DeMeo, Wrabel, Alberti, Chikarmane, King, Tolaney, Winer, Mittendorf, Waks).; Department of Medical Oncology (Poorvu, Partridge, Sinclair, Faggen, Constantine, Krop, Tolaney, Winer, Waks) Dana-Farber Cancer Institute, Boston MA., Nakhlis F; From the Harvard Medical School, Boston MA (Weiss, Li, Desai, Tung, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, Chikarmane, Tayob, Fing, Tolaney, Winer, Mittendorf, Waks).; Breast Oncology Program, Dana-Farber Brigham Cancer Center, Boston MA (Weiss, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, DeMeo, Wrabel, Alberti, Chikarmane, King, Tolaney, Winer, Mittendorf, Waks).; Division of Breast Surgery, Department of Surgery (Weiss, Nakhlis, Dominici, King, Mittendorf)., Dominici L; From the Harvard Medical School, Boston MA (Weiss, Li, Desai, Tung, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, Chikarmane, Tayob, Fing, Tolaney, Winer, Mittendorf, Waks).; Breast Oncology Program, Dana-Farber Brigham Cancer Center, Boston MA (Weiss, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, DeMeo, Wrabel, Alberti, Chikarmane, King, Tolaney, Winer, Mittendorf, Waks).; Division of Breast Surgery, Department of Surgery (Weiss, Nakhlis, Dominici, King, Mittendorf)., Sinclair N; From the Harvard Medical School, Boston MA (Weiss, Li, Desai, Tung, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, Chikarmane, Tayob, Fing, Tolaney, Winer, Mittendorf, Waks).; Breast Oncology Program, Dana-Farber Brigham Cancer Center, Boston MA (Weiss, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, DeMeo, Wrabel, Alberti, Chikarmane, King, Tolaney, Winer, Mittendorf, Waks).; Department of Medical Oncology (Poorvu, Partridge, Sinclair, Faggen, Constantine, Krop, Tolaney, Winer, Waks) Dana-Farber Cancer Institute, Boston MA., Spring LM; From the Harvard Medical School, Boston MA (Weiss, Li, Desai, Tung, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, Chikarmane, Tayob, Fing, Tolaney, Winer, Mittendorf, Waks).; Breast Oncology Program, Dana-Farber Brigham Cancer Center, Boston MA (Weiss, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, DeMeo, Wrabel, Alberti, Chikarmane, King, Tolaney, Winer, Mittendorf, Waks).; Division of Hematology-Oncology, Massachusetts General Hospital, Boston MA (Spring)., Faggen M; From the Harvard Medical School, Boston MA (Weiss, Li, Desai, Tung, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, Chikarmane, Tayob, Fing, Tolaney, Winer, Mittendorf, Waks).; Breast Oncology Program, Dana-Farber Brigham Cancer Center, Boston MA (Weiss, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, DeMeo, Wrabel, Alberti, Chikarmane, King, Tolaney, Winer, Mittendorf, Waks).; Department of Medical Oncology (Poorvu, Partridge, Sinclair, Faggen, Constantine, Krop, Tolaney, Winer, Waks) Dana-Farber Cancer Institute, Boston MA., Constantine M; From the Harvard Medical School, Boston MA (Weiss, Li, Desai, Tung, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, Chikarmane, Tayob, Fing, Tolaney, Winer, Mittendorf, Waks).; Breast Oncology Program, Dana-Farber Brigham Cancer Center, Boston MA (Weiss, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, DeMeo, Wrabel, Alberti, Chikarmane, King, Tolaney, Winer, Mittendorf, Waks).; Department of Medical Oncology (Poorvu, Partridge, Sinclair, Faggen, Constantine, Krop, Tolaney, Winer, Waks) Dana-Farber Cancer Institute, Boston MA., Krop IE; From the Harvard Medical School, Boston MA (Weiss, Li, Desai, Tung, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, Chikarmane, Tayob, Fing, Tolaney, Winer, Mittendorf, Waks).; Breast Oncology Program, Dana-Farber Brigham Cancer Center, Boston MA (Weiss, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, DeMeo, Wrabel, Alberti, Chikarmane, King, Tolaney, Winer, Mittendorf, Waks).; Department of Medical Oncology (Poorvu, Partridge, Sinclair, Faggen, Constantine, Krop, Tolaney, Winer, Waks) Dana-Farber Cancer Institute, Boston MA., DeMeo M; Breast Oncology Program, Dana-Farber Brigham Cancer Center, Boston MA (Weiss, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, DeMeo, Wrabel, Alberti, Chikarmane, King, Tolaney, Winer, Mittendorf, Waks)., Wrabel E; Breast Oncology Program, Dana-Farber Brigham Cancer Center, Boston MA (Weiss, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, DeMeo, Wrabel, Alberti, Chikarmane, King, Tolaney, Winer, Mittendorf, Waks)., Alberti J; Breast Oncology Program, Dana-Farber Brigham Cancer Center, Boston MA (Weiss, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, DeMeo, Wrabel, Alberti, Chikarmane, King, Tolaney, Winer, Mittendorf, Waks)., Chikarmane S; From the Harvard Medical School, Boston MA (Weiss, Li, Desai, Tung, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, Chikarmane, Tayob, Fing, Tolaney, Winer, Mittendorf, Waks).; Breast Oncology Program, Dana-Farber Brigham Cancer Center, Boston MA (Weiss, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, DeMeo, Wrabel, Alberti, Chikarmane, King, Tolaney, Winer, Mittendorf, Waks).; Department of Radiology (Chikarmane), Brigham and Women's Hospital, Boston MA., Tayob N; From the Harvard Medical School, Boston MA (Weiss, Li, Desai, Tung, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, Chikarmane, Tayob, Fing, Tolaney, Winer, Mittendorf, Waks).; Department of Data Science (Li, Tayob)., King TA; Breast Oncology Program, Dana-Farber