Association of maternal fish consumption and ω-3 supplement use during pregnancy with child autism-related outcomes: results from a cohort consortium analysis

Autor: Smith, PB, Newby, KL, Jacobson, LP, Catellier, DJ, Gershon, R, Cella, D, Alshawabkeh, AN, Cordero, J, Meeker, J, Aschner, J, Teitelbaum, SL, Stroustrup, A, Mansbach, JM, Spergel, JM, Samuels-Kalow, ME, Stevenson, MD, Bauer, CS, Koinis Mitchell, D, Deoni, S, D’Sa, V, Duarte, CS, Monk, C, Posner, J, Canino, G, Seroogy, C, Bendixsen, C, Hertz-Picciotto, I, Keenan, K, Karr, C, Tylavsky, F, Mason, A, Zhao, Q, Sathyanarayana, S, LeWinn, KZ, Lester, B, Carter, B, Pastyrnak, S, Neal, C, Smith, L, Helderman, J, Weiss, ST, Litonjua, A, O’Connor, G, Zeiger, R, Bacharier, L, Volk, H, Ozonoff, S, Schmidt, R, Simhan, H, Kerver, JM, Barone, C, Fussman, C, Paneth, N, Elliott, M, Ruden, D, Porucznik, C, Giardino, A, Innocenti, M, Silver, R, Conradt, E, Bosquet-Enlow, M, Huddleston, K, Nguyen, R, Trasande, L, Swan, S, Lyall, Kristen, Westlake, Matt, Musci, Rashelle J, Gachigi, Kennedy, Barrett, Emily S, Bastain, Theresa M, Bush, Nicole R, Buss, Claudia, Camargo, Carlos A, Jr., Croen, Lisa A, Dabelea, Dana, Dunlop, Anne L, Elliott, Amy J, Ferrara, Assiamira, Ghassabian, Akhgar, Gern, James E, Hare, Marion E, Hertz-Picciotto, Irva, Hipwell, Alison E, Hockett, Christine W, Karagas, Margaret R, Lugo-Candelas, Claudia, O’Connor, Thomas G, Schmidt, Rebecca J, Stanford, Joseph B, Straughen, Jennifer K, Shuster, Coral L, Wright, Robert O, Wright, Rosalind J, Zhao, Qi, Oken, Emily

Publikováno v: In The American Journal of Clinical Nutrition September 2024 120(3):583-592

Circulating microRNAs associated with bronchodilator response in childhood asthma.

Autor: Sharma R; Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. rersh@channing.harvard.edu., Tiwari A; Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA., Kho AT; Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Computational Health Informatics Program, Boston Children's Hospital, Boston, MA, USA., Wang AL; Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Srivastava U; Division of Pediatric Respiratory Medicine, University of California San Diego and Rady Children's Hospital, San Diego, CA, USA.; Department of MEDCSC Neurodevelopment (Child Study Center), Yale University School of Medicine, New Haven, CT, USA., Piparia S; Division of Pediatric Respiratory Medicine, University of California San Diego and Rady Children's Hospital, San Diego, CA, USA., Desai B; Division of Pediatric Respiratory Medicine, University of California San Diego and Rady Children's Hospital, San Diego, CA, USA., Wong R; Division of Pediatric Respiratory Medicine, University of California San Diego and Rady Children's Hospital, San Diego, CA, USA., Celedón JC; Division of Pediatric Pulmonary Medicine, University of Pittsburgh, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, USA., Peters SP; Department of Medicine, Wake Forest University, Winston-Salem, NC, USA., Smith LJ; Department of Medicine, Northwestern University, Chicago, IL, USA., Irvin CG; Pulmonary and Critical Care Medicine, Larner College of Medicine, University of Vermont, Burlington, VT, USA., Castro M; University of Kansas School of Medicine, Kansas City, KS, USA., Weiss ST; Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Tantisira KG; Division of Pediatric Respiratory Medicine, University of California San Diego and Rady Children's Hospital, San Diego, CA, USA., McGeachie MJ; Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

Publikováno v: BMC pulmonary medicine [BMC Pulm Med] 2024 Nov 04; Vol. 24 (1), pp. 553. Date of Electronic Publication: 2024 Nov 04.

