The Tumor Suppressor MIG6 Controls Mitotic Progression and the G2/M DNA Damage Checkpoint by Stabilizing the WEE1 Kinase

Autor: Sasaki, Mari, Terabayashi, Takeshi, Weiss, Stefanie M., Ferby, Ingvar

MIG6 is an important tumor suppressor that binds to and negatively regulates epidermal growth factor receptor (EGFR). Here, we report an EGFR-independent function for MIG6 as an integral component of the cell cycle machinery. We found that depletion

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http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-357232

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IRSp53 Links the Enterohemorrhagic E. coli Effectors Tir and EspFU for Actin Pedestal Formation.

Autor: Weiss, Stefanie M., Ladwein, Markus, Schmidt, Dorothea, Ehinger, Julia, Lommel, Silvia, Städing, Kai, Beutling, Ulrike, Disanza, Andrea, Frank, Ronald, Jänsch, Lothar, Scita, Giorgio, Gunzer, Florian, Rottner, Klemens, Stradal, Theresia E.B.

Publikováno v: Cell Host & Microbe; Mar2009, Vol. 5 Issue 3, p244-258, 15p

The Tumor Suppressor MIG6 Controls Mitotic Progression and the G2/M DNA Damage Checkpoint by Stabilizing the WEE1 Kinase.

Autor: Sasaki M; Department of Medical Biochemistry and Microbiology, Science for Life Laboratory, Uppsala University, Box 582, 751 23 Uppsala, Sweden., Terabayashi T; Department of Medical Biochemistry and Microbiology, Science for Life Laboratory, Uppsala University, Box 582, 751 23 Uppsala, Sweden., Weiss SM; Department of Medical Biochemistry and Microbiology, Science for Life Laboratory, Uppsala University, Box 582, 751 23 Uppsala, Sweden., Ferby I; Department of Medical Biochemistry and Microbiology, Science for Life Laboratory, Uppsala University, Box 582, 751 23 Uppsala, Sweden. Electronic address: ingvar.ferby@imbim.uu.se.

Publikováno v: Cell reports [Cell Rep] 2018 Jul 31; Vol. 24 (5), pp. 1278-1289.