Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Weishen He"'
Autor:
Shaohua Xu, Ruolan Fan, Lu Wang, Weishen He, Haixia Ge, Hailan Chen, Wen Xu, Jian Zhang, Wei Xu, Yaqian Feng, Zhimin Fan
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 236-251 (2022)
Using STAT3 inhibitors as a potential strategy in cancer therapy have attracted much attention. Recently, celastrol has been reported that it could directly bind to and suppress the activity of STAT3 in the cardiac dysfunction model. To explore more
Externí odkaz:
https://doaj.org/article/9f113a66351f404a93749d9c4821941f
Autor:
Xuan Mu, Weishen He, Victoria Abril Manjarrez Rivera, Raul Armando Duran De Alba, Dava J. Newman, Yu Shrike Zhang
Publikováno v:
Life Sciences in Space Research. 35:150-157
The spaceflight environment, including microgravity and radiation, may have considerable effects on the health and performance of astronauts, especially for long-duration and Martian missions. Conventional on-ground and in-space experimental approach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0c943ca530c04299f6b60c67113b986
https://doi.org/10.1016/j.lssr.2022.09.002
https://doi.org/10.1016/j.lssr.2022.09.002
Autor:
Shaohua Xu, Ruolan Fan, Lu Wang, Weishen He, Haixia Ge, Hailan Chen, Wen Xu, Jian Zhang, Wei Xu, Yaqian Feng, Zhimin Fan
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Record
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 236-251 (2022)
article-version (VoR) Version of Record
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 236-251 (2022)
Using STAT3 inhibitors as a potential strategy in cancer therapy have attracted much attention. Recently, celastrol has been reported that it could directly bind to and suppress the activity of STAT3 in the cardiac dysfunction model. To explore more
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8cb99d774a45c345b317497111894fd
https://doi.org/10.1080/14756366.2021.2001805
https://doi.org/10.1080/14756366.2021.2001805
Publikováno v:
Steroids. 180
Extracting organic compounds from plants and developing derivatives are essential methods for drug discovery. Diosgenin, extracted from Dioscoreaceae plants, is a type of spirostan steroid with various biological effects, including anti-inflammation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d24dbe854ff394d329a1783911781977
https://pubmed.ncbi.nlm.nih.gov/35217033
https://pubmed.ncbi.nlm.nih.gov/35217033
Publikováno v:
Pharmacological research. 167
Metabolic diseases are becoming increasingly common in modern society. Therefore, it is essential to develop effective drugs or new treatments for metabolic diseases. As an active ingredient derived from plants, celastrol has shown great potential in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c50c8f85aab8919e009051cde4c0dca
https://pubmed.ncbi.nlm.nih.gov/33753246
https://pubmed.ncbi.nlm.nih.gov/33753246
Aspirin inhibits prostaglandins to prevents colon tumor formation via down-regulating Wnt production
Autor:
Lei Tao, Shinghu Cheung, Zhen Li, Guoqiang Wang, Ligong Chen, Weishen He, Mingming Yang, Yong Zhang, Xincheng Zhong, Jinliang Yang, Mcdonald Fiona Mcdougall, Yaqian Feng
Publikováno v:
European journal of pharmacology. 906
According to numerous epidemiological studies, aspirin is a non-steroidal anti-inflammatory drug (NSAID) that reduces the occurrence and mortality of colorectal cancer (CRC). However, the underlying mechanisms are not well identified. In an effort to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c79439f798c035a27224406ea350e751
https://pubmed.ncbi.nlm.nih.gov/34033814
https://pubmed.ncbi.nlm.nih.gov/34033814