Loss of mucosal tolerance to glycoprotein 2 isoform 1 is a potential novel diagnostic biomarker for cholangiocarcinoma.

Autor: Xia CS; Department of Clinical Laboratory, Peking University People's Hospital, Beijing, China., Krawczyk M; Department of Medicine II, Saarland University Medical Center, Saarland University, Homburg, Germany; Laboratory of Metabolic Liver Diseases, Department of General, Transplant and Liver Surgery, Centre for Preclinical Research, Medical University of Warsaw, Warsaw, Poland., Di C; Department of Clinical Laboratory, Peking University People's Hospital, Beijing, China., Krupa Ł; Department of Gastroenterology and Hepatology with Internal Disease Unit, Teaching Hospital No 1 in Rzeszów, Medical Department, University of Rzeszów, Poland., Kruk B; Laboratory of Metabolic Liver Diseases, Department of General, Transplant and Liver Surgery, Centre for Preclinical Research, Medical University of Warsaw, Warsaw, Poland., Krawczyk P; Department of General, Transplant and Liver Surgery, Medical University of Warsaw, Poland., Milkiewicz P; Liver and Internal Medicine Unit, Department of General, Transplant and Liver Surgery, Medical University of Warsaw, 02-091 Warsaw, Poland; Translational Medicine Group, Pomeranian Medical University, Szczecin, Poland., Bao H; Department of Clinical Laboratory, Peking University People's Hospital, Beijing, China., He X; Department of Clinical Laboratory, Peking University People's Hospital, Beijing, China., Liu D; Department of Clinical Laboratory, Peking University People's Hospital, Beijing, China., Fan C; Department of Clinical Laboratory, Peking University People's Hospital, Beijing, China., Nasser A; Medipan GmbH, R/D Department, Dahlewitz, Germany., Lopens S; Medipan GmbH, R/D Department, Dahlewitz, Germany; Institute of Biotechnology, Faculty Environment and Natural Sciences, Brandenburg University of Technology Cottbus-Senftenberg, Senftenberg, Germany., Weiss FU; Department of Medicine A, University Medicine Greifswald, Greifswald, Germany., Frost F; Department of Medicine A, University Medicine Greifswald, Greifswald, Germany., Schierack P; Institute of Biotechnology, Faculty Environment and Natural Sciences, Brandenburg University of Technology Cottbus-Senftenberg, Senftenberg, Germany; Faculty of Health Sciences Brandenburg, Brandenburg University of Technology Cottbus-Senftenberg, Senftenberg, Germany., Roggenbuck D; Medipan GmbH, R/D Department, Dahlewitz, Germany; Institute of Biotechnology, Faculty Environment and Natural Sciences, Brandenburg University of Technology Cottbus-Senftenberg, Senftenberg, Germany; Faculty of Health Sciences Brandenburg, Brandenburg University of Technology Cottbus-Senftenberg, Senftenberg, Germany., Liu Y; National Center for Clinical Laboratories, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing Hospital/National Center of Gerontology, Beijing 100730, PR China. Electronic address: yudongliu1983@126.com.

Publikováno v: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver [Dig Liver Dis] 2025 Jan; Vol. 57 (1), pp. 14-22. Date of Electronic Publication: 2024 Jun 08.

Fecal glycoprotein 2 is a marker of gut microbiota dysbiosis and systemic inflammation.

Autor: Frost F; Department of Medicine A, University Medicine Greifswald, Ferdinand-Sauerbruch- Straße, 17475, Greifswald, Germany., Weiss S; Department of Medicine A, University Medicine Greifswald, Ferdinand-Sauerbruch- Straße, 17475, Greifswald, Germany.; Department of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Hertel J; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany., Rühlemann M; Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany., Bang C; Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany., Franke A; Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany., Nauck M; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany., Dörr M; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany., Völzke H; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany., Roggenbuck D; Institute of Biotechnology, Faculty Environment and Natural Sciences, Brandenburg University of Technology Cottbus-Senftenberg, Senftenberg, Germany.; Faculty of Health Sciences Brandenburg, Brandenburg University of Technology Cottbus-Senftenberg, Senftenberg, Germany., Schierack P; Institute of Biotechnology, Faculty Environment and Natural Sciences, Brandenburg University of Technology Cottbus-Senftenberg, Senftenberg, Germany.; Faculty of Health Sciences Brandenburg, Brandenburg University of Technology Cottbus-Senftenberg, Senftenberg, Germany., Völker U; Department of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Homuth G; Department of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Aghdassi AA; Department of Medicine A, University Medicine Greifswald, Ferdinand-Sauerbruch- Straße, 17475, Greifswald, Germany., Sendler M; Department of Medicine A, University Medicine Greifswald, Ferdinand-Sauerbruch- Straße, 17475, Greifswald, Germany., Lerch MM; Department of Medicine A, University Medicine Greifswald, Ferdinand-Sauerbruch- Straße, 17475, Greifswald, Germany., Weiss FU; Department of Medicine A, University Medicine Greifswald, Ferdinand-Sauerbruch- Straße, 17475, Greifswald, Germany. ulrich.weiss@med.uni-greifswald.de.