Genetics of Latin American Diversity Project: Insights into population genetics and association studies in admixed groups in the Americas.

Autor: Borda V; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201, USA; University of Maryland Institute for Health Computing, University of Maryland School of Medicine, North Bethesda, MD 20852, USA. Electronic address: vicbp1@gmail.com., Loesch DP; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Guo B; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Laboulaye R; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Veliz-Otani D; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201, USA., French JN; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Leal TP; Lerner Research Institute, Genomic Medicine, Cleveland Clinic, Cleveland, OH, USA., Gogarten SM; Department of Biostatistics, University of Washington, Seattle, WA, USA., Ikpe S; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Gouveia MH; Center for Research on Genomics and Global Health, National Human Genome Research Institute, NIH, Bethesda, MD 20892, USA., Mendes M; Department of Genetics, Ecology, and Evolution, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil., Abecasis GR; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Alvim I; Department of Genetics, Ecology, and Evolution, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil., Arboleda-Bustos CE; Neuroscience and Cell Death Research Groups, Medical School and Genetic Institute, Universidad Nacional de Colombia, Bogota, Colombia., Arboleda G; Neuroscience and Cell Death Research Groups, Medical School and Genetic Institute, Universidad Nacional de Colombia, Bogota, Colombia., Arboleda H; Neuroscience and Cell Death Research Groups, Medical School and Genetic Institute, Universidad Nacional de Colombia, Bogota, Colombia., Barreto ML; Instituto de Saúde Coletiva, Universidade Federal da Bahia, Salvador, BA 40110-040, Brazil., Barwick L; LTRC Data Coordinating Center, The Emmes Company, Rockville, MD, USA., Bezzera MA; Department of Genetics, Federal University of Pernambuco, Av. Prof. Moraes Rego, 1235, Recife, PE 50670-901, Brazil., Blangero J; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA., Borges V; Movement Disorders Unit, Department of Neurology and Neurosurgery, Universidade Federal de São Paulo, São Paulo, Brazil., Caceres O; Instituto Nacional de Salud, Lima, Peru; Facultad de Ciencias de la Salud, Universidad Científica del Sur, Lima, Peru., Cai J; Department of Biostatistics, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Chana-Cuevas P; CETRAM, Facultad de Ciencias Médicas, Universidad de Santiago de Chile, Santiago, Chile., Chen Z; Keck School of Medicine, University of Southern California, Los Angeles, Los Angeles, CA, USA., Custer B; Vitalant Research Institute, San Francisco, CA, USA., Dean M; Laboratory of Genomic Diversity, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, MD, USA., Dinardo C; Instituto de Medicina Tropical, University of São Paulo, São Paulo, Brazil., Domingos I; Department of Genetics, Federal University of Pernambuco, Av. Prof. Moraes Rego, 1235, Recife, PE 50670-901, Brazil., Duggirala R; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA., Dieguez E; Neurology Institute, Universidad de la República, Montevideo, Uruguay., Fernandez W; Neuroscience and Cell Death Research Groups, Medical School and Genetic Institute, Universidad Nacional de Colombia, Bogota, Colombia., Ferraz HB; Movement Disorders Unit, Department of Neurology and Neurosurgery, Universidade Federal de São Paulo, São Paulo, Brazil., Gilliland F; Keck School of Medicine, University of Southern California, Los Angeles, Los Angeles, CA, USA., Guio H; Instituto Nacional de Salud, Lima, Peru; INBIOMEDIC Research Center, Lima, Peru; Universidad de Huánuco, Huánuco, Peru., Horta B; Faculdade de Medicina, Departamento de Medicina Social, Universidade Federal de Pelotas, Pelotas, RS, Brazil., Curran JE; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA., Johnsen JM; Bloodworks Northwest Research