Brigham Cancer Center, Boston MA (Weiss, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, DeMeo, Wrabel, Alberti, Chikarmane, King, Tolaney, Winer, Mittendorf, Waks).; Division of Breast Surgery, Department of Surgery (Weiss, Nakhlis, Dominici, King, Mittendorf)., Tolaney SM; From the Harvard Medical School, Boston MA (Weiss, Li, Desai, Tung, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, Chikarmane, Tayob, Fing, Tolaney, Winer, Mittendorf, Waks).; Breast Oncology Program, Dana-Farber Brigham Cancer Center, Boston MA (Weiss, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, DeMeo, Wrabel, Alberti, Chikarmane, King, Tolaney, Winer, Mittendorf, Waks).; Department of Medical Oncology (Poorvu, Partridge, Sinclair, Faggen, Constantine, Krop, Tolaney, Winer, Waks) Dana-Farber Cancer Institute, Boston MA., Winer EP; From the Harvard Medical School, Boston MA (Weiss, Li, Desai, Tung, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, Chikarmane, Tayob, Fing, Tolaney, Winer, Mittendorf, Waks).; Breast Oncology Program, Dana-Farber Brigham Cancer Center, Boston MA (Weiss, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, DeMeo, Wrabel, Alberti, Chikarmane, King, Tolaney, Winer, Mittendorf, Waks).; Department of Medical Oncology (Poorvu, Partridge, Sinclair, Faggen, Constantine, Krop, Tolaney, Winer, Waks) Dana-Farber Cancer Institute, Boston MA., Mittendorf EA; From the Harvard Medical School, Boston MA (Weiss, Li, Desai, Tung, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, Chikarmane, Tayob, Fing, Tolaney, Winer, Mittendorf, Waks).; Breast Oncology Program, Dana-Farber Brigham Cancer Center, Boston MA (Weiss, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, DeMeo, Wrabel, Alberti, Chikarmane, King, Tolaney, Winer, Mittendorf, Waks).; Division of Breast Surgery, Department of Surgery (Weiss, Nakhlis, Dominici, King, Mittendorf)., Waks AG; From the Harvard Medical School, Boston MA (Weiss, Li, Desai, Tung, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, Chikarmane, Tayob, Fing, Tolaney, Winer, Mittendorf, Waks).; Breast Oncology Program, Dana-Farber Brigham Cancer Center, Boston MA (Weiss, Poorvu, Partridge, Nakhlis, Dominici, Sinclair, Spring, Faggen, Constantine, Krop, DeMeo, Wrabel, Alberti, Chikarmane, King, Tolaney, Winer, Mittendorf, Waks).; Department of Medical Oncology (Poorvu, Partridge, Sinclair, Faggen, Constantine, Krop, Tolaney, Winer, Waks) Dana-Farber Cancer Institute, Boston MA.
Publikováno v:
Journal of the American College of Surgeons [J Am Coll Surg] 2023 Aug 01; Vol. 237 (2), pp. 247-256. Date of Electronic Publication: 2023 May 17.
Autor:
Singh NK; Department of Chemistry & Biochemistry and the Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA., Alonso JA; Department of Chemistry & Biochemistry and the Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN, USA.; AbbVie, Inc. 1N Waukegan Rd, North Chicago, IL, USA., Devlin JR; Department of Chemistry & Biochemistry and the Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN, USA.; Nature Technology Corporation, 4701 Innovation Drive 103, Lincoln, NE, USA., Keller GLJ; Department of Chemistry & Biochemistry and the Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN, USA.; Amgen Inc., One Amgen Center Drive, Thousand Oaks, CA, USA., Gray GI; Department of Chemistry & Biochemistry and the Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN, USA., Chiranjivi AK; Department of Chemistry & Biochemistry and the Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN, USA., Foote SG; Department of Chemistry & Biochemistry and the Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN, USA., Landau LM; Department of Chemistry & Biochemistry and the Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN, USA.; Harvard Medical School, Division of Gastroenterology, Boston Children's Hospital, Boston, MA, USA., Arbuiso AG; Department of Chemistry & Biochemistry and the Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN, USA., Weiss LI; Department of Chemistry & Biochemistry and the Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN, USA., Rosenberg AM; Department of Chemistry & Biochemistry and the Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN, USA., Hellman LM; Department of Chemistry & Biochemistry and the Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN, USA.; Department of Physical and Life Sciences, Nevada State College, Henderson, NV, USA., Nishimura MI; Department of Surgery, Cardinal Bernardin Cancer Center, Loyola University Chicago, Maywood, IL, USA., Baker BM; Department of Chemistry & Biochemistry and the Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN, USA. brian-baker@nd.edu.
Publikováno v:
Nature communications [Nat Commun] 2022 Nov 23; Vol. 13 (1), pp. 7189. Date of Electronic Publication: 2022 Nov 23.
Autor:
Keller GLJ; Department of Chemistry & Biochemistry and the Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN, United States., Weiss LI; Department of Chemistry & Biochemistry and the Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN, United States., Baker BM; Department of Chemistry & Biochemistry and the Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN, United States.
Publikováno v:
Frontiers in immunology [Front Immunol] 2022 Apr 25; Vol. 13, pp. 887759. Date of Electronic Publication: 2022 Apr 25 (Print Publication: 2022).