Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Weiran Feng"'
Autor:
Sherly I. Celada, Guoliang Li, Lindsay J. Celada, Wenfu Lu, Thanigaivelan Kanagasabai, Weiran Feng, Zhen Cao, Nazifa Salsabeel, Ninghui Mao, LaKendria K. Brown, Zaniya A. Mark, Michael G. Izban, Billy R. Ballard, Xinchun Zhou, Samuel E. Adunyah, Robert J. Matusik, Xiaofei Wang, Zhenbang Chen
Publikováno v:
Molecular Oncology, Vol 17, Iss 10, Pp 2126-2146 (2023)
Changes in FOXA1 (forkhead box protein A1) protein levels are well associated with prostate cancer (PCa) progression. Unfortunately, direct targeting of FOXA1 in progressive PCa remains challenging due to variations in FOXA1 protein levels, increased
Externí odkaz:
https://doaj.org/article/0cac8103e1024d5d960e34525c1fc17d
Autor:
Weiran Feng, Maria Jasin
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
BRCA2 mutations promote tumour formation while also paradoxically causing cell lethality. Here the authors generate conditional BRCA2 loss in a non-transformed human mammary cell line and see increased replication stress due to under-replication of D
Externí odkaz:
https://doaj.org/article/13ea0e66ca9041bb8737afe82abbcbd9
Autor:
Weiran Feng, Erik Ladewig, Nazifa Salsabeel, Huiyong Zhao, Young Sun Lee, Anuradha Gopalan, Hanzhi Luo, Wenfei Kang, Ning Fan, Eric Rosiek, Ignas Masilionis, Ronan Chaligné, Elisa de Stanchina, Yu Chen, Brett S. Carver, Christina S Leslie, Charles L. Sawyers
To gain insight into how ERG translocations cause prostate cancer, we performed single cell transcriptional profiling of an autochthonous mouse model at an early stage of disease initiation. Despite broad expression of ERG in prostate epithelial cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50983139181c40dc89c7a5a05a8530f9
https://doi.org/10.1101/2023.05.15.540839
https://doi.org/10.1101/2023.05.15.540839
Autor:
Qifeng Gao, Xiao Xiao, Ting Liu, Zhong Ren, Wei Ren, Yunya Zhan, Wenqian Wang, Weiran Feng, Li Ma, Le Qi, Zixian Zhang, Xubiao Luo, Shenglian Luo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abdf1cc448d7ed49036526f90c551919
https://doi.org/10.2139/ssrn.4427166
https://doi.org/10.2139/ssrn.4427166
Autor:
Weiran Feng, Xiao Xiao, Junjie Li, Qicheng Xiao, Li Ma, Qifeng Gao, Yuke Wan, Yutian Huang, Ting Liu, Xubiao Luo, Shenglian Luo, Guisheng Zeng, Kai Yu
Publikováno v:
Chemosphere. 315
Copper and zinc are toxic heavy metals in soils that require development of feasible strategies for remediation of contaminated soils around the mine areas. In this study, the processing conditions and mechanisms of immobilization and bioleaching for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71df982aea2f23c4b3014c8110c1db22
https://pubmed.ncbi.nlm.nih.gov/36603675
https://pubmed.ncbi.nlm.nih.gov/36603675
Autor:
Charles L. Sawyers, Teng Han, Danielle Choi, Brett S. Carver, Aura Agudelo Rivera, Rodrigo Romero, Huiyong Zhao, Qiao Wang, Maria Jasin, Elisa de Stanchina, Weiran Feng, Zhen Cao, Young Sun Lee, Pei Xin Lim, Hanzhi Luo, Chao Wu, Ninghui Mao
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Modeling cancer formation requires introduction of relevant oncogenic perturbations into normal cells in a tissue/cell-type–specific manner. Genetically engineered mouse models are powerful but require significant time and cost to gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c59513cefba23d84bf7329e482787e9
https://doi.org/10.1073/pnas.2110344118
https://doi.org/10.1073/pnas.2110344118
Autor:
Elizabeth V. Wasmuth, Arnaud Vanden Broeck, Justin R. LaClair, Elizabeth A. Hoover, Kayla E. Lawrence, Navid Paknejad, Kyrie Pappas, Doreen Matthies, Biran Wang, Weiran Feng, Philip A. Watson, John C. Zinder, Wouter R. Karthaus, M. Jason de la Cruz, Richard K. Hite, Katia Manova-Todorova, Zhiheng Yu, Susan T. Weintraub, Sebastian Klinge, Charles L. Sawyers
Publikováno v:
Molecular Cell. 82:2021-2031.e5
SummaryThe androgen receptor (AR) is a steroid receptor and master transcription factor that governs gene expression programs required for luminal development of prostate epithelium, formation of muscle tissue and maintenance of the male phenotype. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c6df221ecaedafa537ed3a95f5e24af
https://doi.org/10.1016/j.molcel.2022.03.035
https://doi.org/10.1016/j.molcel.2022.03.035
Autor:
Erika Brunet, Mark J. Tomishima, Fabio Vanoli, Khadija Lamribet, Loelia Babin, Weiran Feng, Maria Jasin
Publikováno v:
Proceedings of the National Academy of Sciences. 114:3696-3701
Significance Fusion genes resulting from recurrent chromosomal translocations are associated with several tumor types. Cell lines carrying translocations represent important models to study the oncogenic properties of fusion proteins and develop ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8a0a3824d23bbfae810f678acce41f8
https://doi.org/10.1073/pnas.1700622114
https://doi.org/10.1073/pnas.1700622114
Autor:
Weiran Feng, Zhen Cao, Pei Xin Lim, Huiyong Zhao, Hanzhi Luo, Ninghui Mao, Young Sun Lee, Rivera, Aura Agudelo, Choi, Danielle, Chao Wu, Teng Han, Romero, Rodrigo, de Stanchina, Elisa, Carver, Brett S., Qiao Wang, Jasin, Maria, Sawyers, Charles L.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 8/10/2021, Vol. 118 Issue 32, p1-7, 7p
Autor:
Weiran Feng, Maria Jasin
BRCA2 deficiency causes genome instability and breast and ovarian cancer predisposition, but also paradoxically promotes cell lethality. The nature of the acute, detrimental consequences of BRCA2 loss is not fully understood. We recently generated BR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45d2995c4361a1b2e57572d4f9123743