Institute, Seattle, WA, USA., Kaplan RC; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA., Kelly S; Vitalant Research Institute, San Francisco, CA, USA; UCSF Benioff Children's Hospital, University of California, San Francisco, Oakland, CA, USA., Kenny EE; Icahn School of Medicine at Mount Sinai, New York, NY, USA., Konkle BA; Department of Medicine, University of Washington, Seattle, WA, USA., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA., Lescano A; Neurology Institute, Universidad de la República, Montevideo, Uruguay., Lima-Costa MF; Instituto de Pesquisas René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, MG, Brazil., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Manichaikul A; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA., Meyers DA; Division of Genetics, Genomics, and Precision Medicine, University of Arizona, Tucson, AZ, USA., Naslavsky MS; Human Genome and Stem Cell Research Center, University of São Paulo, São Paulo, SP, Brazil., Nickerson DA; Department of Genome Sciences, University of Washington, Seattle, WA, USA., North KE; Department of Epidemiology, Gillings School of Global Public Health, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Padilla C; Instituto Nacional de Salud, Lima, Peru., Preuss M; Icahn School of Medicine at Mount Sinai, New York, NY, USA., Raggio V; Genetics Department, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay., Reiner AP; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA; Department of Epidemiology, University of Washington, Seattle, WA, USA., Rich SS; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA., Rieder CR; Departamento de Neurologia, Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil., Rienstra M; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Rotter JI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA USA., Rundek T; Department of Neurology, Miller School of Medicine, and The Evelyn F. McKnight Brain Institute, University of Miami, Miami, FL, USA., Sacco RL; Department of Neurology, Miller School of Medicine, and The Evelyn F. McKnight Brain Institute, University of Miami, Miami, FL, USA., Sanchez C; Instituto Nacional de Salud, Lima, Peru., Sankaran VG; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Santos-Lobato BL; Instituto de Ciências da Saúde, Universidade Federal do Pará, Belém, Brazil., Schumacher-Schuh AF; Departamento de Farmacologia, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil; Serviço de Neurologia, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil., Scliar MO; Human Genome and Stem Cell Research Center, University of São Paulo, São Paulo, SP, Brazil., Silverman EK; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Sofer T; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Harvard Medical School, Boston, MA USA., Lasky-Su J; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Tumas V; Ribeirão Preto Medical School, Universidade de São Paulo, Ribeirão Preto, Brazil., Weiss ST; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Mata IF; University of Maryland Institute for Health Computing, University of Maryland School of Medicine, North Bethesda, MD 20852, USA., Hernandez RD; Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, USA; Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA; Quantitative Biosciences Institute, University of California, San Francisco, San Francisco, CA, USA; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA 94143, USA., Tarazona-Santos E; Department of Genetics, Ecology, and Evolution, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil; Facultad de Salud Pública y Administración. Universidad Peruana Cayetano Heredia, Lima, Peru., O'Connor TD; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201, USA; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA; Program in Health Equity and Population Health, University of Maryland School of Medicine, Baltimore, MD 21201, USA; Program in Personalized Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA. Electronic address: timothydoconnor@gmail.com.