Publikováno v: Gut pathogens [Gut Pathog] 2024 Oct 19; Vol. 16 (1), pp. 60. Date of Electronic Publication: 2024 Oct 19.

Initiation of acute pancreatitis in mice is independent of fusion between lysosomes and zymogen granules.

Autor: Zierke L; Department of Medicine A, University Medicine Greifswald, Ferdinand-Sauerbruch Str, 17475, Greifswald, Germany., John D; Department of Medicine A, University Medicine Greifswald, Ferdinand-Sauerbruch Str, 17475, Greifswald, Germany., Gischke M; Department of Medicine A, University Medicine Greifswald, Ferdinand-Sauerbruch Str, 17475, Greifswald, Germany., Tran QT; Department of Medicine A, University Medicine Greifswald, Ferdinand-Sauerbruch Str, 17475, Greifswald, Germany.; Department of Internal Medicine, Hue University, Hue, Vietnam., Sendler M; Department of Medicine A, University Medicine Greifswald, Ferdinand-Sauerbruch Str, 17475, Greifswald, Germany., Weiss FU; Department of Medicine A, University Medicine Greifswald, Ferdinand-Sauerbruch Str, 17475, Greifswald, Germany., Bornscheuer UT; Institute of Biochemistry, Department of Biotechnology & Enzyme Catalysis, University of Greifswald, Greifswald, Germany., Ritter C; Department of Pharmacy, University of Greifswald, Greifswald, Germany., Lerch MM; Ludwig-Maximilians University Munich, Munich, Germany., Aghdassi AA; Department of Medicine A, University Medicine Greifswald, Ferdinand-Sauerbruch Str, 17475, Greifswald, Germany. ali.aghdassi@med.uni-greifswald.de.

Publikováno v: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2024 May 06; Vol. 81 (1), pp. 207. Date of Electronic Publication: 2024 May 06.

Immune response mechanisms in acute and chronic pancreatitis: strategies for therapeutic intervention.

Autor: Glaubitz J; Department of Medicine A, University Medicine, University of Greifswald, Greifswald, Germany., Asgarbeik S; Department of Medicine A, University Medicine, University of Greifswald, Greifswald, Germany., Lange R; Department of Medicine A, University Medicine, University of Greifswald, Greifswald, Germany., Mazloum H; Department of Medicine A, University Medicine, University of Greifswald, Greifswald, Germany., Elsheikh H; Department of Medicine A, University Medicine, University of Greifswald, Greifswald, Germany., Weiss FU; Department of Medicine A, University Medicine, University of Greifswald, Greifswald, Germany., Sendler M; Department of Medicine A, University Medicine, University of Greifswald, Greifswald, Germany.

Publikováno v: Frontiers in immunology [Front Immunol] 2023 Oct 10; Vol. 14, pp. 1279539. Date of Electronic Publication: 2023 Oct 10 (Print Publication: 2023).

Activated regulatory T-cells promote duodenal bacterial translocation into necrotic areas in severe acute pancreatitis.

Autor: Glaubitz J; Department of Medicine A, university medicine Greifswald, Greifswald, Germany., Wilden A; Department of Medicine A, university medicine Greifswald, Greifswald, Germany., Frost F; Department of Medicine A, university medicine Greifswald, Greifswald, Germany., Ameling S; Interfaculty Institute for Genetics and Functional Genomics, Department of Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Homuth G; Interfaculty Institute for Genetics and Functional Genomics, Department of Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Mazloum H; Department of Medicine A, university medicine Greifswald, Greifswald, Germany., Rühlemann MC; Institute of Clinical Molecular Biology, Christian-Albrechts-Universität zu Kiel, Kiel, Germany.; Hannover Medical School, Institute for Medical Microbiology and Hospital Epidemiology, Hannover, Germany., Bang C; Institute of Clinical Molecular Biology, Christian-Albrechts-Universität zu Kiel, Kiel, Germany., Aghdassi AA; Department of Medicine A, university medicine Greifswald, Greifswald, Germany., Budde C; Department of Medicine A, university medicine Greifswald, Greifswald, Germany., Pickartz T; Department of Medicine A, university medicine Greifswald, Greifswald, Germany., Franke A; Institute of Clinical Molecular Biology, Christian-Albrechts-Universität zu Kiel, Kiel, Germany., Bröker BM; Department of Immunology, Universitätsmedizin Greifswald, Greifswald, Germany., Voelker U; Interfaculty Institute for Genetics and Functional Genomics, Department of Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Mayerle J; Medizinische Klinik und Poliklinik 2, Klinikum der Universitat Munchen, Munchen, Germany., Lerch MM; Department of Medicine A, university medicine Greifswald, Greifswald, Germany., Weiss FU; Department of Medicine A, university medicine Greifswald, Greifswald, Germany., Sendler M; Department of Medicine A, university medicine Greifswald, Greifswald, Germany matthias.sendler@uni-greifswald.de.

Publikováno v: Gut [Gut] 2023 Jul; Vol. 72 (7), pp. 1355-1369. Date of Electronic Publication: 2023 Jan 11.