Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Weiqun Fang"'
Autor:
Yu Chen, Zhuoyi Liang, Erkang Fei, Yuewen Chen, Xiaopu Zhou, Weiqun Fang, Wing-Yu Fu, Amy K Y Fu, Nancy Y Ip
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133115 (2015)
During development, scaffold proteins serve as important platforms for orchestrating signaling complexes to transduce extracellular stimuli into intracellular responses that regulate dendritic spine morphology and function. Axin ("axis inhibitor") is
Externí odkaz:
https://doaj.org/article/76c38a9d723e492c8a32fa9952119e37
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Scientific Reports
Major depressive disorders are emerging health problems that affect millions of people worldwide. However, treatment options and targets for drug development are limited. Impaired adult hippocampal neurogenesis is emerging as a key contributor to the
Publikováno v:
Cell Reports, Vol 9, Iss 5, Pp 1635-1643 (2014)
Summary: The functional integrity of the neocortex depends upon proper numbers of excitatory and inhibitory neurons; however, the consequences of dysregulated neuronal production during the development of the neocortex are unclear. As excess cortical
Publikováno v:
Neuron. 79:665-679
Summary The expansion of the mammalian cerebral cortex is safeguarded by a concerted balance between amplification and neuronal differentiation of intermediate progenitors (IPs). Nonetheless, the molecular controls governing these processes remain un
Autor:
Sheng-Cai Lin, Rui Li, Nancy Y. Ip, Yu Pong Ng, Weiqun Fang, Yu Chen, Amy K.Y. Fu, Jacque P.K. Ip
Publikováno v:
The Journal of Neuroscience. 31:13613-13624
Axon formation is critical for the establishment of connections between neurons, which is a prerequisite for the development of neural circuitry. Kinases such as cyclin-dependent kinase 5 (Cdk5) and glycogen synthase kinase-3β (GSK-3β), have been i
Autor:
Chaoneng Ji, Jing Peng, Tonghai Dou, Yumin Mao, Rui Qiu, Weiqun Fang, Fei Chen, Congjing Feng, Xie Yi, Nan Zheng
Publikováno v:
DNA Sequence. 17:282-286
Pre-mRNA splicing allows individual genes to produce multiple protein isoforms with diverse functions. Recognition of functional splice sites in pre-mRNAs is very important in this splicing process and requires some protein auxiliary factors such as
Cdk5-dependent Mst3 phosphorylation and activity regulate neuronal migration through RhoA inhibition
Autor:
Weiqun Fang, Zhenguo Wu, Yu Pong Ng, Jing Tang, Amy K.Y. Fu, Nancy Y. Ip, Tao Ye, Wing-Ho Yung, Jacque P.K. Ip
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 34(22)
The radial migration of newborn neurons is critical for the lamination of the cerebral cortex. Proper neuronal migration requires precise and rapid reorganization of the actin and microtubule cytoskeleton. However, the underlying signaling mechanisms
Autor:
Yuewen Chen, Amy K.Y. Fu, Zhuoyi Liang, Nancy Y. Ip, Xiaopu Zhou, Weiqun Fang, Wing Yu Fu, Erkang Fei, Yu Chen
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133115 (2015)
PLoS ONE
PLoS ONE
During development, scaffold proteins serve as important platforms for orchestrating signaling complexes to transduce extracellular stimuli into intracellular responses that regulate dendritic spine morphology and function. Axin ("axis inhibitor") is
Autor:
Yi Guo, Xin Ye, Weiqun Fang, Xie Yi, Wei Jin, Shaohua Gu, Yumin Mao, Jianliang Dai, Jiaping Song, Chaoneng Ji
Publikováno v:
DNA sequence : the journal of DNA sequencing and mapping. 15(3)
Bardet-Biedl syndrome (BBS) is a heterogeneous multisystemic disorder characterized primarily by five cardinal features of retinal degeneration, obesity, polydactyly, hypogenitalism and mental retardation. To date, six distinct BBS loci that have bee