Publikováno v: Cell genomics [Cell Genom] 2024 Oct 29, pp. 100692. Date of Electronic Publication: 2024 Oct 29.

Vitamin D beyond the blood: Tissue distribution of vitamin D metabolites after supplementation.

Autor: Shadid ILC; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Clinical Pharmacy & Toxicology, Leiden University Medical Center, Leiden, the Netherlands., Guchelaar HJ; Department of Clinical Pharmacy & Toxicology, Leiden University Medical Center, Leiden, the Netherlands., Weiss ST; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Mirzakhani H; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address: hoomi@post.harvard.edu.

Publikováno v: Life sciences [Life Sci] 2024 Oct 15; Vol. 355, pp. 122942. Date of Electronic Publication: 2024 Aug 10.

Whole-genome sequencing in 333,100 individuals reveals rare non-coding single variant and aggregate associations with height.

Autor: Hawkes G; Clinical and Biomedical Sciences, University of Exeter, Exeter, UK. g.hawkes2@exeter.ac.uk., Beaumont RN; Clinical and Biomedical Sciences, University of Exeter, Exeter, UK., Li Z; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Mandla R; Department of Medicine, Harvard Medical School, Broad Institute, Boston, Massachusetts, USA., Li X; Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Albert CM; Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Arnett DK; Provost Office, University of South Carolina, Columbia, SC, USA., Ashley-Koch AE; Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA., Ashrani AA; Division of Hematology, Department of Medicine, Mayo Clinic Rochester, Rochester, MN, USA., Barnes KC; Department of Medicine, School of Medicine, University of Colorado, Aurora, CO, USA., Boerwinkle E; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Brody JA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Carson AP; Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA., Chami N; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Chen YI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Chung MK; Department of Cardiovascular Medicine, Heart, Vascular & Thoracic Institute, Cleveland, OH, USA., Curran JE; Department of Human Genetics and South Texas Diabetes and Obesity Institute, School of Medicine, The University of Texas Rio Grande Valley, Brownsville, TX, USA., Darbar D; Division of Cardiology, Department of Medicine, University of Illinois Chicago, Chicago, IL, USA., Ellinor PT; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA., Fornage M; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Gordeuk VR; Department of Medicine, School of Medicine, University of Illinois at Chicago, Chicago, IL, USA., Guo X; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., He J; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA., Hwu CM; Section of Endocrinology and Metabolism, Department of Medicine, Taipei Veterans General Hospital, Taipei City, Taiwan., Kalyani RR; GeneSTAR Research Program, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Kaplan R; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA., Kardia SLR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Lubitz SA; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA., Minster RL; Department of Human Genetics, University of Pittsburgh, Pittsburgh, PA, USA., Naseri T; Naseri & Associates Public Health Consultancy Firm and Family Health Clinic, Apia, Samoa.; International Health Institute, Brown University, Providence, Rhode Island, US., Viali S; Oceania University of Medicine, Apia, Samoa.; School of Medicine, National University of Samoa, Apia, Samoa.; Dept of Chronic Disease Epidemiology, Yale University, New Haven, Connecticut, US., Mitchell BD; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Murabito JM; Boston University's and National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA, USA., Palmer ND; Department of Biochemistry, Wake Forest University School of Medicine, Winston-, Salem, NC, USA., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Departments of Medicine, Epidemiology, and Health Systems and Population Health, University of Washington, Seattle, WA, USA., Redline S; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA., Shoemaker MB; Department of Medicine, Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Silverman EK; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Telen MJ; Department of Medicine, Duke University School of Medicine, Durham, NC, USA., Weiss ST; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Yanek LR; GeneSTAR Research Program, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Zhou H; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Liu CT; Department of Biostatistics, School of Public Health, Boston University, Boston, MA, USA., North KE; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Justice AE; Population Health Sciences, Geisinger, Danville, PA, USA., Locke JM; Clinical and Biomedical Sciences, University of Exeter, Exeter, UK., Owens N; Clinical and Biomedical Sciences, University of Exeter, Exeter, UK., Murray A; Clinical and Biomedical Sciences, University of Exeter, Exeter, UK., Patel K; Clinical and Biomedical Sciences, University of Exeter, Exeter, UK., Frayling TM; Clinical and Biomedical Sciences, University of Exeter, Exeter, UK., Wright CF; Clinical and Biomedical Sciences, University of Exeter, Exeter, UK., Wood AR; Clinical and Biomedical Sciences, University of Exeter, Exeter, UK., Lin X; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Department of Statistics, Harvard University, Cambridge, MA, USA., Manning A; Department of Medicine, Harvard Medical School, Broad Institute, Boston, Massachusetts, USA., Weedon MN; Clinical and Biomedical Sciences, University of Exeter, Exeter, UK. m.n.weedon@exeter.ac.uk.

Publikováno v: Nature communications [Nat Commun] 2024 Oct 03; Vol. 15 (1), pp. 8549. Date of Electronic Publication: 2024 Oct 03.