Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Mouse screen reveals multiple new genes underlying mouse and human hearing loss

Autor: Ingham, Neil J, Pearson, Selina A, Vancollie, Valerie E, Rook, Victoria, Lewis, Morag A, Chen, Jing, Buniello, Annalisa, Martelletti, Elisa, Preite, Lorenzo, Lam, Chi Chung, Weiss, Felix D, Powis, Zӧe, Suwannarat, Pim, Lelliott, Christopher J, Dawson, Sally J, White, Jacqueline K, Steel, Karen P

Publikováno v: PLoS Biology, Vol 17, Iss 4, p e3000194 (2019)

Adult-onset hearing loss is very common, but we know little about the underlying molecular pathogenesis impeding the development of therapies. We took a genetic approach to identify new molecules involved in hearing loss by screening a large cohort o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8e238e55d70e29ccae1179d3bb0a185
https://doaj.org/article/d4fe6f45bed545a7b63c0342d4aa004a

Abstracts of papers presented at the 29^th Genetic Society's Mammalian Genetics and Development Workshop held at the UCL Great Ormond Street Institute of Child Health, University College London on Thursday 29^th November 2018.

Autor: Greene, Nicholas D. E., Copp, Andrew J., Andoniadou, Cynthia L., Cannavo, Claudia, Cleverley, K., Tosh, J. L., Noy, S., Lana-Elola, E., Tybulewicz, V., Fisher, E. M. C., Wiseman, F. K., Calderon, Lesly, Weiss, Felix D, Carroll, Thomas, Irvine, Elaine E., Dharmalingam, Gopuraja, Tossell, Kyoko, De Paola, Vincenzo, Whilding, Chad, Ungless, Mark A.

Publikováno v: Genetics Research; Jan2019, Vol. 101, pN.PAG-N.PAG, 5p

Neuronal genes deregulated in Cornelia de Lange Syndrome respond to removal and re-expression of cohesin.

Autor: Weiss FD; Lymphocyte Development Group, Epigenetics Section, MRC London Institute of Medical Sciences, Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK.; Institute of Innate Immunity, University of Bonn, Bonn, Germany., Calderon L; Lymphocyte Development Group, Epigenetics Section, MRC London Institute of Medical Sciences, Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK.; Research Institute of Molecular Pathology, Vienna, Austria., Wang YF; MRC London Institute of Medical Sciences, Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK., Georgieva R; Lymphocyte Development Group, Epigenetics Section, MRC London Institute of Medical Sciences, Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK.; Computational Regulatory Genomics Group, Epigenetics Section, MRC London Institute of Medical Sciences, Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK., Guo Y; Lymphocyte Development Group, Epigenetics Section, MRC London Institute of Medical Sciences, Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK.; School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China., Cvetesic N; Computational Regulatory Genomics Group, Epigenetics Section, MRC London Institute of Medical Sciences, Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK., Kaur M; Division of Human Genetics, The Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA., Dharmalingam G; MRC London Institute of Medical Sciences, Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK., Krantz ID; Division of Human Genetics, The Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.; The Perelman School of Medicine at The University of Pennsylvania, Philadelphia, PA, USA.; Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA, USA., Lenhard B; Computational Regulatory Genomics Group, Epigenetics Section, MRC London Institute of Medical Sciences, Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK.; Sars International Centre for Marine Molecular Biology, University of Bergen, Bergen, Norway., Fisher AG; Lymphocyte Development Group, Epigenetics Section, MRC London Institute of Medical Sciences, Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK., Merkenschlager M; Lymphocyte Development Group, Epigenetics Section, MRC London Institute of Medical Sciences, Institute of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK. matthias.merkenschlager@lms.mrc.ac.uk.

Publikováno v: Nature communications [Nat Commun] 2021 May 18; Vol. 12 (1), pp. 2919. Date of Electronic Publication: 2021 May 18.